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The map label for this gene is yngJ [H]

Identifier: 197105960

GI number: 197105960

Start: 2864219

End: 2865385

Strand: Reverse

Name: yngJ [H]

Synonym: PHZ_c2499

Alternate gene names: 197105960

Gene position: 2865385-2864219 (Counterclockwise)

Preceding gene: 197105962

Following gene: 197105959

Centisome position: 71.7

GC content: 68.29

Gene sequence:

>1167_bases
ATGGATTTGACCCTGACGCCCGAACTGTCGGCCTTCCGCGAGGAGGTGCGGGCGTTCCTGGCGGCCCATCGCGGCGAGTA
CGAAGCGGGCCAGCCGAAGGATCCCCTGGCCTGGCAGCGCCTCCTGATCGAGCACGGCTATGCGGCCCGGACGATCCCGA
AGGCGTACGGCGGCTTCGGCGCTCAGCCCGACATACTGAAGGCGCGGATCATCGCCGAGGCCTTCATCGCCGCCGGCGCG
CCGCGCGGCCTCGCCAACCAGGGGATCTCGATGCTGGTCCCGACCCTGCTGGAGGTGGGCTCGGAAGATCAGAAGACGCG
CTGGATCGGGCCCACCCTGCGCGGCGAGGTGGTCTGGTGCCAGGGCTACTCCGAGCCGGGCGCGGGCTCGGACCTCGCCT
CCCTGCAGACCCGGGCGGTGGAGGACGGCGAGGACTTCGTCATCTCGGGTTCGAAGATCTGGACCAGCACCGCCCACCTC
GCGGACATGATGTTCTGCCTGGTGCGGACCGAGCCCGACAAGCCGAAGCACGAGGGCATCAGCTACGTCCTGATCCCGAT
GGACACGCCCGGGATCGAGGTGCGGCCGCTGAAGACCATGACGGGCTACGCCGAATTCAACGAGGTGTTCTTCACGGATG
TGCGTGTTCCCCAGGCCAACGTCGTGGGCGGGCGCGGGCGCGGCTGGCAGGTGGCCAACACCACGCTCAAGCACGAGCGC
GGAATGCTGGGCGATCCCAATGCGACCGAAGCCCGTCTGGCGGCCCTCATCGAGCTGATGAAGACCGAGACGGTCGATGG
CGAGCGGATCATCGACAACCCGGTCTTCCGCGACCGGCTGATGCAGCTGCAGGCGCGGGTCTTCGCCATGAAGTTCAACG
GCCTCCGTGTCCTGACCGACGAGACCGCGGGTCTCGCACGCCTGATCGTCAAGCTGCAGGGCTGCGAGCTGAACCATCAG
GTGGCGGCTCTGGCCATCGACGCCCTGGGCGAGCTCGGCGTGCTGTACCACGAGGGGCCGCACCTGCGGGCCAAGGGCTC
GTGGCAGCGCAACTACATGTTCGACCTCGGCCTCATCATCGGCGGCGGCACGGCGCAGATCCAGAAGAACATCATCGCCG
AGCGGGGCCTTGGCCTGCCGCGCGAACCCAAGACGGTGGGGGCCTGA

Upstream 100 bases:

>100_bases
GGCGGTCTCCGTTCTCTTGCATCCGGGCTGACGCCAGGGCGCCGTTGCCTAGATGCGCAAACGCGGTTGCAGTGACAGAG
GCACAGGAGCGCGAGGATAC

Downstream 100 bases:

>100_bases
CATGAGGTTCGCGCTCTCCGAGGACCAGGTCCTGCTGCAGGACAGCCTGGCGAAGGCCCTGGCCGAGCTCGCGCCCCTGG
AGCGGGTGCGGCGCTTCGCC

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFGAQPDILKARIIAEAFIAAGA
PRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWCQGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHL
ADMMFCLVRTEPDKPKHEGISYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHER
GMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTDETAGLARLIVKLQGCELNHQ
VAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLIIGGGTAQIQKNIIAERGLGLPREPKTVGA

Sequences:

>Translated_388_residues
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFGAQPDILKARIIAEAFIAAGA
PRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWCQGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHL
ADMMFCLVRTEPDKPKHEGISYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHER
GMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTDETAGLARLIVKLQGCELNHQ
VAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLIIGGGTAQIQKNIIAERGLGLPREPKTVGA
>Mature_388_residues
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFGAQPDILKARIIAEAFIAAGA
PRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWCQGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHL
ADMMFCLVRTEPDKPKHEGISYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHER
GMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTDETAGLARLIVKLQGCELNHQ
VAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLIIGGGTAQIQKNIIAERGLGLPREPKTVGA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=26.8041237113402, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI211971008, Length=258, Percent_Identity=30.2325581395349, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI48976061, Length=258, Percent_Identity=30.2325581395349, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4557233, Length=350, Percent_Identity=27.1428571428571, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557231, Length=226, Percent_Identity=29.2035398230088, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI187960098, Length=234, Percent_Identity=28.6324786324786, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501859, Length=309, Percent_Identity=27.5080906148867, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38505218, Length=146, Percent_Identity=34.2465753424658, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=24.3523316062176, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=25, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI76496475, Length=279, Percent_Identity=27.2401433691756, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557235, Length=279, Percent_Identity=27.2401433691756, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7656849, Length=249, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI21361497, Length=355, Percent_Identity=25.0704225352113, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786223, Length=317, Percent_Identity=24.2902208201893, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=312, Percent_Identity=23.3974358974359, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=252, Percent_Identity=32.1428571428571, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=206, Percent_Identity=33.0097087378641, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=206, Percent_Identity=33.0097087378641, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=249, Percent_Identity=28.9156626506024, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=201, Percent_Identity=30.8457711442786, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=185, Percent_Identity=30.8108108108108, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=25.8426966292135, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=286, Percent_Identity=27.6223776223776, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=25.7225433526012, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=27.8260869565217, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=244, Percent_Identity=28.6885245901639, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=229, Percent_Identity=25.764192139738, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=229, Percent_Identity=25.764192139738, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=157, Percent_Identity=28.6624203821656, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24660351, Length=234, Percent_Identity=30.3418803418803, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356377, Length=209, Percent_Identity=32.0574162679426, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281363737, Length=280, Percent_Identity=27.1428571428571, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666513, Length=255, Percent_Identity=26.2745098039216, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24646207, Length=321, Percent_Identity=28.0373831775701, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=215, Percent_Identity=29.7674418604651, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42451; Mature: 42451

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFG
CCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHCCCC
AQPDILKARIIAEAFIAAGAPRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWC
CCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCCCEEEE
QGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHLADMMFCLVRTEPDKPKHEGI
ECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCC
SYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHER
EEEEEECCCCCCEEEECHHHHCHHHHHHEEEEEECCCCCCEECCCCCCEEECCCHHHHCC
GMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTD
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEC
ETAGLARLIVKLQGCELNHQVAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLII
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCEEEEEEEEE
GGGTAQIQKNIIAERGLGLPREPKTVGA
CCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFG
CCCEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHCCCC
AQPDILKARIIAEAFIAAGAPRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWC
CCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCCEECCCCCCCCEEEE
QGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHLADMMFCLVRTEPDKPKHEGI
ECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHCCC
SYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHER
EEEEEECCCCCCEEEECHHHHCHHHHHHEEEEEECCCCCCEECCCCCCEEECCCHHHHCC
GMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTD
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEC
ETAGLARLIVKLQGCELNHQVAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLII
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCCEEECCCCCCCEEEEEEEEE
GGGTAQIQKNIIAERGLGLPREPKTVGA
CCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]