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The map label for this gene is rlmL [H]

Identifier: 197105360

GI number: 197105360

Start: 2122683

End: 2123708

Strand: Direct

Name: rlmL [H]

Synonym: PHZ_c1897

Alternate gene names: 197105360

Gene position: 2122683-2123708 (Clockwise)

Preceding gene: 197105354

Following gene: 197105361

Centisome position: 53.12

GC content: 72.61

Gene sequence:

>1026_bases
GTGGCAAGCCTACGTTGCGGCAGGCGCCCCGCAACTCGCCAGACGGGCGCCCGGCTGACGGTGGGCCGGCCGGTGGGCTG
GACGCGCGCGGCGGCTTGCGCTTCAAGGCGGGCCATGAGCCGCCCGACTGTCGCCGACGCGCCCGGCGTGATGCGCACCG
AAGGCTGGGCGGACTACGCCCTGCTGGACTCCGGCGGCGGCCGCAAGCTGGAGCGCTACGGCCCCTACACCGTCGTGCGG
CCCGAGCCGCAGTGCCTGTGGACGCCCCGCAAGCCCGAGCTGTGGGACCAGGCCGACGCGGTCTTCGATCCCACCGACGA
GGAGGACGCCGGCCGCTGGCGGTTCAGCGGGCAGCCGAAAGAGGCCTGGCCGCTGGCCTGGCGCGAGGTGAGGTTCCTGG
GCCGGTTCACCGCCTTCCGGCACCTGGCCTTCTTTCCCGAGCAGGCGGCGAACTGGGCGTTCCTGGACGAGCGGGTGCGC
GCCCACGCCGGATCGGCCGGATCGGACGGACCGCCGAGGGTCCTGAACCTGTTCGGCTACACCGGCGTCGCCAGCCTGGT
GATGGCCGCCGCGGGCGCGGCGGTGACCCACGTGGACGCCTCCAAGAAGGCGGTCGCCTGGGCGCGCGAGAACGCCGAGG
CCTCCAAGCTGTCGGACCGGCCGATCCGCTGGATCGTCGAGGACGCCCGCCGCTACGTGCAGCGCGAGGTGCGGCGCGGT
TCGAAGTACGACGGCATCATCCTGGACCCGCCCAAGTACGGCCGCGGACCCGACGGCCAGGTGTGGCGGCTGTTCGAGGA
CCTGCCTGAACTTGCCGGGCTATGCGCTGAACTTCTTTCGGAAAACGCCTCGTTCCTGATCCTCAACGCCTATGCCGAGC
GGATCTCGGGCGCGGCGCTGTCGGGCCTGCTGGCTGAGAAGCTCGCGGGCCGCGGCGGGCGGATCGACTGGGGCGAGCTG
GCGCTGGTGGAGGACGGCGGGGATCGGCAGGTCGGCATGAGCTTCTACGGGCGCTGGTCGCGATGA

Upstream 100 bases:

>100_bases
CCTTGCGCGCCGATCGGCGCGTGGTGGTCCCCACAGCAGTCACGGTTACTCTAGTTCCCCAAGCTCCCCTTGGAGAACAC
CGGACCCCAAATCGACACCG

Downstream 100 bases:

>100_bases
GGGCCGTCACCTCGCTGACCAACCCCACGGTCAAGGCGGTCCGCGCTCTTCACCTGCGCAAGGACCGCGACGAGACCGGC
CTGTTCCTGGCCGAGGGCCT

Product: SAM dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MASLRCGRRPATRQTGARLTVGRPVGWTRAAACASRRAMSRPTVADAPGVMRTEGWADYALLDSGGGRKLERYGPYTVVR
PEPQCLWTPRKPELWDQADAVFDPTDEEDAGRWRFSGQPKEAWPLAWREVRFLGRFTAFRHLAFFPEQAANWAFLDERVR
AHAGSAGSDGPPRVLNLFGYTGVASLVMAAAGAAVTHVDASKKAVAWARENAEASKLSDRPIRWIVEDARRYVQREVRRG
SKYDGIILDPPKYGRGPDGQVWRLFEDLPELAGLCAELLSENASFLILNAYAERISGAALSGLLAEKLAGRGGRIDWGEL
ALVEDGGDRQVGMSFYGRWSR

Sequences:

>Translated_341_residues
MASLRCGRRPATRQTGARLTVGRPVGWTRAAACASRRAMSRPTVADAPGVMRTEGWADYALLDSGGGRKLERYGPYTVVR
PEPQCLWTPRKPELWDQADAVFDPTDEEDAGRWRFSGQPKEAWPLAWREVRFLGRFTAFRHLAFFPEQAANWAFLDERVR
AHAGSAGSDGPPRVLNLFGYTGVASLVMAAAGAAVTHVDASKKAVAWARENAEASKLSDRPIRWIVEDARRYVQREVRRG
SKYDGIILDPPKYGRGPDGQVWRLFEDLPELAGLCAELLSENASFLILNAYAERISGAALSGLLAEKLAGRGGRIDWGEL
ALVEDGGDRQVGMSFYGRWSR
>Mature_340_residues
ASLRCGRRPATRQTGARLTVGRPVGWTRAAACASRRAMSRPTVADAPGVMRTEGWADYALLDSGGGRKLERYGPYTVVRP
EPQCLWTPRKPELWDQADAVFDPTDEEDAGRWRFSGQPKEAWPLAWREVRFLGRFTAFRHLAFFPEQAANWAFLDERVRA
HAGSAGSDGPPRVLNLFGYTGVASLVMAAAGAAVTHVDASKKAVAWARENAEASKLSDRPIRWIVEDARRYVQREVRRGS
KYDGIILDPPKYGRGPDGQVWRLFEDLPELAGLCAELLSENASFLILNAYAERISGAALSGLLAEKLAGRGGRIDWGELA
LVEDGGDRQVGMSFYGRWSR

Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]

COG id: COG1092

COG function: function code R; Predicted SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 THUMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR000241
- InterPro:   IPR017244
- InterPro:   IPR019614
- InterPro:   IPR004114 [H]

Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]

EC number: =2.1.1.173 [H]

Molecular weight: Translated: 37693; Mature: 37562

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLRCGRRPATRQTGARLTVGRPVGWTRAAACASRRAMSRPTVADAPGVMRTEGWADYA
CCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEE
LLDSGGGRKLERYGPYTVVRPEPQCLWTPRKPELWDQADAVFDPTDEEDAGRWRFSGQPK
EEECCCCCCHHHCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
EAWPLAWREVRFLGRFTAFRHLAFFPEQAANWAFLDERVRAHAGSAGSDGPPRVLNLFGY
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TGVASLVMAAAGAAVTHVDASKKAVAWARENAEASKLSDRPIRWIVEDARRYVQREVRRG
HHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC
SKYDGIILDPPKYGRGPDGQVWRLFEDLPELAGLCAELLSENASFLILNAYAERISGAAL
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SGLLAEKLAGRGGRIDWGELALVEDGGDRQVGMSFYGRWSR
HHHHHHHHCCCCCCCCCCCEEEEECCCCCEECHHHHCCCCC
>Mature Secondary Structure 
ASLRCGRRPATRQTGARLTVGRPVGWTRAAACASRRAMSRPTVADAPGVMRTEGWADYA
CCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEE
LLDSGGGRKLERYGPYTVVRPEPQCLWTPRKPELWDQADAVFDPTDEEDAGRWRFSGQPK
EEECCCCCCHHHCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
EAWPLAWREVRFLGRFTAFRHLAFFPEQAANWAFLDERVRAHAGSAGSDGPPRVLNLFGY
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TGVASLVMAAAGAAVTHVDASKKAVAWARENAEASKLSDRPIRWIVEDARRYVQREVRRG
HHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC
SKYDGIILDPPKYGRGPDGQVWRLFEDLPELAGLCAELLSENASFLILNAYAERISGAAL
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
SGLLAEKLAGRGGRIDWGELALVEDGGDRQVGMSFYGRWSR
HHHHHHHHCCCCCCCCCCCEEEEECCCCCEECHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA