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The map label for this gene is gnl [H]

Identifier: 197105928

GI number: 197105928

Start: 2824485

End: 2825363

Strand: Reverse

Name: gnl [H]

Synonym: PHZ_c2467

Alternate gene names: 197105928

Gene position: 2825363-2824485 (Counterclockwise)

Preceding gene: 197105929

Following gene: 197105927

Centisome position: 70.7

GC content: 71.9

Gene sequence:

>879_bases
ATGAAGGTCCTCTCCGAACCCGACTGCGTGCTGCGCGCCGACGCCGAGCTGGGCGAGGGGCCCGTCTGGCGGGCCGACGA
CGACGCGGTCTGGTTCGTGGACATCAAGGGCCGCCGCATCCACCGCTACGAGCCGGTCACCGGCGCGGCCTGGAGCTGGG
CGGCGCCCGCCCAGCCGGGGTTCATCGCCCCGGTCGCCGGCGGGGGCTGGGTCGCAGGCCTGAAGACCGGCCTGCACCGG
TTCGAGCCGCGCGGCGGCCGTTTCGAGCTGATCACGGCCGTCGAGGACCCGTCCCTGGACAACCGCCTGAACGACGGCTT
CGTGGATGCGAAGGGCCGGCTCTGGTTCGGTTCGATGCACGACGGCGAGACGGCGCTGACCGGGGCGCTCTATCGGCTGG
ACGAGCGCGGCCTGCAGCGCTGCGACACCGGCTACTGCATCACCAACGGCCCGGCGGCGAGCCCCGACGGGCGGACGCTC
TATCACACCGACACCCTGCAGAAGACGATCTACGCCTTCGACCTCTCGCCGGCCGGCGAGCTGTCGAACAAGCGGGTGTT
CGCGCGCATCGAGGAAGGCGGCGGCTATCCCGACGGGCCCGCGGTGGACGCCGAGGGCTGCGTCTGGACGGGCCTCTTCG
CCGGCTGGCACGTACGGCGCTATTCGCCCAAGGGCGAGCTCCTCGCCAAGGTCGGGTTCCCCGTCGCCAACATCACCAAG
CTGGCCTTCGGCGGCGACGACCTGACGAGCGTCTACGCCACCACCGCCTGGAAGGGCCTCTCGGCCGACGAGCGCGAGAA
GCAGCCGCTCGCCGGCGGCCTCTTCCGGTTCGAGGTCGACGTCCCCGGCCTGCCGCAGAACCAGATGGCCCATGCCTGA

Upstream 100 bases:

>100_bases
GGATCGAGCCCGCGGACGTGGCGGCGCTGGTGCTCTTCCTGGCTTCGGACGACGCGCGCATGTGCACCGGCCACGAATAC
TGGATCGACGCAGGCTGGCG

Downstream 100 bases:

>100_bases
CCGCAAGCCCGCGCGCCCCTTCCGGTCCCGGGAGTGGTTCGCCGCCCCCGAACGCTCGGACATGACCGCCCTCTACCTCG
AGCGGTTCATGAACTACGGC

Product: gluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKVLSEPDCVLRADAELGEGPVWRADDDAVWFVDIKGRRIHRYEPVTGAAWSWAAPAQPGFIAPVAGGGWVAGLKTGLHR
FEPRGGRFELITAVEDPSLDNRLNDGFVDAKGRLWFGSMHDGETALTGALYRLDERGLQRCDTGYCITNGPAASPDGRTL
YHTDTLQKTIYAFDLSPAGELSNKRVFARIEEGGGYPDGPAVDAEGCVWTGLFAGWHVRRYSPKGELLAKVGFPVANITK
LAFGGDDLTSVYATTAWKGLSADEREKQPLAGGLFRFEVDVPGLPQNQMAHA

Sequences:

>Translated_292_residues
MKVLSEPDCVLRADAELGEGPVWRADDDAVWFVDIKGRRIHRYEPVTGAAWSWAAPAQPGFIAPVAGGGWVAGLKTGLHR
FEPRGGRFELITAVEDPSLDNRLNDGFVDAKGRLWFGSMHDGETALTGALYRLDERGLQRCDTGYCITNGPAASPDGRTL
YHTDTLQKTIYAFDLSPAGELSNKRVFARIEEGGGYPDGPAVDAEGCVWTGLFAGWHVRRYSPKGELLAKVGFPVANITK
LAFGGDDLTSVYATTAWKGLSADEREKQPLAGGLFRFEVDVPGLPQNQMAHA
>Mature_292_residues
MKVLSEPDCVLRADAELGEGPVWRADDDAVWFVDIKGRRIHRYEPVTGAAWSWAAPAQPGFIAPVAGGGWVAGLKTGLHR
FEPRGGRFELITAVEDPSLDNRLNDGFVDAKGRLWFGSMHDGETALTGALYRLDERGLQRCDTGYCITNGPAASPDGRTL
YHTDTLQKTIYAFDLSPAGELSNKRVFARIEEGGGYPDGPAVDAEGCVWTGLFAGWHVRRYSPKGELLAKVGFPVANITK
LAFGGDDLTSVYATTAWKGLSADEREKQPLAGGLFRFEVDVPGLPQNQMAHA

Specific function: Unknown

COG id: COG3386

COG function: function code G; Gluconolactonase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMP-30/CGR1 family [H]

Homologues:

Organism=Homo sapiens, GI23111021, Length=279, Percent_Identity=31.5412186379928, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4759036, Length=279, Percent_Identity=31.5412186379928, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24646912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646910, Length=276, Percent_Identity=29.7101449275362, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45551448, Length=265, Percent_Identity=28.3018867924528, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24641471, Length=265, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI18860103, Length=265, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24641469, Length=265, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR013658
- InterPro:   IPR005511 [H]

Pfam domain/function: PF08450 SGL [H]

EC number: NA

Molecular weight: Translated: 31680; Mature: 31680

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLSEPDCVLRADAELGEGPVWRADDDAVWFVDIKGRRIHRYEPVTGAAWSWAAPAQPG
CCCCCCCCEEEEECCCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCC
FIAPVAGGGWVAGLKTGLHRFEPRGGRFELITAVEDPSLDNRLNDGFVDAKGRLWFGSMH
EEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCEEEEECCC
DGETALTGALYRLDERGLQRCDTGYCITNGPAASPDGRTLYHTDTLQKTIYAFDLSPAGE
CCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECHHHCEEEEEEECCCCCC
LSNKRVFARIEEGGGYPDGPAVDAEGCVWTGLFAGWHVRRYSPKGELLAKVGFPVANITK
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHCCEEEEEECCCCCEEEECCCCHHHEEE
LAFGGDDLTSVYATTAWKGLSADEREKQPLAGGLFRFEVDVPGLPQNQMAHA
EEECCCCHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHCCCC
>Mature Secondary Structure
MKVLSEPDCVLRADAELGEGPVWRADDDAVWFVDIKGRRIHRYEPVTGAAWSWAAPAQPG
CCCCCCCCEEEEECCCCCCCCCEECCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCC
FIAPVAGGGWVAGLKTGLHRFEPRGGRFELITAVEDPSLDNRLNDGFVDAKGRLWFGSMH
EEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCEEEEECCC
DGETALTGALYRLDERGLQRCDTGYCITNGPAASPDGRTLYHTDTLQKTIYAFDLSPAGE
CCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECHHHCEEEEEEECCCCCC
LSNKRVFARIEEGGGYPDGPAVDAEGCVWTGLFAGWHVRRYSPKGELLAKVGFPVANITK
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHCCEEEEEECCCCCEEEECCCCHHHEEE
LAFGGDDLTSVYATTAWKGLSADEREKQPLAGGLFRFEVDVPGLPQNQMAHA
EEECCCCHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]