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The map label for this gene is degU [H]

Identifier: 197105564

GI number: 197105564

Start: 2357661

End: 2358341

Strand: Reverse

Name: degU [H]

Synonym: PHZ_c2101

Alternate gene names: 197105564

Gene position: 2358341-2357661 (Counterclockwise)

Preceding gene: 197105565

Following gene: 197105563

Centisome position: 59.01

GC content: 72.1

Gene sequence:

>681_bases
ATGGGCGTCGGCGCGGGGGCTGGAGGCGGCAGGACCCATCAGGTGCTCCTGGTGGAGGACGAGCGGGCGATCCGCGAGCG
TCTGGCGGCGGCCCTGTCCGAGCCGGGCGACTGCGCGGTCTCGACCGCGGCGACCCTCGCCGAGGGGCGCAGGCTCCTGG
AGGCGCGCGCCTTCGACCTGATCGTCGCCGACATTCGGCTGCCCGACGGCCTGGCCATCGACCTGCTGGCCGAGGCGCGG
GAACGCTATCCGCAGGTGGAGATCCTGGTGATCTCGGTCCTCGGCGACGAGACCACCATCCTGGCGGCCATCGCGGCCGG
CGCCTCGGGCTACATCCTGAAGGACGCGCTGCCCGAGGACGTCCATGCGACCGCGCTCGAGGTGCTGGCGGGAGGCTCGC
CCATCTCCCCCTCGATCGCCCGGTTCATCGTCAAGCGCGCCCGCGCCGAAAGCGGCGCGCGTCCCGCCCCCGTGCAGGAG
GCGCCCCACCTGACCCCGCGCGAGCTGGACATCCTCTGGGGCATCGCCAAGGGACTGACCTACAACGAGATCGCCGACCG
GCTCGGCCTCTCGCGCCACACCGTTCCCAGCCACATCAAGGCCATCTATCGCAAGCTCCAGGTCGCGACCCGAGGCGAGG
CGGTCTACGAGGCGGTCCAGTGCGGCCTGATCCGGATCTGA

Upstream 100 bases:

>100_bases
TGGTCCCATATTCATGGGGTGGCCCGAGCCCGCCGGCTGCGGCTAAGCTTGCGCCATGGCGGGGGACGAGGCAGTGGGCG
CCGGGGCGGCCGGGGCCGGA

Downstream 100 bases:

>100_bases
GCGGCGGGTCCGCCTCGACGGCGGCATGGCGCCAGGCGATCGCCCTCGGCTGGATGATCGCGGTCCTGGCGCTGCTGGGC
GTGGCGAGCATGCTGACCGC

Product: transcriptional regulator,LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGVGAGAGGGRTHQVLLVEDERAIRERLAAALSEPGDCAVSTAATLAEGRRLLEARAFDLIVADIRLPDGLAIDLLAEAR
ERYPQVEILVISVLGDETTILAAIAAGASGYILKDALPEDVHATALEVLAGGSPISPSIARFIVKRARAESGARPAPVQE
APHLTPRELDILWGIAKGLTYNEIADRLGLSRHTVPSHIKAIYRKLQVATRGEAVYEAVQCGLIRI

Sequences:

>Translated_226_residues
MGVGAGAGGGRTHQVLLVEDERAIRERLAAALSEPGDCAVSTAATLAEGRRLLEARAFDLIVADIRLPDGLAIDLLAEAR
ERYPQVEILVISVLGDETTILAAIAAGASGYILKDALPEDVHATALEVLAGGSPISPSIARFIVKRARAESGARPAPVQE
APHLTPRELDILWGIAKGLTYNEIADRLGLSRHTVPSHIKAIYRKLQVATRGEAVYEAVQCGLIRI
>Mature_225_residues
GVGAGAGGGRTHQVLLVEDERAIRERLAAALSEPGDCAVSTAATLAEGRRLLEARAFDLIVADIRLPDGLAIDLLAEARE
RYPQVEILVISVLGDETTILAAIAAGASGYILKDALPEDVHATALEVLAGGSPISPSIARFIVKRARAESGARPAPVQEA
PHLTPRELDILWGIAKGLTYNEIADRLGLSRHTVPSHIKAIYRKLQVATRGEAVYEAVQCGLIRI

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=32.8358208955224, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=32.8358208955224, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786747, Length=154, Percent_Identity=31.1688311688312, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786911, Length=208, Percent_Identity=31.7307692307692, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23960; Mature: 23829

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVGAGAGGGRTHQVLLVEDERAIRERLAAALSEPGDCAVSTAATLAEGRRLLEARAFDL
CCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHE
IVADIRLPDGLAIDLLAEARERYPQVEILVISVLGDETTILAAIAAGASGYILKDALPED
EEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEECCCCCCH
VHATALEVLAGGSPISPSIARFIVKRARAESGARPAPVQEAPHLTPRELDILWGIAKGLT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
YNEIADRLGLSRHTVPSHIKAIYRKLQVATRGEAVYEAVQCGLIRI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GVGAGAGGGRTHQVLLVEDERAIRERLAAALSEPGDCAVSTAATLAEGRRLLEARAFDL
CCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHE
IVADIRLPDGLAIDLLAEARERYPQVEILVISVLGDETTILAAIAAGASGYILKDALPED
EEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEECCCCCCH
VHATALEVLAGGSPISPSIARFIVKRARAESGARPAPVQEAPHLTPRELDILWGIAKGLT
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
YNEIADRLGLSRHTVPSHIKAIYRKLQVATRGEAVYEAVQCGLIRI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]