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The map label for this gene is dtpT [H]

Identifier: 197105272

GI number: 197105272

Start: 2023894

End: 2025297

Strand: Reverse

Name: dtpT [H]

Synonym: PHZ_c1809

Alternate gene names: 197105272

Gene position: 2025297-2023894 (Counterclockwise)

Preceding gene: 197105273

Following gene: 197105271

Centisome position: 50.68

GC content: 69.87

Gene sequence:

>1404_bases
ATGACCGCGACGAGCGTCGCCCGCGACGGCGACAAGGCCTTCCTGGGCCACCCGAAGGCGCTGGGCTACCTGGCCTTCTC
CGAAGCCTGGGAGCGCTTCTCGTACTACGGGATGCAGTCGCTGCTGGTCCTCTACATGGTCAAGCAGCTGCTGCTGACGC
CGCATGTCGAGGCGATCGCCGGCTTTGAGACCTTCCGGGCGATCATCGGCGCCATCTACGGCCTGCCGGGCGACGCCTCG
ACCCAGCAGGTCGCCTCCACGATCTTCGGCCTCTACACCAGCCTGGTGTACCTGACGCCGATCGCCGGCGGCTTCATCGC
CGACCGTTTGCTGGGGCGCACGCGCACGATCATCGTCGGCGCGCTGCTGATGTCGGCGGGCCACTTCCTGATGGCCTTCG
ACGCCTCGTTCCTGCTGGCGCTGCTGTGCCTCGTCCTCGGCACCGGCTGCTTCAAGGGCAACATCGCCGGGCAGGTGGGC
GGCCTCTACGCCGAGGGCGACCTGCGCCGGGCCGACGCGTTCCAGATCTTCTATCTCGGCATCAACGCCGGGGTGATCGC
CGCTCCGTTGATCGCCGGCACCCTGGGCGAGGGGGTCGGCTGGCACTACGGCTTCGGCGCGGCCGGCGTCGGCATGCTGA
TCGCCCTGGTGATCTACCTGGCCGGCCGGCGCCACCTGCCGCCGGACCCGCCGCTCCGCCGCGCCGCCAAGGCGGACCGC
CCGAAGCTCAGCGCCCATGACTGGCGCACCATCGCGGTCCTCGTGCTGCTGATCCCGGTGCTCGCGTCCTCGGTGCTGGT
GAACCAGCAGATCTTCAACGCCTACCTCGTCTGGGCCGACCGCAGCGTCGACATGACCCTGTTCGGCCAGCGCCTGCCCA
CCACCTGGCTGATCACTCTCGACAGCATCGTCTCGGTCTCGTTCCTGGCGGGCATGGTCGTCTTCTGGCGGCTCTGGGCG
AAGCGGTTCCGCGAGCCGGACGAGATGGGCAAGCTGACCATCGGCGCGTTCATCTCGGTGCTGGGGGCGCTGTCCCTGGC
GGCGGGCGCGGCCGTCGCGGCGGCCAGCGGGACGCAGGTGAGCCTGTGGTGGCTGATCGCCTTCGAGGTGTTCAACAGCG
CGGCCTTCGCCAACATGCTGCCGGTCTCGCTGGCGCTCTACGCCCGGGCCTCGCCCCCGGCGGTCGTCGGCACCATGATC
GGCGTCTACTACCTGCACCTCGTGATCGGGAACCAGACCGTGGGCGTGCTCGGCACCTTCCTGGAGAAGATGCCCGCCGC
GAACTTCTGGCTGATGCACGCCGGCATCGCGGCCGGCGCGGCCGTGGTGTTCCTGGTGGTCGGCCGGTTCTTCGCCCGCC
TGCTCAGCCACGAGGCGGTTGGAGCCGGGCGGACGGCGCACTAG

Upstream 100 bases:

>100_bases
GGGTCGGGGCGGCCGTGCTGTTCGGGCTGATCGGGGTCTGGGTGCTGCTGGCGGCGCTGTTCGGAACGCGCTAGGCCTTG
CCCCAAGGGGAGTAGATTCC

Downstream 100 bases:

>100_bases
AAGCGGCGGGGAGGGCGGCTAGCTCAGCTGGTTAGAGCATCTCGTTTACACCGAGAGGGTCGGGGGTTCGAATCCCTCGC
CGCCCACCAATTCTGAACCG

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIAGFETFRAIIGAIYGLPGDAS
TQQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVGALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVG
GLYAEGDLRRADAFQIFYLGINAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADR
PKLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITLDSIVSVSFLAGMVVFWRLWA
KRFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQVSLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMI
GVYYLHLVIGNQTVGVLGTFLEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH

Sequences:

>Translated_467_residues
MTATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIAGFETFRAIIGAIYGLPGDAS
TQQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVGALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVG
GLYAEGDLRRADAFQIFYLGINAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADR
PKLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITLDSIVSVSFLAGMVVFWRLWA
KRFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQVSLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMI
GVYYLHLVIGNQTVGVLGTFLEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH
>Mature_466_residues
TATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIAGFETFRAIIGAIYGLPGDAST
QQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVGALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVGG
LYAEGDLRRADAFQIFYLGINAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADRP
KLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITLDSIVSVSFLAGMVVFWRLWAK
RFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQVSLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMIG
VYYLHLVIGNQTVGVLGTFLEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=236, Percent_Identity=29.6610169491525, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1790572, Length=257, Percent_Identity=37.7431906614786, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786927, Length=412, Percent_Identity=29.126213592233, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789911, Length=443, Percent_Identity=25.0564334085779, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1787922, Length=260, Percent_Identity=27.6923076923077, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71987453, Length=239, Percent_Identity=26.7782426778243, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639585, Length=236, Percent_Identity=26.271186440678, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639583, Length=236, Percent_Identity=26.271186440678, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639581, Length=236, Percent_Identity=26.271186440678, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571102, Length=242, Percent_Identity=25.2066115702479, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571100, Length=242, Percent_Identity=25.2066115702479, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571098, Length=242, Percent_Identity=25.2066115702479, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49861; Mature: 49730

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50850 MFS ; PS01022 PTR2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIA
CCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GFETFRAIIGAIYGLPGDASTQQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
ALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVGGLYAEGDLRRADAFQIFYLG
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEE
INAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADR
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
PKLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCCEEHH
DSIVSVSFLAGMVVFWRLWAKRFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMIGVYYLHLVIGNQTVGVLGTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIA
CCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GFETFRAIIGAIYGLPGDASTQQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
ALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVGGLYAEGDLRRADAFQIFYLG
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEE
INAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADR
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
PKLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCCEEHH
DSIVSVSFLAGMVVFWRLWAKRFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMIGVYYLHLVIGNQTVGVLGTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
LEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]