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The map label for this gene is clpX [H]

Identifier: 197105277

GI number: 197105277

Start: 2031743

End: 2033005

Strand: Reverse

Name: clpX [H]

Synonym: PHZ_c1814

Alternate gene names: 197105277

Gene position: 2033005-2031743 (Counterclockwise)

Preceding gene: 197105279

Following gene: 197105276

Centisome position: 50.87

GC content: 65.48

Gene sequence:

>1263_bases
ATGACGAAGGCCGCCAGCGGAGATTCGAAGAGCACGCTGTATTGCTCTTTCTGCGGCAAGAGCCAGCACGAAGTCCGCAA
GCTGATCGCGGGCCCGACAGTGTTCATCTGCGATGAATGCGTCGAACTGTGCATGGACATCATCCGCGAAGAGCACAAGA
TCTCCTTCGTCAAGTCGAAGGACGGGGTGCCGACCCCCAAGGAGATCCGCGAGGTCCTCGACGACTACGTGATCGGCCAG
GACCACGCCAAGAAGGTCCTCTCGGTCGCCGTCCACAACCACTACAAGCGCCTGAACCACGCGACGAAGAACAACGACGT
CGAGCTGGGCAAGGCCAACATCCTGCTGATCGGTCCCACCGGCACCGGCAAGACACTGCTGGCCCAGACGCTGGCCCGAA
TCATCGACGTGCCGTTCACCGTGGCCGACGCCACGACCCTGACCGAGGCGGGCTACGTCGGCGAGGACGTCGAGAACATC
ATCCTGAAGCTGCTGCAGGCGGCCGACTACAACGTCGAACGCGCGCAGCGCGGCATCGTCTACATCGACGAGGTCGACAA
GATCAGCCGCAAGTCGGACAACCCCTCGATCACCCGCGACGTGTCGGGCGAGGGCGTCCAGCAGGCGCTGCTGAAGATCA
TGGAAGGCACCGTGGCCTCGGTGCCCCCGCAGGGCGGCCGCAAGCATCCGCAGCAGGAGTTCCTGCAGGTCGACACGACC
AACATCCTGTTCATCTGCGGCGGCGCCTTCGCCGGGCTCGAGAAGATCATCTCGGCGCGCGGCCAGGGCACCTCGATCGG
CTTCGGCGCCAAGGTGGCCGATCCGGACGAGCGCCGCACGGGCGAGATCTTCCGCCAGGTGGAGCCGGACGACCTGCTGC
GCTTCGGCCTGATCCCCGAGTTCATCGGCCGCCTGCCGGTCATCGCGACCCTGGACGACCTGGACGAGAAGGCCCTGGTG
AAGATCCTCACCGAGCCGAAGAACGCCTTCGTGAAGCAGTACGTCCGCCTCTTCGAGATGGAGAACGTCGGCCTGACCTT
CACCGAGGACGCCCTGATGGCCGTCGCCCGCAAGGCGATCCAGCGCAAGACCGGCGCGCGCGGCCTGCGCTCGATCCTGG
AAGGCGTCCTGCTCGACACCATGTACGAGCTGCCGACCTACGACGGCGTCGAGGAAGTGGTGGTCAACGCCGAGGTCATC
GAAGGCCGGGCCCAGCCGCTGATCATCTACGCCGAGCGCCGCGACAAGGGCGGCGCGGCGTAA

Upstream 100 bases:

>100_bases
TATTCTGCATTGATAGGGCGGACACGCCCCCCGCCAGCGTCAAGGGGTGCGAGGCAGGCCAGGCGATCGGCCAGCGTCGT
CGAGAGAGTGAGACAAGACC

Downstream 100 bases:

>100_bases
GCCCTCCGCCACCGAAGGAATAGCGAGGCCCCGCAGGCGACTGCGGGGCCTTTTGACTTTCGGCGGGCAATGCAGGCTTG
ATAGAACAGCGGTATCCGGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSKDGVPTPKEIREVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPTGTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPEFIGRLPVIATLDDLDEKALV
KILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAIQRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVI
EGRAQPLIIYAERRDKGGAA

Sequences:

>Translated_420_residues
MTKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSKDGVPTPKEIREVLDDYVIGQ
DHAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPTGTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPEFIGRLPVIATLDDLDEKALV
KILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAIQRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVI
EGRAQPLIIYAERRDKGGAA
>Mature_419_residues
TKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSKDGVPTPKEIREVLDDYVIGQD
HAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPTGTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPEFIGRLPVIATLDDLDEKALVK
ILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAIQRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVIE
GRAQPLIIYAERRDKGGAA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=338, Percent_Identity=52.9585798816568, Blast_Score=328, Evalue=5e-90,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=70.1204819277108, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=45.2830188679245, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=327, Percent_Identity=45.8715596330275, Blast_Score=280, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=327, Percent_Identity=45.8715596330275, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=39.440203562341, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.8906882591093, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=411, Percent_Identity=39.1727493917275, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=49.2211838006231, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=49.2211838006231, Blast_Score=303, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46079; Mature: 45948

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSK
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
DGVPTPKEIREVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECCC
GTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPE
EEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
FIGRLPVIATLDDLDEKALVKILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAI
HHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHH
QRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVIEGRAQPLIIYAERRDKGGAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
TKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSK
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECC
DGVPTPKEIREVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECCC
GTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCEECCCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHEECCC
NILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPE
EEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
FIGRLPVIATLDDLDEKALVKILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAI
HHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHH
QRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVIEGRAQPLIIYAERRDKGGAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10322004 [H]