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The map label for this gene is gno [H]

Identifier: 197105679

GI number: 197105679

Start: 2505155

End: 2505892

Strand: Direct

Name: gno [H]

Synonym: PHZ_c2216

Alternate gene names: 197105679

Gene position: 2505155-2505892 (Clockwise)

Preceding gene: 197105672

Following gene: 197105680

Centisome position: 62.69

GC content: 73.98

Gene sequence:

>738_bases
ATGTCCGCCCCCACGGGAGCCTGCCTCGTCGTCGGCGTCGGCGACGGCCTCGGCTCGGCCATCGCCCGCGCCTTCGCCGC
CGAGGGTCTCGCCGTCTGCATGACGCGCCGCCCGCGTCACCTCGAGGCGCTGGAGGCCCTGGCCCAGGATATCCGCGACG
CCGGCGGCCGGGCCCATGCCTATGGTGTCGACGCCCGCTCCGAGGACGAGATGGCCGCCCTCTTCGCCGCGATCGAGCGC
GACGTCGGCCCGCTCGAGGTCGTGGTCTTCAACATCGGCGCGAACGTCCGCTTTCCCATCCGCGAGACCACCGCCCGGGT
GTTCCACAAGGTCTGGGAGATGGCCTGCTTCGCCGGCTTCCTCGCCGGCCGCGAGGCCGCCAGGGTCATGGTCCCGCGCG
GCCGAGGCACGATCCTCTTCACCGGCGCCACCGCCAGCGTGCGCGGGCGCGACGGCTTCGCCGCCTTCGCCGCCGCCAAG
CACGGCCTGCGCGCCGTGGCCCAGAGCATGGCCCGCGAGCTCGGCCCGGAAGGGATCCACGTCGCCCACGTGGTCATCGA
CGGCGGGATCGACGGGACCTTCATCCGCGAGAACCGGCCCGACGCCGAGGCCGCCCTGGCCCGCGACGAGATCCTCCGTC
CCGAGGACGTCGCGCTCAACTACGTGGCCCTGCACCGCCAGCCGCGCTCGGCCTGGACCCACGAACTCGACCTGCGCCCC
TGGCGCGAAGCCTTCTGA

Upstream 100 bases:

>100_bases
CCACTTCATCCGACGCGCTCCTGCGGTTCGCGCCATGGTCCCATTGACTCCGTTCGGATTCAATACGAACGTCCGTCCAG
ATTCCGAACGGAGCCGCGCC

Downstream 100 bases:

>100_bases
AGGGAGCCCCCAGTGGCCCAACCCGCGCCCCGCCCCGCGATCGACTTCGTCTTCGACTTCGGCAGCCCCAACGGCTACCT
GGCCTGGAAGGTGCTCCCTG

Product: oxidoreductase, short-chain dehydrogenase/reductase family

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSAPTGACLVVGVGDGLGSAIARAFAAEGLAVCMTRRPRHLEALEALAQDIRDAGGRAHAYGVDARSEDEMAALFAAIER
DVGPLEVVVFNIGANVRFPIRETTARVFHKVWEMACFAGFLAGREAARVMVPRGRGTILFTGATASVRGRDGFAAFAAAK
HGLRAVAQSMARELGPEGIHVAHVVIDGGIDGTFIRENRPDAEAALARDEILRPEDVALNYVALHRQPRSAWTHELDLRP
WREAF

Sequences:

>Translated_245_residues
MSAPTGACLVVGVGDGLGSAIARAFAAEGLAVCMTRRPRHLEALEALAQDIRDAGGRAHAYGVDARSEDEMAALFAAIER
DVGPLEVVVFNIGANVRFPIRETTARVFHKVWEMACFAGFLAGREAARVMVPRGRGTILFTGATASVRGRDGFAAFAAAK
HGLRAVAQSMARELGPEGIHVAHVVIDGGIDGTFIRENRPDAEAALARDEILRPEDVALNYVALHRQPRSAWTHELDLRP
WREAF
>Mature_244_residues
SAPTGACLVVGVGDGLGSAIARAFAAEGLAVCMTRRPRHLEALEALAQDIRDAGGRAHAYGVDARSEDEMAALFAAIERD
VGPLEVVVFNIGANVRFPIRETTARVFHKVWEMACFAGFLAGREAARVMVPRGRGTILFTGATASVRGRDGFAAFAAAKH
GLRAVAQSMARELGPEGIHVAHVVIDGGIDGTFIRENRPDAEAALARDEILRPEDVALNYVALHRQPRSAWTHELDLRPW
REAF

Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1790717, Length=202, Percent_Identity=26.2376237623762, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367175, Length=181, Percent_Identity=28.7292817679558, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=167, Percent_Identity=23.9520958083832, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 26332; Mature: 26201

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTGACLVVGVGDGLGSAIARAFAAEGLAVCMTRRPRHLEALEALAQDIRDAGGRAHA
CCCCCCCEEEEECCCCHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHCCCCEEE
YGVDARSEDEMAALFAAIERDVGPLEVVVFNIGANVRFPIRETTARVFHKVWEMACFAGF
EECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHH
LAGREAARVMVPRGRGTILFTGATASVRGRDGFAAFAAAKHGLRAVAQSMARELGPEGIH
HHCCCCCEEEEECCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VAHVVIDGGIDGTFIRENRPDAEAALARDEILRPEDVALNYVALHRQPRSAWTHELDLRP
EEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCHHHHEEHHEEECCCHHHCCCCCCCCC
WREAF
HHHCC
>Mature Secondary Structure 
SAPTGACLVVGVGDGLGSAIARAFAAEGLAVCMTRRPRHLEALEALAQDIRDAGGRAHA
CCCCCCEEEEECCCCHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHCCCCEEE
YGVDARSEDEMAALFAAIERDVGPLEVVVFNIGANVRFPIRETTARVFHKVWEMACFAGF
EECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHH
LAGREAARVMVPRGRGTILFTGATASVRGRDGFAAFAAAKHGLRAVAQSMARELGPEGIH
HHCCCCCEEEEECCCCEEEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VAHVVIDGGIDGTFIRENRPDAEAALARDEILRPEDVALNYVALHRQPRSAWTHELDLRP
EEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCHHHHEEHHEEECCCHHHCCCCCCCCC
WREAF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751271 [H]