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The map label for this gene is phbC [H]

Identifier: 197105109

GI number: 197105109

Start: 1854618

End: 1856471

Strand: Direct

Name: phbC [H]

Synonym: PHZ_c1646

Alternate gene names: 197105109

Gene position: 1854618-1856471 (Clockwise)

Preceding gene: 197105104

Following gene: 197105110

Centisome position: 46.41

GC content: 68.55

Gene sequence:

>1854_bases
ATGAGCGAACAGACCCTTCCGAAGGGCGCCAAGGGCAAGACAGCCAAGCCGGCCCAGAAGCCGCCGCTCCCCGAGGAGCC
CCTCGCCGCCATCGACCCCTCGCCCGCCTCCGCCGGACCCGCCGCGCCGGCCTTCGACGCCGCCCAGGGCGCCATCGCCG
AGATGGCGCTGCGCCAGGCCGACCGCCCGTCCGGCCTCTCCCCCGACCCGTTCCACGTGGCCCCCGCCCTGACCGAGGTG
ATGGGCCGCCTGGCCGCCCAGCCCGACCGGCTGATGCGCGCCCAGGCCGACCTCTTCGCGCGCTATCTCGAGCTCTGGCA
GTCGGCCGCCCGGCGGATGGCCGGCGAGACCGTCGAGCCGGTGGCCCAGCCCGCCAAGGGCGACAAGCGCTTCGCCGACC
CCGACTGGACCGAGAATCCGGTCTTCGACATCATCAAGCAGTCGTACCTGCTCACCTCGGGCTGGCTGAACGGCCTCGTC
GCCGACGTGGAAGGCGTCGACCCGATGGAGAAGCGCCGGGTCGAGTTCTTCATGAAGATGCTCACCGACGCCTTCTCGCC
GTCGAACTTCCTGGCCTCCAACCCGGCGGCGCTGAAGGAGGTGATGGCCACCCACGGCGAGAGTCTGGTGCGGGGGATGG
AGAATTTCGCCGCCGACTTGCAGCGCGGCGGCGGCCAGCTCTCGATCGCCCAGACCGACTACGACCGGTTCCGGATCGGA
GAGAACGTGGCGACGGCGCCTGGAAAGGTCGTCTTCCGCAACGATATCATCGAGTTGATCCAGTATTCTCCCGCGACGGA
GCAGGTCTTCGAGATCCCGCTGGTGATCTTCCCGCCCTGGATCAACAAGTTCTACATCCTCGACCTGCGGCCGGAGAACT
CGATGATCCGCTGGCTGGTCGGCCAGGGGATCACGGTCTTCGTCGCCTCCTGGGTCAATCCCACGCCCGAGCTCTCCACG
CGCACCTTCGAGGACTACATGCGCGAGGGGATCTACGCCGGCGCCGCCGCGGCCATGGAGCAGTGCGGCACGCCGCACGT
GAACGCGGTCGGCTACTGCATCGGCGGCACCCTGCTCTCGGCCGCCCTCGCCCACATGGCCGCCAAGGGCGTACAGCCGG
TCGCCTCGGCCACCTTCTTCGCGGCCCAGCAGGATTTCTCCGAGGCCGGCGACCTCCTGCTGTTCACCAACGAGAACTGG
CTGAAGACGCTCGAGCAGAAGATGGACGAGGGCGGCGGCGTGCTCTCGGGCCAGGCCATGGCCGACACCTTCAACGCCCT
GCGCGCCAACGACCTGATCTGGTCGTTCTTCGTGAACAACTACCTGCTTGGCAAGGAGCCCAAGCCGTTCGACCTGCTGT
TCTGGAACTCGGACCAGACACGCATGCCGAAGACCCTGCACCTCTTCTACCTGCGCAAGTTCTACGGCGAGAACGCGCTG
GCGAAGGGCGAGCTCGTGCTGGACGGGGTCAAGCTGAACCTCGGCGACGTGAAGGTCCCGGTCTATGTCCAGTCCTCGAG
GGAGGACCACATCGCCCCGGCCCGCTCGGTGTTCAAGGGCGCCCGGCTGTTCGGCGGCCCGGTGACCTTCACCCTGGCCG
GCTCGGGCCACATCGCCGGGGTCATCAACGCTCCGGCGGCCAACAAGTACCAGCACTGGACGTGCGACCGCCTGCCCGGG
ACTCTCGAGGAATGGCAGGCCGAGGCCAAGGAGGCGCCCGGCTCGTGGTGGCCGCACTGGGCCGAGTGGCTGAAGGCCCG
CTCAGGCAAGATGGTCCCGGCCCGCGATCCGGCGAACGGCAAGCTCAAGCCGATCTGCGACGCCCCCGGGGAGTACGTGA
AGGTCCGCAGCTAG

Upstream 100 bases:

>100_bases
GAAAAGGCGGGCGCGGCGCATTCATCTCTGTCACGCTCTTATGCGATGATCGCCAAAGGCGGAAGAGCGTGCGATCTCTT
TCGGCGACGAGGAAACGCGG

Downstream 100 bases:

>100_bases
GCGCTCCGACGCCCTTCCCGGCGGCGCCGTAACGTACGTTACTAACGTTTAATGCACGCTACCTTGCGTCGCACGCTACC
TGTCGGTACACCAGAGCTCG

Product: poly-beta-hydroxybutyrate polymerase

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSEQTLPKGAKGKTAKPAQKPPLPEEPLAAIDPSPASAGPAAPAFDAAQGAIAEMALRQADRPSGLSPDPFHVAPALTEV
MGRLAAQPDRLMRAQADLFARYLELWQSAARRMAGETVEPVAQPAKGDKRFADPDWTENPVFDIIKQSYLLTSGWLNGLV
ADVEGVDPMEKRRVEFFMKMLTDAFSPSNFLASNPAALKEVMATHGESLVRGMENFAADLQRGGGQLSIAQTDYDRFRIG
ENVATAPGKVVFRNDIIELIQYSPATEQVFEIPLVIFPPWINKFYILDLRPENSMIRWLVGQGITVFVASWVNPTPELST
RTFEDYMREGIYAGAAAAMEQCGTPHVNAVGYCIGGTLLSAALAHMAAKGVQPVASATFFAAQQDFSEAGDLLLFTNENW
LKTLEQKMDEGGGVLSGQAMADTFNALRANDLIWSFFVNNYLLGKEPKPFDLLFWNSDQTRMPKTLHLFYLRKFYGENAL
AKGELVLDGVKLNLGDVKVPVYVQSSREDHIAPARSVFKGARLFGGPVTFTLAGSGHIAGVINAPAANKYQHWTCDRLPG
TLEEWQAEAKEAPGSWWPHWAEWLKARSGKMVPARDPANGKLKPICDAPGEYVKVRS

Sequences:

>Translated_617_residues
MSEQTLPKGAKGKTAKPAQKPPLPEEPLAAIDPSPASAGPAAPAFDAAQGAIAEMALRQADRPSGLSPDPFHVAPALTEV
MGRLAAQPDRLMRAQADLFARYLELWQSAARRMAGETVEPVAQPAKGDKRFADPDWTENPVFDIIKQSYLLTSGWLNGLV
ADVEGVDPMEKRRVEFFMKMLTDAFSPSNFLASNPAALKEVMATHGESLVRGMENFAADLQRGGGQLSIAQTDYDRFRIG
ENVATAPGKVVFRNDIIELIQYSPATEQVFEIPLVIFPPWINKFYILDLRPENSMIRWLVGQGITVFVASWVNPTPELST
RTFEDYMREGIYAGAAAAMEQCGTPHVNAVGYCIGGTLLSAALAHMAAKGVQPVASATFFAAQQDFSEAGDLLLFTNENW
LKTLEQKMDEGGGVLSGQAMADTFNALRANDLIWSFFVNNYLLGKEPKPFDLLFWNSDQTRMPKTLHLFYLRKFYGENAL
AKGELVLDGVKLNLGDVKVPVYVQSSREDHIAPARSVFKGARLFGGPVTFTLAGSGHIAGVINAPAANKYQHWTCDRLPG
TLEEWQAEAKEAPGSWWPHWAEWLKARSGKMVPARDPANGKLKPICDAPGEYVKVRS
>Mature_616_residues
SEQTLPKGAKGKTAKPAQKPPLPEEPLAAIDPSPASAGPAAPAFDAAQGAIAEMALRQADRPSGLSPDPFHVAPALTEVM
GRLAAQPDRLMRAQADLFARYLELWQSAARRMAGETVEPVAQPAKGDKRFADPDWTENPVFDIIKQSYLLTSGWLNGLVA
DVEGVDPMEKRRVEFFMKMLTDAFSPSNFLASNPAALKEVMATHGESLVRGMENFAADLQRGGGQLSIAQTDYDRFRIGE
NVATAPGKVVFRNDIIELIQYSPATEQVFEIPLVIFPPWINKFYILDLRPENSMIRWLVGQGITVFVASWVNPTPELSTR
TFEDYMREGIYAGAAAAMEQCGTPHVNAVGYCIGGTLLSAALAHMAAKGVQPVASATFFAAQQDFSEAGDLLLFTNENWL
KTLEQKMDEGGGVLSGQAMADTFNALRANDLIWSFFVNNYLLGKEPKPFDLLFWNSDQTRMPKTLHLFYLRKFYGENALA
KGELVLDGVKLNLGDVKVPVYVQSSREDHIAPARSVFKGARLFGGPVTFTLAGSGHIAGVINAPAANKYQHWTCDRLPGT
LEEWQAEAKEAPGSWWPHWAEWLKARSGKMVPARDPANGKLKPICDAPGEYVKVRS

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 67571; Mature: 67439

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQTLPKGAKGKTAKPAQKPPLPEEPLAAIDPSPASAGPAAPAFDAAQGAIAEMALRQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
DRPSGLSPDPFHVAPALTEVMGRLAAQPDRLMRAQADLFARYLELWQSAARRMAGETVEP
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAQPAKGDKRFADPDWTENPVFDIIKQSYLLTSGWLNGLVADVEGVDPMEKRRVEFFMKM
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LTDAFSPSNFLASNPAALKEVMATHGESLVRGMENFAADLQRGGGQLSIAQTDYDRFRIG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCC
ENVATAPGKVVFRNDIIELIQYSPATEQVFEIPLVIFPPWINKFYILDLRPENSMIRWLV
CCCCCCCCCEEEHHHHHHHHHCCCCHHHHHCCCEEEECCCCCEEEEEEECCCCCHHHHHH
GQGITVFVASWVNPTPELSTRTFEDYMREGIYAGAAAAMEQCGTPHVNAVGYCIGGTLLS
HCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AALAHMAAKGVQPVASATFFAAQQDFSEAGDLLLFTNENWLKTLEQKMDEGGGVLSGQAM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCEEECCHH
ADTFNALRANDLIWSFFVNNYLLGKEPKPFDLLFWNSDQTRMPKTLHLFYLRKFYGENAL
HHHHHHHHHHHHHHHHHHHCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
AKGELVLDGVKLNLGDVKVPVYVQSSREDHIAPARSVFKGARLFGGPVTFTLAGSGHIAG
CCCCEEEECEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEE
VINAPAANKYQHWTCDRLPGTLEEWQAEAKEAPGSWWPHWAEWLKARSGKMVPARDPANG
EEECCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
KLKPICDAPGEYVKVRS
CCCCCCCCCCCEEEECC
>Mature Secondary Structure 
SEQTLPKGAKGKTAKPAQKPPLPEEPLAAIDPSPASAGPAAPAFDAAQGAIAEMALRQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
DRPSGLSPDPFHVAPALTEVMGRLAAQPDRLMRAQADLFARYLELWQSAARRMAGETVEP
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VAQPAKGDKRFADPDWTENPVFDIIKQSYLLTSGWLNGLVADVEGVDPMEKRRVEFFMKM
HHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LTDAFSPSNFLASNPAALKEVMATHGESLVRGMENFAADLQRGGGQLSIAQTDYDRFRIG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHCC
ENVATAPGKVVFRNDIIELIQYSPATEQVFEIPLVIFPPWINKFYILDLRPENSMIRWLV
CCCCCCCCCEEEHHHHHHHHHCCCCHHHHHCCCEEEECCCCCEEEEEEECCCCCHHHHHH
GQGITVFVASWVNPTPELSTRTFEDYMREGIYAGAAAAMEQCGTPHVNAVGYCIGGTLLS
HCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AALAHMAAKGVQPVASATFFAAQQDFSEAGDLLLFTNENWLKTLEQKMDEGGGVLSGQAM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCEEECCHH
ADTFNALRANDLIWSFFVNNYLLGKEPKPFDLLFWNSDQTRMPKTLHLFYLRKFYGENAL
HHHHHHHHHHHHHHHHHHHCEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCC
AKGELVLDGVKLNLGDVKVPVYVQSSREDHIAPARSVFKGARLFGGPVTFTLAGSGHIAG
CCCCEEEECEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEE
VINAPAANKYQHWTCDRLPGTLEEWQAEAKEAPGSWWPHWAEWLKARSGKMVPARDPANG
EEECCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
KLKPICDAPGEYVKVRS
CCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748438 [H]