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The map label for this gene is nuoL [H]

Identifier: 197105256

GI number: 197105256

Start: 2007541

End: 2009757

Strand: Reverse

Name: nuoL [H]

Synonym: PHZ_c1793

Alternate gene names: 197105256

Gene position: 2009757-2007541 (Counterclockwise)

Preceding gene: 197105257

Following gene: 197105255

Centisome position: 50.29

GC content: 68.34

Gene sequence:

>2217_bases
ATGGATCCGAAAGTCCTCGTCTCGATCATCCTGTTCGGGCCGCTCGTCGGCGCGATCGTCGCCGGGCTGTTCGGCCGCGC
GATCCCGAGCAAGGTCTCGCAGGCCGTCACCACGGGCCTGCTGTTCCTCTCGGCCGCCCTGTCGTGGGTGGTGTTCGGCC
AGTGGACGTGGGGCGGCCTCGAGCCCTTCACGCTGACCTACGCCCCGTTCATCCACGTCGGCGACTTCGTCTCGAACTGG
TCGTTCCGCCTGGACGGCCTGTCTGCGGTGATGCTGGTGGTGGTCACCAGCGTCTCCTCGCTCGTGCACCTCTATTCGTG
GGGCTACATGGCCGAGGATCCGCACAAGCCGCGGTTCTTCGCCTATCTGTCGCTGTTCACCTTCGCCATGCTGGCGCTGA
TCAGCGCCGCCGACTTCATGCAGCTGTTCTTCGGCTGGGAAGGCGTGGGCCTGGCCAGCTACCTGCTGATCGGCTTCTGG
TTCAAGAAGCCCACGGCCAACGCCGCCTCGATCAAGGCGTTCGTGGTCAACCGGGTCGGCGACTTCGGCTTTGCGCTCGG
CATCATGACCGTGTTCTGGGCCTTCGGCAGCATCCAGTTCGCCGAGATCTTCCCGCAGATGCAGGCCGCCGCCGGCCGCG
CGTGGAGCTTCATCGGCTACGACTGGAACCTCGTGGACCTGGCCTGCGCGCTGCTGTTCGTCGGCGCCATGGGCAAGTCG
GCGCAGTTCTTCCTGCACACCTGGCTGCCCGACGCGATGGAGGGCCCGACGCCCGTGTCGGCCCTGATCCACGCGGCCAC
CATGGTGACCGCCGGCGTCTACATGGTCTGCCTGCTGTCGCCGATGTTCGAGTACGCCCCGGTGGCCAAGAACATCGTCA
CGGTGATCGGCGCGGTGACGGCCCTGTTCGCCGCGACCGTCGGCCTGACCCAGAACGACATCAAGCGGGTGATCGCCTAT
TCGACCTGCTCGCAGCTGGGCTACATGTTCTTCGCCGCGGGCGTGGGCGCCTACCAGGCGGCCATGTTCCACCTGTTCAC
GCACGCCTTCTTCAAGGCCCTGCTGTTCCTGGGCGCCGGTTCGGTGATCCACGGCATGGCGCACGAGCAGGACATGCGCC
GCTACGGCGGCCTGGTGAAGTACCTGCCCGTCACCTACGCGGTGATGACCATCGGCACGATCGCCATCACCGGCCTGGGC
ATCCCGGGCGTGGAGCTGGGCTTCGCCGGCTTCTATTCGAAGGACGCGATCATCCACGCCGCCTACGAGGCGGGCGGGGC
GGGACACCCGATGGGCTACTTCGCCTTCGTGATCGGCATCTTCGTGGCCGGCCTGACCGCCTTCTACTCCTGGCGCCTGG
CGTTCTTCACGTTCAACGGCAGCGCCCGCTGGACCAGCGAGGACCTCGAGCACCACTGGCACAACCGCGACCACGCGCAT
GACGGCCACGACGACCACGCGACCGCGGCCCAGATCGAGACCCACGACGAGCCGCTGGCCGACGATGCCGGTCATGGGCA
CGGACATGGCCACGGCCACGGGCCGCACCTGCCGCACGAGAGCCCCTGGAGCATGCGCCTGCCGCTGATCCTGCTGGCCA
TCGGCGCGGTCTTCGCTGGCATCGCCTTCCACCACCAGTTCATCGGCGACCACAAGGCCGAGTTCTGGAAGGGCGCGATC
TACAACGCTCCGGTCGAGGCCCATGCGGCCGCGCCGGCGGCGCACGCCGAGGCCGCGGCCGATCACGCGGCGGCCAGCGA
GGTCGCCTCGACCGCCGCCGGTCCGATGCCGGGCGAGGACCACGACACCGCCGAGGCGCACCACGCGCCGACCTGGGTGA
TCTGGGCCCCGCTGGTGGCCTCGGTCCTGGGCCTGCTGGTGGCCGCCTACATGTACCTGCTGAAGGAGGGCCTCGGCGCG
CGCCTCGCCGCCCGCGGCGGGCCGCTCTACACCTTCTTCTACAACAAGTGGTTCTTCGACGAGCTCTACGACGCGGTCTT
CGTCCGCGGCGCGAAGTTCCTGGGCGACCTGTTCTGGAAGGGCGGGGACCAGAAGATCATCGACGGCCTGGGTCCGGACG
GCGTCTCGGCGCTGTCGGTCCAGGTCGGCAAGGGCGCCGGCCGGCTGCAGACCGGCTACGTCTACCACTACGCCTTCGTC
ATGCTGCTGGGCGTCGCGGGCCTTCTGACCTACGCCCTGTGGGCCTGGAACGCCTGA

Upstream 100 bases:

>100_bases
CGAGGCCGCCGTGGGCCTGGCGATCCTCGTCACCTTCTTCCGCAACCGCGGCGACATCTCCGTCGACGACGCCTCGATGA
TGAAGGGCTAGGCGCGCCTC

Downstream 100 bases:

>100_bases
GGGGGATAACGACCGATGCCGCTTCTCTCCCTCATCACCTACGCCCCGCTGGTCGGCGTCGCCGGGATCCTGGCGCTGCG
CCTGTTCGGCCGGCCCGACG

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MDPKVLVSIILFGPLVGAIVAGLFGRAIPSKVSQAVTTGLLFLSAALSWVVFGQWTWGGLEPFTLTYAPFIHVGDFVSNW
SFRLDGLSAVMLVVVTSVSSLVHLYSWGYMAEDPHKPRFFAYLSLFTFAMLALISAADFMQLFFGWEGVGLASYLLIGFW
FKKPTANAASIKAFVVNRVGDFGFALGIMTVFWAFGSIQFAEIFPQMQAAAGRAWSFIGYDWNLVDLACALLFVGAMGKS
AQFFLHTWLPDAMEGPTPVSALIHAATMVTAGVYMVCLLSPMFEYAPVAKNIVTVIGAVTALFAATVGLTQNDIKRVIAY
STCSQLGYMFFAAGVGAYQAAMFHLFTHAFFKALLFLGAGSVIHGMAHEQDMRRYGGLVKYLPVTYAVMTIGTIAITGLG
IPGVELGFAGFYSKDAIIHAAYEAGGAGHPMGYFAFVIGIFVAGLTAFYSWRLAFFTFNGSARWTSEDLEHHWHNRDHAH
DGHDDHATAAQIETHDEPLADDAGHGHGHGHGHGPHLPHESPWSMRLPLILLAIGAVFAGIAFHHQFIGDHKAEFWKGAI
YNAPVEAHAAAPAAHAEAAADHAAASEVASTAAGPMPGEDHDTAEAHHAPTWVIWAPLVASVLGLLVAAYMYLLKEGLGA
RLAARGGPLYTFFYNKWFFDELYDAVFVRGAKFLGDLFWKGGDQKIIDGLGPDGVSALSVQVGKGAGRLQTGYVYHYAFV
MLLGVAGLLTYALWAWNA

Sequences:

>Translated_738_residues
MDPKVLVSIILFGPLVGAIVAGLFGRAIPSKVSQAVTTGLLFLSAALSWVVFGQWTWGGLEPFTLTYAPFIHVGDFVSNW
SFRLDGLSAVMLVVVTSVSSLVHLYSWGYMAEDPHKPRFFAYLSLFTFAMLALISAADFMQLFFGWEGVGLASYLLIGFW
FKKPTANAASIKAFVVNRVGDFGFALGIMTVFWAFGSIQFAEIFPQMQAAAGRAWSFIGYDWNLVDLACALLFVGAMGKS
AQFFLHTWLPDAMEGPTPVSALIHAATMVTAGVYMVCLLSPMFEYAPVAKNIVTVIGAVTALFAATVGLTQNDIKRVIAY
STCSQLGYMFFAAGVGAYQAAMFHLFTHAFFKALLFLGAGSVIHGMAHEQDMRRYGGLVKYLPVTYAVMTIGTIAITGLG
IPGVELGFAGFYSKDAIIHAAYEAGGAGHPMGYFAFVIGIFVAGLTAFYSWRLAFFTFNGSARWTSEDLEHHWHNRDHAH
DGHDDHATAAQIETHDEPLADDAGHGHGHGHGHGPHLPHESPWSMRLPLILLAIGAVFAGIAFHHQFIGDHKAEFWKGAI
YNAPVEAHAAAPAAHAEAAADHAAASEVASTAAGPMPGEDHDTAEAHHAPTWVIWAPLVASVLGLLVAAYMYLLKEGLGA
RLAARGGPLYTFFYNKWFFDELYDAVFVRGAKFLGDLFWKGGDQKIIDGLGPDGVSALSVQVGKGAGRLQTGYVYHYAFV
MLLGVAGLLTYALWAWNA
>Mature_738_residues
MDPKVLVSIILFGPLVGAIVAGLFGRAIPSKVSQAVTTGLLFLSAALSWVVFGQWTWGGLEPFTLTYAPFIHVGDFVSNW
SFRLDGLSAVMLVVVTSVSSLVHLYSWGYMAEDPHKPRFFAYLSLFTFAMLALISAADFMQLFFGWEGVGLASYLLIGFW
FKKPTANAASIKAFVVNRVGDFGFALGIMTVFWAFGSIQFAEIFPQMQAAAGRAWSFIGYDWNLVDLACALLFVGAMGKS
AQFFLHTWLPDAMEGPTPVSALIHAATMVTAGVYMVCLLSPMFEYAPVAKNIVTVIGAVTALFAATVGLTQNDIKRVIAY
STCSQLGYMFFAAGVGAYQAAMFHLFTHAFFKALLFLGAGSVIHGMAHEQDMRRYGGLVKYLPVTYAVMTIGTIAITGLG
IPGVELGFAGFYSKDAIIHAAYEAGGAGHPMGYFAFVIGIFVAGLTAFYSWRLAFFTFNGSARWTSEDLEHHWHNRDHAH
DGHDDHATAAQIETHDEPLADDAGHGHGHGHGHGPHLPHESPWSMRLPLILLAIGAVFAGIAFHHQFIGDHKAEFWKGAI
YNAPVEAHAAAPAAHAEAAADHAAASEVASTAAGPMPGEDHDTAEAHHAPTWVIWAPLVASVLGLLVAAYMYLLKEGLGA
RLAARGGPLYTFFYNKWFFDELYDAVFVRGAKFLGDLFWKGGDQKIIDGLGPDGVSALSVQVGKGAGRLQTGYVYHYAFV
MLLGVAGLLTYALWAWNA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=415, Percent_Identity=38.5542168674699, Blast_Score=279, Evalue=8e-75,
Organism=Escherichia coli, GI1788614, Length=459, Percent_Identity=42.483660130719, Blast_Score=308, Evalue=9e-85,
Organism=Escherichia coli, GI1788829, Length=373, Percent_Identity=32.171581769437, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788831, Length=346, Percent_Identity=27.7456647398844, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788827, Length=420, Percent_Identity=27.6190476190476, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788613, Length=344, Percent_Identity=26.453488372093, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693160, Length=359, Percent_Identity=27.0194986072423, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367154, Length=130, Percent_Identity=33.0769230769231, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 79653; Mature: 79653

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]