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The map label for this gene is cysH [H]

Identifier: 197105503

GI number: 197105503

Start: 2283818

End: 2284561

Strand: Reverse

Name: cysH [H]

Synonym: PHZ_c2040

Alternate gene names: 197105503

Gene position: 2284561-2283818 (Counterclockwise)

Preceding gene: 197105504

Following gene: 197105502

Centisome position: 57.17

GC content: 70.7

Gene sequence:

>744_bases
ATGAGCCTGGCCTACGACGCCGCACGCAGCGACACCCTGGCCGCCCGCCTCGACGCCGAGCTGCGCCGGGCGCATCCGCG
CACGGTGATCGAGGCGGCGCTGGAGACCTTCGGCGACAAGCTGGCCCTGGTCTCCTCGTTCGGGGCCGAATCCGCGGTGC
TGCTGCACATCGCCTCCAGGGTGGACCCCGCCATCCCGGTGCTGTTCCTCGACACCGGCATGCTGTTCGGCCAGACGCTG
GACTACCGCAAGCAGCTCGCCGCCCGCCTGGGCCTGACCGACGTGCGCGACCTGCGCCCCGCCTACCAGGACCTGGCGAC
CACCGATCCGCAGAACAAGCTGTGGCGCACTGACACCGACGCCTGCTGCCACATCCGCAAGGTCCTGCCGCTCGACCGGG
CGCTGGAGGGTTTCGAGGCCTGGGTCACCGGCCGCAAGCGCTTCCACGGCGGCGACCGCCTGAACCTGCCCGTGGTCGAG
CCCTCCGACGGGAAGGTGAAGTTCAACCCGCTCGCCAACTGGACAAGGGAAGATCTCGAGGCCTATGCCGCCGAGAACGA
CCTGCCGGCGCATCCGCTGGTCGCCCAGGGCTTCGCCTCGATCGGCTGCTGGCCCTGCACCCAGCCGGTGGAGGAGGGCG
AGGACGTCCGCGCCGGGCGCTGGAAAGGGTTGGACAAGACCGAGTGCGGCATACATCTGGTGCGCGCGCCGGGGGCCGCG
AACAACGTGGGCGGCGACATCTGA

Upstream 100 bases:

>100_bases
GCTCGGGCGCCCAACAGTGGGAGGCCGCCACCCGCCGCTTCCGGCACGTCTACCAGCGCGCGGCCGACGATCGCGAACCC
GCCTTCGTGGAGCGGGACTC

Downstream 100 bases:

>100_bases
TCGCCGGGATAGAAAGCTGATGAACGCCGTGACCGCCGCGCAACCGGCCGCCAAAGCCTCGAGCGCCTTCTTCGTCGAGA
CCGTGACCTGGGTCCAGCAC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSLAYDAARSDTLAARLDAELRRAHPRTVIEAALETFGDKLALVSSFGAESAVLLHIASRVDPAIPVLFLDTGMLFGQTL
DYRKQLAARLGLTDVRDLRPAYQDLATTDPQNKLWRTDTDACCHIRKVLPLDRALEGFEAWVTGRKRFHGGDRLNLPVVE
PSDGKVKFNPLANWTREDLEAYAAENDLPAHPLVAQGFASIGCWPCTQPVEEGEDVRAGRWKGLDKTECGIHLVRAPGAA
NNVGGDI

Sequences:

>Translated_247_residues
MSLAYDAARSDTLAARLDAELRRAHPRTVIEAALETFGDKLALVSSFGAESAVLLHIASRVDPAIPVLFLDTGMLFGQTL
DYRKQLAARLGLTDVRDLRPAYQDLATTDPQNKLWRTDTDACCHIRKVLPLDRALEGFEAWVTGRKRFHGGDRLNLPVVE
PSDGKVKFNPLANWTREDLEAYAAENDLPAHPLVAQGFASIGCWPCTQPVEEGEDVRAGRWKGLDKTECGIHLVRAPGAA
NNVGGDI
>Mature_246_residues
SLAYDAARSDTLAARLDAELRRAHPRTVIEAALETFGDKLALVSSFGAESAVLLHIASRVDPAIPVLFLDTGMLFGQTLD
YRKQLAARLGLTDVRDLRPAYQDLATTDPQNKLWRTDTDACCHIRKVLPLDRALEGFEAWVTGRKRFHGGDRLNLPVVEP
SDGKVKFNPLANWTREDLEAYAAENDLPAHPLVAQGFASIGCWPCTQPVEEGEDVRAGRWKGLDKTECGIHLVRAPGAAN
NVGGDI

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=223, Percent_Identity=32.2869955156951, Blast_Score=108, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325425, Length=227, Percent_Identity=33.4801762114537, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27053; Mature: 26922

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAYDAARSDTLAARLDAELRRAHPRTVIEAALETFGDKLALVSSFGAESAVLLHIASR
CCCCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHH
VDPAIPVLFLDTGMLFGQTLDYRKQLAARLGLTDVRDLRPAYQDLATTDPQNKLWRTDTD
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCH
ACCHIRKVLPLDRALEGFEAWVTGRKRFHGGDRLNLPVVEPSDGKVKFNPLANWTREDLE
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCCCHHHHH
AYAAENDLPAHPLVAQGFASIGCWPCTQPVEEGEDVRAGRWKGLDKTECGIHLVRAPGAA
HHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NNVGGDI
CCCCCCC
>Mature Secondary Structure 
SLAYDAARSDTLAARLDAELRRAHPRTVIEAALETFGDKLALVSSFGAESAVLLHIASR
CCCCCHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHH
VDPAIPVLFLDTGMLFGQTLDYRKQLAARLGLTDVRDLRPAYQDLATTDPQNKLWRTDTD
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCH
ACCHIRKVLPLDRALEGFEAWVTGRKRFHGGDRLNLPVVEPSDGKVKFNPLANWTREDLE
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCCCCCCHHHHH
AYAAENDLPAHPLVAQGFASIGCWPCTQPVEEGEDVRAGRWKGLDKTECGIHLVRAPGAA
HHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEECCCCC
NNVGGDI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA