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The map label for this gene is ytfL [C]

Identifier: 197105327

GI number: 197105327

Start: 2090970

End: 2092277

Strand: Reverse

Name: ytfL [C]

Synonym: PHZ_c1864

Alternate gene names: 197105327

Gene position: 2092277-2090970 (Counterclockwise)

Preceding gene: 197105328

Following gene: 197105325

Centisome position: 52.36

GC content: 72.55

Gene sequence:

>1308_bases
ATGCTGCTCCTTGCGACCACCGTCGTCTTCCTGCTGATCCTCCTCAACGGCCTGTTCGCCATGTCCGAGCTGGCCGTCGT
CTCCTCCCGACGCGCGCGCCTGCAGGGCCGAGCCGAGCGCGGCGACCGCGGGGCGCGGGCCGCCCTGCGGCTCGCCGAGG
AGCCCACGCGCTTCCTGTCGGCCGTGCAGGTCGGCATCACCCTGATCGGCATCCTGGCCGGCGCCTTCGGCCAGGCCACC
ATCGCCGGCGAGCTGGACACGCGGCTGGAGACGATCGCCTGGCTGGCCCCCTGGTCCGAGCAGATCGCCACCGGCGTGGT
CGTCGTGCTGCTGACCTACTTCTCGCTGATCCTGGGCGAGCTGGTGCCCAAGCGCCTGGCGCTGATCCATCCCGAGGCCA
TCGCCGCCATCGTGGCGCGCCCGCTGGCGGTGATGGCCAAGGCGATGGGGCCGTTCGTGACCCTGCTGACCTTCTCCACC
GCCACGGTGCTGGGCCTGCTGCGCGTGCGCGACCGCGACGGCACCGCCGTGACCCAGGAGGAGGTGGAGTCGGTCCTCGC
CGAGGGCACGGGCGCCGGCGTCATCGAGCCCCAGGAGGAGGCCATGATGCACGAGGTCATGCGCCTGGGGGACCGGCCGG
TGCGGGTGGCCATGACGCCGCGGATGGACGTCTACTGGGTCTCGGCCGAAGCCGACGCGGCGGCCCTGCGCGAGGAGGTG
CGGGCCTGCCCCTATTCGCGGTTCGTGCTGGTCAAGGGCCAGGACTTCGACAGCCCGCTGGGCGTGGTGCACAAGCGCGA
CGTGGCCGACGCCCTGCTGGCCGGCGGGCCGCTCGACCTGTCGGCCCTGGCCCAGGAGCCGCTCTACATCCCCGAGACCA
CCTCGATGCTGCGGGCGCTGGAGCAGTTCAAGGCGTCCAAGAACCACATGGCCTTCGTGGTCGACGAGTTCGGCGGGCTG
GAGGGCATCCTCACCCCCACCGACCTCCTGGAGATGATCGCCGGCGACCTGCCCGAGGAGCACGACAGTCCCGCCGCGGC
CATCGCCGCCCTGCCGGACGGCTCGTTCCTGGTGGACGGCCGGGTCGACATCGTCGAGCTCAACGAGGCGCTGGAGACCG
ACTTCGAGGCCGGCTCGTACCACACCGTCGCGGGCCTGGTGCTGGACCGGCTCGAGCGCCTGCCCGAGCCGGGCGAGGTC
GTGCGCATCGGCCGCTTCGAGGCCGAGGTGCTGCAGATGGACGCCCGCCGCATCGACAAGATCCGCCTGCGGCCCCTGCC
GGGCGCCCGGCGGGAGCCCGGAGTCTAG

Upstream 100 bases:

>100_bases
TTCGGCCGAAGGCGTAGGCGCGACGAACGGCGTCGCGTCCGGGCGCGGGGGGCGCTAGGCTTGTGGCGGGGCGCTTTCGC
CTCGCCATCCTGTCCGGACC

Downstream 100 bases:

>100_bases
GGCGCCAGCCTAGGGCGCCCTCCTAGAACGCCCGGGCCTCGGCGGCCGGCGCGCGCGCTCCGGGCTCGGCCGGGCCGACC
AGCGCCGTCACGTCCGCCAC

Product: CBS domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MLLLATTVVFLLILLNGLFAMSELAVVSSRRARLQGRAERGDRGARAALRLAEEPTRFLSAVQVGITLIGILAGAFGQAT
IAGELDTRLETIAWLAPWSEQIATGVVVVLLTYFSLILGELVPKRLALIHPEAIAAIVARPLAVMAKAMGPFVTLLTFST
ATVLGLLRVRDRDGTAVTQEEVESVLAEGTGAGVIEPQEEAMMHEVMRLGDRPVRVAMTPRMDVYWVSAEADAAALREEV
RACPYSRFVLVKGQDFDSPLGVVHKRDVADALLAGGPLDLSALAQEPLYIPETTSMLRALEQFKASKNHMAFVVDEFGGL
EGILTPTDLLEMIAGDLPEEHDSPAAAIAALPDGSFLVDGRVDIVELNEALETDFEAGSYHTVAGLVLDRLERLPEPGEV
VRIGRFEAEVLQMDARRIDKIRLRPLPGARREPGV

Sequences:

>Translated_435_residues
MLLLATTVVFLLILLNGLFAMSELAVVSSRRARLQGRAERGDRGARAALRLAEEPTRFLSAVQVGITLIGILAGAFGQAT
IAGELDTRLETIAWLAPWSEQIATGVVVVLLTYFSLILGELVPKRLALIHPEAIAAIVARPLAVMAKAMGPFVTLLTFST
ATVLGLLRVRDRDGTAVTQEEVESVLAEGTGAGVIEPQEEAMMHEVMRLGDRPVRVAMTPRMDVYWVSAEADAAALREEV
RACPYSRFVLVKGQDFDSPLGVVHKRDVADALLAGGPLDLSALAQEPLYIPETTSMLRALEQFKASKNHMAFVVDEFGGL
EGILTPTDLLEMIAGDLPEEHDSPAAAIAALPDGSFLVDGRVDIVELNEALETDFEAGSYHTVAGLVLDRLERLPEPGEV
VRIGRFEAEVLQMDARRIDKIRLRPLPGARREPGV
>Mature_435_residues
MLLLATTVVFLLILLNGLFAMSELAVVSSRRARLQGRAERGDRGARAALRLAEEPTRFLSAVQVGITLIGILAGAFGQAT
IAGELDTRLETIAWLAPWSEQIATGVVVVLLTYFSLILGELVPKRLALIHPEAIAAIVARPLAVMAKAMGPFVTLLTFST
ATVLGLLRVRDRDGTAVTQEEVESVLAEGTGAGVIEPQEEAMMHEVMRLGDRPVRVAMTPRMDVYWVSAEADAAALREEV
RACPYSRFVLVKGQDFDSPLGVVHKRDVADALLAGGPLDLSALAQEPLYIPETTSMLRALEQFKASKNHMAFVVDEFGGL
EGILTPTDLLEMIAGDLPEEHDSPAAAIAALPDGSFLVDGRVDIVELNEALETDFEAGSYHTVAGLVLDRLERLPEPGEV
VRIGRFEAEVLQMDARRIDKIRLRPLPGARREPGV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=364, Percent_Identity=27.4725274725275, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=29.03981264637, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082033, Length=336, Percent_Identity=33.0357142857143, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=28.1622911694511, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788119, Length=261, Percent_Identity=28.3524904214559, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786879, Length=262, Percent_Identity=24.8091603053435, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47020; Mature: 47020

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLATTVVFLLILLNGLFAMSELAVVSSRRARLQGRAERGDRGARAALRLAEEPTRFLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHH
AVQVGITLIGILAGAFGQATIAGELDTRLETIAWLAPWSEQIATGVVVVLLTYFSLILGE
HHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVPKRLALIHPEAIAAIVARPLAVMAKAMGPFVTLLTFSTATVLGLLRVRDRDGTAVTQE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
EVESVLAEGTGAGVIEPQEEAMMHEVMRLGDRPVRVAMTPRMDVYWVSAEADAAALREEV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHH
RACPYSRFVLVKGQDFDSPLGVVHKRDVADALLAGGPLDLSALAQEPLYIPETTSMLRAL
HHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHH
EQFKASKNHMAFVVDEFGGLEGILTPTDLLEMIAGDLPEEHDSPAAAIAALPDGSFLVDG
HHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEECC
RVDIVELNEALETDFEAGSYHTVAGLVLDRLERLPEPGEVVRIGRFEAEVLQMDARRIDK
CEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHH
IRLRPLPGARREPGV
EEECCCCCCCCCCCC
>Mature Secondary Structure
MLLLATTVVFLLILLNGLFAMSELAVVSSRRARLQGRAERGDRGARAALRLAEEPTRFLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHH
AVQVGITLIGILAGAFGQATIAGELDTRLETIAWLAPWSEQIATGVVVVLLTYFSLILGE
HHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LVPKRLALIHPEAIAAIVARPLAVMAKAMGPFVTLLTFSTATVLGLLRVRDRDGTAVTQE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
EVESVLAEGTGAGVIEPQEEAMMHEVMRLGDRPVRVAMTPRMDVYWVSAEADAAALREEV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCHHHHHHHHH
RACPYSRFVLVKGQDFDSPLGVVHKRDVADALLAGGPLDLSALAQEPLYIPETTSMLRAL
HHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHH
EQFKASKNHMAFVVDEFGGLEGILTPTDLLEMIAGDLPEEHDSPAAAIAALPDGSFLVDG
HHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEECC
RVDIVELNEALETDFEAGSYHTVAGLVLDRLERLPEPGEVVRIGRFEAEVLQMDARRIDK
CEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHH
IRLRPLPGARREPGV
EEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]