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The map label for this gene is yybO [H]

Identifier: 197105902

GI number: 197105902

Start: 2789659

End: 2791029

Strand: Direct

Name: yybO [H]

Synonym: PHZ_c2441

Alternate gene names: 197105902

Gene position: 2789659-2791029 (Clockwise)

Preceding gene: 197105901

Following gene: 197105903

Centisome position: 69.81

GC content: 63.46

Gene sequence:

>1371_bases
ATGGCTGAGCTGGCGCGCCTTTCAGGTCTGACGCCTGACGCCGGGTACCCCACCGCTCTGCGCGGATGGTTCGCGGTCGC
GATGCTCACGGTCGTCTACGTCTTTTCGTATGTGGACCGGACAATCCTGACGCTTCTCGTTGGTCCTATCCGGGCGGACC
TGCAGATCAGTGACACGCAGGTCAGCCTGCTGCACGGCTTCGCCTTTGCGATCTTCTACACTCTGCTCGGACTGCCTTTT
GGTCGGCTTGTCGACCGGCGGCACCGGATCGGGATTATCTCCATCGCCATCGCGGTCTGGAGCGTGATGACGGCCCTGTG
CGGGTTCGCGAAGTCCTTCTTCCAGCTTTTCATGGCTCGGATTGGGGTTGGAGTTGGCGAGGCGGCGCTTTCACCGGCGG
CCTACTCGATCATTACTGACTACTTCCCGCCCGAAAAGCGCTCCCGCGCGCTGAGCACCTATGTGCTCGGAAGCTACCTC
GGGATGGCGATGGCCTACATCATCGGTGGCGGCCTGGTGGCTATGCTCGCAGCGGCGCCGCTGTGGGACGTTCCTGTGGT
CGGCCCCATGGAAGGGTGGCGCATCGCCTTCATGGTGGTCGGTCTTCCCGGATTGCTGCTCGCGCCTTTGATCTGGGCGG
TGCGGGAGCCGAAGCGGAGGGGGACCCTCCGCAAAGGGGACGAGACGGTCAGATCGGTGCCGCTGCGCGAACTTGGCGCC
TACCTGGTGTCGCATTGGAAGACCTACAGCGCACACTTCCTTGGCTTTGGCCTTCTGTGCCTCCTGATCAATGGCATGGC
CCTGTGGACGCCGACGTTTCTGATCCGAATCCACGGCTGGAGCGTCGGCGAGGCGGGCGCTGTCTACGGCCTCATGATCG
GCGTCTTTGGCGGATCTGGGGTGGTCGCTGGCGGCTGGCTTTCCGATTACCTCCAGAAGCGCGGCCAGCGTAGCGCCTGC
TTCATTACTGCGGCGATGGGCTCAGGCCTGGCGATCATCCCGACCGTCCTCATGCCGATCGTGCCAGACATCAGGGCCGT
GCTCTTCCTGATGGCCCCGGCGCTGTTTTTCGGCGCCGTCCCGTTCGGCCTCGCCGTCTCAGCGCTTCAGCAGATCACGC
CCAATCAGATGCGCGGGCAGGTTTCGGCCATGTACCAGTTCTTCAACAACATGCTCGGGATCGGCTGCGGACCGCTGATG
GTCGCTCTGCTCACCGACTATGCCTTCAGAGACGAACTCGCTCTCGGCTATTCGATGTCGATCGTGGGCGGTGTGTCGGC
CCTGGTGGCGACGCTGATCCTGGTGATCGGGATCAGGCCTTACCTGTCCAGCCTGGAGCGTGCCGACGCCTGGAAACAGG
CGGGAGACTAG

Upstream 100 bases:

>100_bases
AGCATGCACTATCAGCTCACCAGCTCGCTCGCGCTGAGCAATCCTGGCAAGCGCGAGGCGAAGCTGCTCTGGGTCGGCTC
TGTCGTGCTGTTCTCCTCCA

Downstream 100 bases:

>100_bases
AATGAAAATTTCATCTGATCAGCAGCACGTCGAGTTCACGACGGCGCTGGGCGGGATTGTCATATCTGTCGACCGCGCCG
CCGCCCCCCTCACCGCCTCC

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAELARLSGLTPDAGYPTALRGWFAVAMLTVVYVFSYVDRTILTLLVGPIRADLQISDTQVSLLHGFAFAIFYTLLGLPF
GRLVDRRHRIGIISIAIAVWSVMTALCGFAKSFFQLFMARIGVGVGEAALSPAAYSIITDYFPPEKRSRALSTYVLGSYL
GMAMAYIIGGGLVAMLAAAPLWDVPVVGPMEGWRIAFMVVGLPGLLLAPLIWAVREPKRRGTLRKGDETVRSVPLRELGA
YLVSHWKTYSAHFLGFGLLCLLINGMALWTPTFLIRIHGWSVGEAGAVYGLMIGVFGGSGVVAGGWLSDYLQKRGQRSAC
FITAAMGSGLAIIPTVLMPIVPDIRAVLFLMAPALFFGAVPFGLAVSALQQITPNQMRGQVSAMYQFFNNMLGIGCGPLM
VALLTDYAFRDELALGYSMSIVGGVSALVATLILVIGIRPYLSSLERADAWKQAGD

Sequences:

>Translated_456_residues
MAELARLSGLTPDAGYPTALRGWFAVAMLTVVYVFSYVDRTILTLLVGPIRADLQISDTQVSLLHGFAFAIFYTLLGLPF
GRLVDRRHRIGIISIAIAVWSVMTALCGFAKSFFQLFMARIGVGVGEAALSPAAYSIITDYFPPEKRSRALSTYVLGSYL
GMAMAYIIGGGLVAMLAAAPLWDVPVVGPMEGWRIAFMVVGLPGLLLAPLIWAVREPKRRGTLRKGDETVRSVPLRELGA
YLVSHWKTYSAHFLGFGLLCLLINGMALWTPTFLIRIHGWSVGEAGAVYGLMIGVFGGSGVVAGGWLSDYLQKRGQRSAC
FITAAMGSGLAIIPTVLMPIVPDIRAVLFLMAPALFFGAVPFGLAVSALQQITPNQMRGQVSAMYQFFNNMLGIGCGPLM
VALLTDYAFRDELALGYSMSIVGGVSALVATLILVIGIRPYLSSLERADAWKQAGD
>Mature_455_residues
AELARLSGLTPDAGYPTALRGWFAVAMLTVVYVFSYVDRTILTLLVGPIRADLQISDTQVSLLHGFAFAIFYTLLGLPFG
RLVDRRHRIGIISIAIAVWSVMTALCGFAKSFFQLFMARIGVGVGEAALSPAAYSIITDYFPPEKRSRALSTYVLGSYLG
MAMAYIIGGGLVAMLAAAPLWDVPVVGPMEGWRIAFMVVGLPGLLLAPLIWAVREPKRRGTLRKGDETVRSVPLRELGAY
LVSHWKTYSAHFLGFGLLCLLINGMALWTPTFLIRIHGWSVGEAGAVYGLMIGVFGGSGVVAGGWLSDYLQKRGQRSACF
ITAAMGSGLAIIPTVLMPIVPDIRAVLFLMAPALFFGAVPFGLAVSALQQITPNQMRGQVSAMYQFFNNMLGIGCGPLMV
ALLTDYAFRDELALGYSMSIVGGVSALVATLILVIGIRPYLSSLERADAWKQAGD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=341, Percent_Identity=27.5659824046921, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI14042968, Length=341, Percent_Identity=27.5659824046921, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI185136021, Length=421, Percent_Identity=24.2280285035629, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI215490102, Length=174, Percent_Identity=31.6091954022989, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI215490100, Length=307, Percent_Identity=27.3615635179153, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI194239645, Length=297, Percent_Identity=25.2525252525253, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI2367379, Length=408, Percent_Identity=25, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=25.9345794392523, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=23.8532110091743, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=460, Percent_Identity=24.3478260869565, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367193, Length=303, Percent_Identity=25.7425742574257, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=443, Percent_Identity=25.0564334085779, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539092, Length=421, Percent_Identity=23.0403800475059, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209775, Length=425, Percent_Identity=21.4117647058824, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992409, Length=472, Percent_Identity=21.1864406779661, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654039, Length=318, Percent_Identity=27.6729559748428, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17864456, Length=318, Percent_Identity=27.6729559748428, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654037, Length=328, Percent_Identity=26.8292682926829, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24654041, Length=328, Percent_Identity=26.8292682926829, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24654044, Length=273, Percent_Identity=27.4725274725275, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640209, Length=172, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49065; Mature: 48934

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AELARLSGLTPDAGYPTALRGWFAVAMLTVVYVFSYVDRTILTLLVGPIRADLQISDTQ
CCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]