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The map label for this gene is ctaA [H]

Identifier: 197105117

GI number: 197105117

Start: 1861092

End: 1862129

Strand: Reverse

Name: ctaA [H]

Synonym: PHZ_c1654

Alternate gene names: 197105117

Gene position: 1862129-1861092 (Counterclockwise)

Preceding gene: 197105119

Following gene: 197105116

Centisome position: 46.6

GC content: 71.29

Gene sequence:

>1038_bases
GTGCCCATGACTTCATTCCTGCGTTCCGACCGTTCCAAGTCCGTCGCCGTCTGGCTGTGGGGGGTGGCCTTCCTGGTCCT
CGCCATGGTGGTGGTGGGCGGGGCGACCCGGCTGACGGGCTCGGGCCTGTCGATCACCGAATGGAAGCCGGTGACGGGGG
TCATCCCGCCGCTGAGCGATGCGGCCTGGCAGGCCGAGTTCGCCCGCTACCAGGCGATCCCGCAGTACCAGCAGATCAAC
CGGGGCATGAGCCTTCCGCAGTTCCAGGAGATCTACTGGTGGGAATGGGGACACCGGTTCCTGGGGCGGCTGACCGGCCT
CGTCTTCTTCGTCCCCTTCGTCTGGTTCGCGATCCGTCGCGAGATCCCGAAGCGGCTGTTCCTGCGGCTCGCCGGCATCT
TCCTGCTGGGGGCGCTGCAGGGAGTGGTCGGCTGGTGGATGGTGGCGAGCGGCCTGTCGGAGCGGGTCTATGTCGCGCCC
GAGCGGCTGATGGTCCACCTGGGACTCGCCTTCGCCCTGCTGGCCGCCCTGGTCTGGACGGCGCTGGACGCCTGGTCGGG
CGGGGCGCGGCAGACGCTGCCCAGCCCCTGGGGCCGGCGCGCCGCCTGGCTGATGGCGCTGATCTACGTCCAGATCCTGC
TGGGCGCCCTGGTCGCGGGCAACCACGCGGGGCTCGTCTACAACGACTTTCCGCTGATGAACGGGCGGCTCGTGCCCGAG
GACTACGCCGCCACCACCCTGTGGGGGACGCTGGCCCATAGCCAGGGGGCGGTGCAGCTGCATCACCGTCTCGCCGCCTA
CCTGCTGACCGGGGTGGCGATCGCCGTCGGCTGGTCGGCCTGGCGCTCGAACTATCTGGCGCGGGATTCCAAGCTGCTGG
CGGTCGGCGTCGCCGCCGCCGTGGTCCTGCAGGCCTGCCTGGGGGTGGCGACCCTGATGGCCCAGGTCCCGCTGGCGCTC
GGCATCGCCCACCAGGTCGCCGCGGCGGTGGTCCTGGCGCTCGCGACGGCGTTCGCCTGGCGCGTGCGGCGGGTCTGA

Upstream 100 bases:

>100_bases
GGACGCGCGCGGACATGAGGCCGGTGATAGCGGGGTCGCGCTCGTCGCGTAAGACCGATAAACACGGCGCCCAAGTTCGG
CCCCCAAGCTGCGCCACCGC

Downstream 100 bases:

>100_bases
GGCGCAGAAAATCGCGGTATCTCGCTACCGCATACGTTAAGTTATTGAATTAACGGCTTTTCTTCCGCGCACTCGCAAAC
CGGGAGTGTTGACAGCCGGC

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPMTSFLRSDRSKSVAVWLWGVAFLVLAMVVVGGATRLTGSGLSITEWKPVTGVIPPLSDAAWQAEFARYQAIPQYQQIN
RGMSLPQFQEIYWWEWGHRFLGRLTGLVFFVPFVWFAIRREIPKRLFLRLAGIFLLGALQGVVGWWMVASGLSERVYVAP
ERLMVHLGLAFALLAALVWTALDAWSGGARQTLPSPWGRRAAWLMALIYVQILLGALVAGNHAGLVYNDFPLMNGRLVPE
DYAATTLWGTLAHSQGAVQLHHRLAAYLLTGVAIAVGWSAWRSNYLARDSKLLAVGVAAAVVLQACLGVATLMAQVPLAL
GIAHQVAAAVVLALATAFAWRVRRV

Sequences:

>Translated_345_residues
MPMTSFLRSDRSKSVAVWLWGVAFLVLAMVVVGGATRLTGSGLSITEWKPVTGVIPPLSDAAWQAEFARYQAIPQYQQIN
RGMSLPQFQEIYWWEWGHRFLGRLTGLVFFVPFVWFAIRREIPKRLFLRLAGIFLLGALQGVVGWWMVASGLSERVYVAP
ERLMVHLGLAFALLAALVWTALDAWSGGARQTLPSPWGRRAAWLMALIYVQILLGALVAGNHAGLVYNDFPLMNGRLVPE
DYAATTLWGTLAHSQGAVQLHHRLAAYLLTGVAIAVGWSAWRSNYLARDSKLLAVGVAAAVVLQACLGVATLMAQVPLAL
GIAHQVAAAVVLALATAFAWRVRRV
>Mature_344_residues
PMTSFLRSDRSKSVAVWLWGVAFLVLAMVVVGGATRLTGSGLSITEWKPVTGVIPPLSDAAWQAEFARYQAIPQYQQINR
GMSLPQFQEIYWWEWGHRFLGRLTGLVFFVPFVWFAIRREIPKRLFLRLAGIFLLGALQGVVGWWMVASGLSERVYVAPE
RLMVHLGLAFALLAALVWTALDAWSGGARQTLPSPWGRRAAWLMALIYVQILLGALVAGNHAGLVYNDFPLMNGRLVPED
YAATTLWGTLAHSQGAVQLHHRLAAYLLTGVAIAVGWSAWRSNYLARDSKLLAVGVAAAVVLQACLGVATLMAQVPLALG
IAHQVAAAVVLALATAFAWRVRRV

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group [H]

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921985, Length=346, Percent_Identity=34.393063583815, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI17921987, Length=305, Percent_Identity=34.4262295081967, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17536069, Length=357, Percent_Identity=31.9327731092437, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320989, Length=379, Percent_Identity=35.3562005277045, Blast_Score=195, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19922860, Length=351, Percent_Identity=32.7635327635328, Blast_Score=148, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003780 [H]

Pfam domain/function: PF02628 COX15-CtaA [H]

EC number: NA

Molecular weight: Translated: 37795; Mature: 37664

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMTSFLRSDRSKSVAVWLWGVAFLVLAMVVVGGATRLTGSGLSITEWKPVTGVIPPLSD
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCH
AAWQAEFARYQAIPQYQQINRGMSLPQFQEIYWWEWGHRFLGRLTGLVFFVPFVWFAIRR
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIPKRLFLRLAGIFLLGALQGVVGWWMVASGLSERVYVAPERLMVHLGLAFALLAALVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
ALDAWSGGARQTLPSPWGRRAAWLMALIYVQILLGALVAGNHAGLVYNDFPLMNGRLVPE
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCC
DYAATTLWGTLAHSQGAVQLHHRLAAYLLTGVAIAVGWSAWRSNYLARDSKLLAVGVAAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVLQACLGVATLMAQVPLALGIAHQVAAAVVLALATAFAWRVRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMTSFLRSDRSKSVAVWLWGVAFLVLAMVVVGGATRLTGSGLSITEWKPVTGVIPPLSD
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCH
AAWQAEFARYQAIPQYQQINRGMSLPQFQEIYWWEWGHRFLGRLTGLVFFVPFVWFAIRR
HHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIPKRLFLRLAGIFLLGALQGVVGWWMVASGLSERVYVAPERLMVHLGLAFALLAALVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
ALDAWSGGARQTLPSPWGRRAAWLMALIYVQILLGALVAGNHAGLVYNDFPLMNGRLVPE
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCC
DYAATTLWGTLAHSQGAVQLHHRLAAYLLTGVAIAVGWSAWRSNYLARDSKLLAVGVAAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVLQACLGVATLMAQVPLALGIAHQVAAAVVLALATAFAWRVRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA