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The map label for this gene is exuR [H]

Identifier: 197105938

GI number: 197105938

Start: 2838417

End: 2839160

Strand: Direct

Name: exuR [H]

Synonym: PHZ_c2477

Alternate gene names: 197105938

Gene position: 2838417-2839160 (Clockwise)

Preceding gene: 197105937

Following gene: 197105944

Centisome position: 71.03

GC content: 72.04

Gene sequence:

>744_bases
ATGGCCAGCGGCAAACTCTACCGGCGCCTCGCGGACTCGATCGCCGCGGAGATCGAGAGCGGCAAGTACGCCGTGGGCGA
GCGCCTGCCCACCGAGCGCGAGCTGGCCGAGCAGTACGGCGTCAGCCGGCCCACCCTGCGCGAGGCGCTGATCGCCCTGG
AGATGCTGGGGATGATCGAGGCCCGCCACGGCCTCGGAATCTACGTCACCCGCGCCCAGGTCCCGCTGACGGCCTCGGCC
TACGACTTCGAGATCGGCGCGTTCGAGCTGATCGAGGCCCGGCGTCTGTTCGAGGGCGAAGCCGCGGCCCTGGCCGCCGC
CACCATCGACGACGAGCAACTCGCCGAGCTGGACCGCCTGCTCGCCCTGATGGCCGACGAGGACGAGCTGAAGGGCGAGG
ACGCTGACAAGGAGTTCCACATGGTGATCGCCCGGGCGACCGGGAACGGCGCGATCATCGCGACCATCGAGAACCTGTGG
GAGCTGCGCAACCGCTCGCCGCTCGCGCGCAACATCCTCACCCGCGCCCGCGGCCTGGGCCTGGAGCCGCGCATCGCCGA
GCACCGCCGCGTGCTGGACGCCCTGCGCGCCCATGACCCCGCCGCCGCGCGCCAGGCGATGCGCGACCACCTGGAGCGGG
TGATCGAACACCTGCTGCGCGCCACCGAGACCGAGGCGCTGGAACGGGCCCAGCAGGAGAGCAAGGCCCGCCGCAGCCAG
ATCGCCAAGCGCGTGGCGATCTAG

Upstream 100 bases:

>100_bases
CGACTGGTGAGGGCGCGCCCCTTCTGTCCCGCGGGAATGGTGGAGTATGGTTGCGCGTAGAATCCCCCCGTCGGGCGGCA
AGGCGAAAAGCCAGGAGACG

Downstream 100 bases:

>100_bases
GAGCCGCTAGCGCGCTTCGGCCGCGCCCTGGCTCAACCAGTGCATGACGTTCAGGAGGAACTGCTTGTTCTGGCCGGCGC
CGTCGGCCCGGAAGCCCATC

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MASGKLYRRLADSIAAEIESGKYAVGERLPTERELAEQYGVSRPTLREALIALEMLGMIEARHGLGIYVTRAQVPLTASA
YDFEIGAFELIEARRLFEGEAAALAAATIDDEQLAELDRLLALMADEDELKGEDADKEFHMVIARATGNGAIIATIENLW
ELRNRSPLARNILTRARGLGLEPRIAEHRRVLDALRAHDPAAARQAMRDHLERVIEHLLRATETEALERAQQESKARRSQ
IAKRVAI

Sequences:

>Translated_247_residues
MASGKLYRRLADSIAAEIESGKYAVGERLPTERELAEQYGVSRPTLREALIALEMLGMIEARHGLGIYVTRAQVPLTASA
YDFEIGAFELIEARRLFEGEAAALAAATIDDEQLAELDRLLALMADEDELKGEDADKEFHMVIARATGNGAIIATIENLW
ELRNRSPLARNILTRARGLGLEPRIAEHRRVLDALRAHDPAAARQAMRDHLERVIEHLLRATETEALERAQQESKARRSQ
IAKRVAI
>Mature_246_residues
ASGKLYRRLADSIAAEIESGKYAVGERLPTERELAEQYGVSRPTLREALIALEMLGMIEARHGLGIYVTRAQVPLTASAY
DFEIGAFELIEARRLFEGEAAALAAATIDDEQLAELDRLLALMADEDELKGEDADKEFHMVIARATGNGAIIATIENLWE
LRNRSPLARNILTRARGLGLEPRIAEHRRVLDALRAHDPAAARQAMRDHLERVIEHLLRATETEALERAQQESKARRSQI
AKRVAI

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=229, Percent_Identity=34.4978165938865, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790780, Length=234, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790032, Length=240, Percent_Identity=32.0833333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786303, Length=239, Percent_Identity=32.2175732217573, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789353, Length=223, Percent_Identity=30.4932735426009, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789621, Length=230, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27496; Mature: 27365

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGKLYRRLADSIAAEIESGKYAVGERLPTERELAEQYGVSRPTLREALIALEMLGMIE
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARHGLGIYVTRAQVPLTASAYDFEIGAFELIEARRLFEGEAAALAAATIDDEQLAELDRL
HCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
LALMADEDELKGEDADKEFHMVIARATGNGAIIATIENLWELRNRSPLARNILTRARGLG
HHHHCCCHHHCCCCCCCCEEEEEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCC
LEPRIAEHRRVLDALRAHDPAAARQAMRDHLERVIEHLLRATETEALERAQQESKARRSQ
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKRVAI
HHHHHCC
>Mature Secondary Structure 
ASGKLYRRLADSIAAEIESGKYAVGERLPTERELAEQYGVSRPTLREALIALEMLGMIE
CCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARHGLGIYVTRAQVPLTASAYDFEIGAFELIEARRLFEGEAAALAAATIDDEQLAELDRL
HCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
LALMADEDELKGEDADKEFHMVIARATGNGAIIATIENLWELRNRSPLARNILTRARGLG
HHHHCCCHHHCCCCCCCCEEEEEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHCCC
LEPRIAEHRRVLDALRAHDPAAARQAMRDHLERVIEHLLRATETEALERAQQESKARRSQ
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKRVAI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA