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The map label for this gene is nuoD

Identifier: 197105265

GI number: 197105265

Start: 2016930

End: 2018165

Strand: Reverse

Name: nuoD

Synonym: PHZ_c1802

Alternate gene names: 197105265

Gene position: 2018165-2016930 (Counterclockwise)

Preceding gene: 197105266

Following gene: 197105264

Centisome position: 50.5

GC content: 67.39

Gene sequence:

>1236_bases
TTGACCGGCCAGACCGCGCCTGCGGCGCCCGAGGACGCGAACGTCCTGGGCCTGCCCGAGACCAAGGTCCGCAAGTTCAA
CATCAACTTCGGCCCGCAGCACCCGGCGGCGCACGGCGTGCTGCGCCTGGTGCTCGAGCTGGACGGCGAGGTGGTCGAGC
GGGTGGACCCGCACATCGGCCTGCTGCACCGCGGCACCGAGAAGCTGATGGAGGCCCGGCCGTACGCCCAGACGATCCCG
TACTTCGATCGCCTGGACTACGTGGCCCCGATGAACCAGGAGCACGCCTACTGCCTGGCCATCGAGAAGCTGCTCGGCGT
CGAGGTCCCGGTCCGGGGCCTGCTGATCCGCACGCTCTATGACGAGATCGGCCGCATCCTGAATCACCTGCTGAACGTCA
CGACGCAGGCCATGGACGTCGGCGCGCTCACGCCCCCGCTGTGGGGCTTCGAGGAGCGCGAGAAGCTGATGATCTTCTAC
GAGCGCGCCTCGGGCGCCCGCCTGCACGCGAACTACTACCGCGTCGGCGGCGTGCGGCAGGACCTGCCCCCCGAGCTCGT
GCAGGACATCTCGGACTGGTGCGACGCCTTCCCGAAGATCCTCGACGACATTGAGGGCCTGATCACCGACAACCGCATCT
TCAAGCAGCGCAACGTCGACATCGGCGTGGTGACCAAGGAAGAGGCCATCGCCTGGGGCTTCTCGGGCGTCATGGTGCGC
GGCTCGGGCATCCCCTGGGACCTGCGCCGCAGCCAGCCCTACGCGCTCTACTCCGAGATGGAGTTCGACATCCCGCTGGG
CGTGAACGGCGACTGCTACGACCGCTACCTCTGCCGGATGCAGGAGATGCGGGAGTCCACCAAGATCATGAAGCAGTGCT
GCGAGCGCCTGCTGAAGACGTCGGGCCCCGTGCTGGTGGACGACCACAAGGTCTCGCCGCCCAGGCGCGGCGAGATGAAG
CGCTCGATGGAGGCGCTCATCCACCACTTCAAGCTCTACACCGAGGGCTACCGGACCCCGCCGGGCGACGTCTACGCCTG
CGTCGAGGCGCCGAAGGGCGAGTTCGGCGTCTATCTGGTCAGCAACGGCACCAACAAGCCGTACCGCTGCAAGATCCGCG
CGCCGGGCTATCCGCACCTGCAGGCGATGGACTGGATGAACCGCGGCCACATGCTGGCGGACGTCTCTGCCATCCTGGGC
TCGCTGGACATCGTGTTCGGGGAAATCGACCGGTGA

Upstream 100 bases:

>100_bases
TGGAGTGGCGCAACTGGGACTTCCTCTCGCCGTGGGAAGGGGTGGAGCGCGGCTTCGCGCCGATCCTGCCCGGCGACGAG
AAGGGTGAGGAGGCCAAGTC

Downstream 100 bases:

>100_bases
CGGCGCCCGCGACCCTTTCGCCGGCCGACCTGGTCCAGGGCCAGCTCGACGCCTACAACGCCCAGGACCTGGACGCCTTC
TGCGCCTTCTACGCGGACGA

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARPYAQTIP
YFDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLYDEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFY
ERASGARLHANYYRVGGVRQDLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVR
GSGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKTSGPVLVDDHKVSPPRRGEMK
RSMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLVSNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILG
SLDIVFGEIDR

Sequences:

>Translated_411_residues
MTGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARPYAQTIP
YFDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLYDEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFY
ERASGARLHANYYRVGGVRQDLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVR
GSGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKTSGPVLVDDHKVSPPRRGEMK
RSMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLVSNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILG
SLDIVFGEIDR
>Mature_410_residues
TGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARPYAQTIPY
FDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLYDEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFYE
RASGARLHANYYRVGGVRQDLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVRG
SGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKTSGPVLVDDHKVSPPRRGEMKR
SMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLVSNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILGS
LDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=411, Percent_Identity=60.8272506082725, Blast_Score=516, Evalue=1e-146,
Organism=Homo sapiens, GI260898743, Length=405, Percent_Identity=60.2469135802469, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI145693162, Length=385, Percent_Identity=37.1428571428571, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789076, Length=418, Percent_Identity=25.5980861244019, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788832, Length=386, Percent_Identity=26.9430051813472, Blast_Score=114, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17568379, Length=392, Percent_Identity=58.6734693877551, Blast_Score=505, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17555284, Length=392, Percent_Identity=58.9285714285714, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24638644, Length=392, Percent_Identity=62.2448979591837, Blast_Score=527, Evalue=1e-150,
Organism=Drosophila melanogaster, GI221459469, Length=384, Percent_Identity=57.2916666666667, Blast_Score=471, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_PHEZH (B4RCM6)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130642.1
- GeneID:   6791315
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1802
- HOGENOM:   HBG459705
- OMA:   IFYERAC
- ProtClustDB:   PRK06075
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 46545; Mature: 46414

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00535 COMPLEX1_49K; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIG
CCCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCHH
LLHRGTEKLMEARPYAQTIPYFDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLY
HHHHCHHHHHHCCCHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
DEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFYERASGARLHANYYRVGGVRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECEEEECCCCC
DLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEHHHHHHCCCCCEEEE
GSGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKT
CCCCCCCCCCCCCEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGPVLVDDHKVSPPRRGEMKRSMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLV
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEE
SNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILGSLDIVFGEIDR
ECCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure 
TGQTAPAAPEDANVLGLPETKVRKFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIG
CCCCCCCCCCCCCEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCHH
LLHRGTEKLMEARPYAQTIPYFDRLDYVAPMNQEHAYCLAIEKLLGVEVPVRGLLIRTLY
HHHHCHHHHHHCCCHHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
DEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMIFYERASGARLHANYYRVGGVRQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEECEEEECCCCC
DLPPELVQDISDWCDAFPKILDDIEGLITDNRIFKQRNVDIGVVTKEEAIAWGFSGVMVR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEHHHHHHCCCCCEEEE
GSGIPWDLRRSQPYALYSEMEFDIPLGVNGDCYDRYLCRMQEMRESTKIMKQCCERLLKT
CCCCCCCCCCCCCEEEECCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGPVLVDDHKVSPPRRGEMKRSMEALIHHFKLYTEGYRTPPGDVYACVEAPKGEFGVYLV
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEE
SNGTNKPYRCKIRAPGYPHLQAMDWMNRGHMLADVSAILGSLDIVFGEIDR
ECCCCCCEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA