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The map label for this gene is acdA [H]

Identifier: 197105143

GI number: 197105143

Start: 1884662

End: 1885801

Strand: Reverse

Name: acdA [H]

Synonym: PHZ_c1680

Alternate gene names: 197105143

Gene position: 1885801-1884662 (Counterclockwise)

Preceding gene: 197105144

Following gene: 197105142

Centisome position: 47.19

GC content: 70.09

Gene sequence:

>1140_bases
ATGGACTTCAACCTGACGGAAGATCAGCGGGCGATCGAGGACGCGGCGCGCGCCTTCGCCGCCGCTGAGCTCGCGCCCCA
TTCGGCGCGCTGGGACGAGGAGAAGCACTTACCCGTCGACGTCATGCGCAAGGCGGCCGAGCTGGGCTTCGCCGGCCTCT
ACGTGCGCGACGACGTGGGCGGCTCGGCGCTCTCCCGGCTCGACGCCTCCATCGTCTTCGAGCAGCTCTCCTACGGCGAC
GTCGCGGTGGCGGCCTTCATCTCGATCCACAACATGGCTTCGTGGATGATCGACCGGTTCGGCTCGGAGGAGCTGCGCCG
GCGGTTCCTGCCCAGGCTGACGACGATGGAGCTCATCGCCTCGTACTGCCTGACCGAGCCGGGCGCCGGCTCGGACGCGG
CCTCGCTGCAGACCAGCGCGCGCAGCGATGGCGGCGAATACGTCCTGAACGGCTCCAAGGCCTTCATCTCGGGCGCCGGG
ACTTCCGACGTCTACGTCGTGATGGCCCGGACGGGCGGGGAGGGCGCCGGCGGCGTCTCCACCTTCGTCGTCGAGAAGGA
TACGCCCGGTCTCTCCTTCGGCGCCCAGGAGCGGAAGATGGGCTGGAACGCCCAGCCGACCGCCCTGGTCCACTTCGACA
ACTGCCGCGTGCCCGAGGCGAACCGGGTCGGCGACGAGGGCCAGGGGTTCAAGATCGCCATGGCCGGACTCGACGGCGGG
CGGATCAACATCGCCTCGTGCTCGCTGGGCGGGGCGGCGCTGGCCTTCGACACGGCCAAGGCGCACCTCGAGACCCGCAG
GCAGTTCGGCCGGGCGCTGCGCGAGTTCCAGGGTCTGCAGTGGCGCCTCGCCGACATGGCGACCGAGCTGGAGGCGGCGC
GCCTGATGGTCCGCCGCGCCGCCCACGCCCTCGACAACAAGGATCCGAAGGCCACCCAGTACTGCGCCATGGCCAAGCGC
TTCGCGACCGACGCCGGCTTCGAGGTAGCGAACCAGGCGCTGCAGCTGCACGGCGGCTATGGCTACCTGCGCGACTATCC
GCTGGAGCGGATCGTCCGCGACCTGCGCGTCCACCAGATCCTCGAAGGCGCCAACGAGGTCATGCGCGTGATCACCGCCC
GGGAGCTGTTCCGTCCATGA

Upstream 100 bases:

>100_bases
ACCAGATGGTCTGGCGGATGCGCCAGCAGGGCCTTCGGCCCCGGGCCGCTCCCCCAACGGCAGATTGACACCACGTCATG
GGCGGGCGAACTCCCCGCCC

Downstream 100 bases:

>100_bases
GCGAGCCTGAAGTCCTCTGCCGCATCGAAGGCCGCGTCGGGCGCATCACCCTGAACCGGCCGCAGGCGCTGCACGCGCTG
ACGACGCGGATGTGCCGGGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDFNLTEDQRAIEDAARAFAAAELAPHSARWDEEKHLPVDVMRKAAELGFAGLYVRDDVGGSALSRLDASIVFEQLSYGD
VAVAAFISIHNMASWMIDRFGSEELRRRFLPRLTTMELIASYCLTEPGAGSDAASLQTSARSDGGEYVLNGSKAFISGAG
TSDVYVVMARTGGEGAGGVSTFVVEKDTPGLSFGAQERKMGWNAQPTALVHFDNCRVPEANRVGDEGQGFKIAMAGLDGG
RINIASCSLGGAALAFDTAKAHLETRRQFGRALREFQGLQWRLADMATELEAARLMVRRAAHALDNKDPKATQYCAMAKR
FATDAGFEVANQALQLHGGYGYLRDYPLERIVRDLRVHQILEGANEVMRVITARELFRP

Sequences:

>Translated_379_residues
MDFNLTEDQRAIEDAARAFAAAELAPHSARWDEEKHLPVDVMRKAAELGFAGLYVRDDVGGSALSRLDASIVFEQLSYGD
VAVAAFISIHNMASWMIDRFGSEELRRRFLPRLTTMELIASYCLTEPGAGSDAASLQTSARSDGGEYVLNGSKAFISGAG
TSDVYVVMARTGGEGAGGVSTFVVEKDTPGLSFGAQERKMGWNAQPTALVHFDNCRVPEANRVGDEGQGFKIAMAGLDGG
RINIASCSLGGAALAFDTAKAHLETRRQFGRALREFQGLQWRLADMATELEAARLMVRRAAHALDNKDPKATQYCAMAKR
FATDAGFEVANQALQLHGGYGYLRDYPLERIVRDLRVHQILEGANEVMRVITARELFRP
>Mature_379_residues
MDFNLTEDQRAIEDAARAFAAAELAPHSARWDEEKHLPVDVMRKAAELGFAGLYVRDDVGGSALSRLDASIVFEQLSYGD
VAVAAFISIHNMASWMIDRFGSEELRRRFLPRLTTMELIASYCLTEPGAGSDAASLQTSARSDGGEYVLNGSKAFISGAG
TSDVYVVMARTGGEGAGGVSTFVVEKDTPGLSFGAQERKMGWNAQPTALVHFDNCRVPEANRVGDEGQGFKIAMAGLDGG
RINIASCSLGGAALAFDTAKAHLETRRQFGRALREFQGLQWRLADMATELEAARLMVRRAAHALDNKDPKATQYCAMAKR
FATDAGFEVANQALQLHGGYGYLRDYPLERIVRDLRVHQILEGANEVMRVITARELFRP

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=61.4973262032086, Blast_Score=482, Evalue=1e-136,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=37.6, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=35.5437665782493, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=35.5437665782493, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=39.3617021276596, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI4501857, Length=366, Percent_Identity=33.879781420765, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI21361497, Length=355, Percent_Identity=35.4929577464789, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=32.3607427055703, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI76496475, Length=336, Percent_Identity=34.5238095238095, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI4557235, Length=336, Percent_Identity=34.5238095238095, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=32.7380952380952, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=28.2722513089005, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=28.808864265928, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI38505218, Length=362, Percent_Identity=28.4530386740331, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI211971008, Length=378, Percent_Identity=30.6878306878307, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI48976061, Length=378, Percent_Identity=30.6878306878307, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=30.6493506493506, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1786223, Length=375, Percent_Identity=30.1333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082384, Length=293, Percent_Identity=29.3515358361775, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081702, Length=361, Percent_Identity=23.8227146814404, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=53.8666666666667, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=34.9081364829396, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=35.6020942408377, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=35.6955380577428, Blast_Score=248, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=36.4383561643836, Blast_Score=237, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=34.4262295081967, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=35.7954545454545, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=34.0314136125654, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=37.0748299319728, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=285, Percent_Identity=35.0877192982456, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=39.4736842105263, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=33.0909090909091, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=28.3068783068783, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17505929, Length=356, Percent_Identity=28.9325842696629, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=27.2727272727273, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=346, Percent_Identity=30.9248554913295, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=33.0472103004292, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=185, Percent_Identity=29.1891891891892, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=339, Percent_Identity=26.2536873156342, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=339, Percent_Identity=26.2536873156342, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=37.6344086021505, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=34.5646437994723, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=37.6, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=34.8404255319149, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=32.9842931937173, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=33.0357142857143, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=30.2872062663185, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41290; Mature: 41290

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNLTEDQRAIEDAARAFAAAELAPHSARWDEEKHLPVDVMRKAAELGFAGLYVRDDVG
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCC
GSALSRLDASIVFEQLSYGDVAVAAFISIHNMASWMIDRFGSEELRRRFLPRLTTMELIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHH
SYCLTEPGAGSDAASLQTSARSDGGEYVLNGSKAFISGAGTSDVYVVMARTGGEGAGGVS
HHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCE
TFVVEKDTPGLSFGAQERKMGWNAQPTALVHFDNCRVPEANRVGDEGQGFKIAMAGLDGG
EEEEECCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCC
RINIASCSLGGAALAFDTAKAHLETRRQFGRALREFQGLQWRLADMATELEAARLMVRRA
EEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AHALDNKDPKATQYCAMAKRFATDAGFEVANQALQLHGGYGYLRDYPLERIVRDLRVHQI
HHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHH
LEGANEVMRVITARELFRP
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFNLTEDQRAIEDAARAFAAAELAPHSARWDEEKHLPVDVMRKAAELGFAGLYVRDDVG
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCC
GSALSRLDASIVFEQLSYGDVAVAAFISIHNMASWMIDRFGSEELRRRFLPRLTTMELIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHH
SYCLTEPGAGSDAASLQTSARSDGGEYVLNGSKAFISGAGTSDVYVVMARTGGEGAGGVS
HHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCE
TFVVEKDTPGLSFGAQERKMGWNAQPTALVHFDNCRVPEANRVGDEGQGFKIAMAGLDGG
EEEEECCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCC
RINIASCSLGGAALAFDTAKAHLETRRQFGRALREFQGLQWRLADMATELEAARLMVRRA
EEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AHALDNKDPKATQYCAMAKRFATDAGFEVANQALQLHGGYGYLRDYPLERIVRDLRVHQI
HHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHH
LEGANEVMRVITARELFRP
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]