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The map label for this gene is arsC [H]

Identifier: 197105659

GI number: 197105659

Start: 2482014

End: 2482472

Strand: Reverse

Name: arsC [H]

Synonym: PHZ_c2196

Alternate gene names: 197105659

Gene position: 2482472-2482014 (Counterclockwise)

Preceding gene: 197105660

Following gene: 197105658

Centisome position: 62.12

GC content: 70.81

Gene sequence:

>459_bases
ATGACGTCCGATCCGGAGGCGCGGCTGCCCGATGCGGTCCTCTTCGCCTGCAATCTCAATCGGGTCCGTTCGCCCATGGC
CGAGGCGCTGCTCAAGCGCCTGCTGGGCGACAGGGTCTTCGTCGACAGCTGCGGGCTGAGGCCCCCCGGGAACGAGGACG
ACGGCGGGGTCGATCCCCTGGCGGCCGAGGTGATGCGCGAGGTGGGCCTGGACCTGGCGGAGCATCGCGCCAAGACCTTC
GACGAGCTCGACGACGACTCGTTCGATCTCGTCATCTCCCTGACGCCGGAGGCGCAACACCGGGCGGTCGAGATGGCGCG
GGGGCGGGCCTCCGAGATCGAGTACTGGCCCACGTTCGACCCCACCCTGGCCGAGGGCTCCCGCGAGAGCCGGCTGGAGG
CCTATCGCCAGGTCCGGGATGCGCTGGCCGCGCGAATCGCCGAGCGGTTCCGGCGTTGA

Upstream 100 bases:

>100_bases
TGCAGACCCGGCTCAAGGGCAAGATCGAGACCGATCTCGACACGGCGCGGCGGCTGTTCACGCTGATCTGCGCGCTGCAT
TGGCGGGGTTGACCGGCCCG

Downstream 100 bases:

>100_bases
ACTCAGAACCATCGACCTGCCGCCTTCGGATGCGTTATATTCGCTGTGGAGAATCCGGCTCGCGGCCCCGAGGCGCGAGC
CGTCGTTTTATCTCGATCAG

Product: phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTSDPEARLPDAVLFACNLNRVRSPMAEALLKRLLGDRVFVDSCGLRPPGNEDDGGVDPLAAEVMREVGLDLAEHRAKTF
DELDDDSFDLVISLTPEAQHRAVEMARGRASEIEYWPTFDPTLAEGSRESRLEAYRQVRDALAARIAERFRR

Sequences:

>Translated_152_residues
MTSDPEARLPDAVLFACNLNRVRSPMAEALLKRLLGDRVFVDSCGLRPPGNEDDGGVDPLAAEVMREVGLDLAEHRAKTF
DELDDDSFDLVISLTPEAQHRAVEMARGRASEIEYWPTFDPTLAEGSRESRLEAYRQVRDALAARIAERFRR
>Mature_151_residues
TSDPEARLPDAVLFACNLNRVRSPMAEALLKRLLGDRVFVDSCGLRPPGNEDDGGVDPLAAEVMREVGLDLAEHRAKTFD
ELDDDSFDLVISLTPEAQHRAVEMARGRASEIEYWPTFDPTLAEGSRESRLEAYRQVRDALAARIAERFRR

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17042; Mature: 16911

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDPEARLPDAVLFACNLNRVRSPMAEALLKRLLGDRVFVDSCGLRPPGNEDDGGVDPL
CCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHH
AAEVMREVGLDLAEHRAKTFDELDDDSFDLVISLTPEAQHRAVEMARGRASEIEYWPTFD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
PTLAEGSRESRLEAYRQVRDALAARIAERFRR
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSDPEARLPDAVLFACNLNRVRSPMAEALLKRLLGDRVFVDSCGLRPPGNEDDGGVDPL
CCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHH
AAEVMREVGLDLAEHRAKTFDELDDDSFDLVISLTPEAQHRAVEMARGRASEIEYWPTFD
HHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
PTLAEGSRESRLEAYRQVRDALAARIAERFRR
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]