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The map label for this gene is aatC [H]

Identifier: 197105107

GI number: 197105107

Start: 1852752

End: 1853972

Strand: Reverse

Name: aatC [H]

Synonym: PHZ_c1644

Alternate gene names: 197105107

Gene position: 1853972-1852752 (Counterclockwise)

Preceding gene: 197105108

Following gene: 197105106

Centisome position: 46.39

GC content: 68.14

Gene sequence:

>1221_bases
ATGACCCCCGAGTTCCACCGGATCCGACGCCTCCCTCCCTACGTCTTCGAGGAGGTCAACCGCATCAAGGCCCGCCTGCG
CGGCCAGGGCGTCGACATCATCGATTTCGGCATGGGCAATCCCGACATGCCGACCCCCAAGCACATCGTCGAGAAGCTGA
TCGAGACGGCCCGGCACCCCAAGGCCGGCCGCTATTCGGCCTCGAAGGGCATTCCCGGCCTGCGCAAGGCCATGGCCGGC
TATTACGGCCGCCGCTTCGGCGTGAAGCTGAACCCCGACACCGAGGTGATCGCCACCCTGGGCTCGAAGGAGGGCTTCGC
CAACCTCGCCCAGGCGCTGACCGCCCCCGGCGACGTGATCGTCTGCCCGAACCCGGCCTATCCGATCCACGCCTACGGCT
TCATCATGGCCGGCGGGGTGATCCGCCACGTGCCGGCCGGCAGCCCCGAGGAATACCTGTCGGGCATCAGCCGGGCGGTG
AAGCACTCGGCCCCGCCGCCGAGCGTGCTGATCGTCAGCTACCCGTCGAACCCGACCGCCCAGTGGGTGGACCTCGACTT
CTACCGCGAGGTCATCTCGCTGGCGAAGAAGCACGACATGCTCGTACTGTCGGACATCGCCTATTCCGAGATCTACTTCG
AGAACAACCCGCCGCCGTCGATCCTGCAGGTCGAGGGCGCGAAGGACATCGCCGTCGAGGTCAACTCGCTGTCCAAGACC
TACGCCATGGCCGGCTGGCGTGTGGGCATGGTGGTGGGCAACGAGCGGATGTGCGCGGCGCTCGCGCGGGTGAAGTCGTA
CCTCGACTACGGCGCCTACACGCCCATCCAGGTGGCCGCCGCCGCGGCGCTGAACGGGCCGCAGGACTGCGTCGAGGAGA
TCCGCCAGATCTACAAGGGCCGCCGGGACTGCCTGGTGGAGTCCATGCGCCGCGCCGGCTGGGACATCCCCGCGCCGCCG
GCCTCGATGTTCGCCTGGGCGCCGCTGCCGGAGCAATATAAGGAAGCCGGCTCCATGCTGTTCTCCAAGCTCCTGGTCGA
GGAAGCCGGCGTCGCCGTCGCCCCGGGCATCGCCTTCGGCGAGTACGGCGAGGGCTATGTGCGCATCGGCCTCGTGGAGA
ACGAGCAGCGGATCCGCCAGGCGGCCCGCAACGTGAAGAAGTTCCTGGCCAACGCGGACGAGATCCTCGGGCGGGCCCAC
AACACCATGGCGGCGCAATGA

Upstream 100 bases:

>100_bases
GAAACCCGGCTTGGCGGACTCCGGCCCGGAGTCTATCGATGCCTGACCCTCAGCTCACCTTGAGGCCGCGCCGGGCAAGC
GCGGCGAGAGCTCCCTGAAC

Downstream 100 bases:

>100_bases
CGGACAGGACCTGGCGCATCGGAGTCGCGGGCCTGGGCACCGTAGGCGCGGGGCTGCTGACGTTCCTGGCCGAGCATCCC
GGCTTCGCCCCCGCGGGCGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTPEFHRIRRLPPYVFEEVNRIKARLRGQGVDIIDFGMGNPDMPTPKHIVEKLIETARHPKAGRYSASKGIPGLRKAMAG
YYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTAPGDVIVCPNPAYPIHAYGFIMAGGVIRHVPAGSPEEYLSGISRAV
KHSAPPPSVLIVSYPSNPTAQWVDLDFYREVISLAKKHDMLVLSDIAYSEIYFENNPPPSILQVEGAKDIAVEVNSLSKT
YAMAGWRVGMVVGNERMCAALARVKSYLDYGAYTPIQVAAAAALNGPQDCVEEIRQIYKGRRDCLVESMRRAGWDIPAPP
ASMFAWAPLPEQYKEAGSMLFSKLLVEEAGVAVAPGIAFGEYGEGYVRIGLVENEQRIRQAARNVKKFLANADEILGRAH
NTMAAQ

Sequences:

>Translated_406_residues
MTPEFHRIRRLPPYVFEEVNRIKARLRGQGVDIIDFGMGNPDMPTPKHIVEKLIETARHPKAGRYSASKGIPGLRKAMAG
YYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTAPGDVIVCPNPAYPIHAYGFIMAGGVIRHVPAGSPEEYLSGISRAV
KHSAPPPSVLIVSYPSNPTAQWVDLDFYREVISLAKKHDMLVLSDIAYSEIYFENNPPPSILQVEGAKDIAVEVNSLSKT
YAMAGWRVGMVVGNERMCAALARVKSYLDYGAYTPIQVAAAAALNGPQDCVEEIRQIYKGRRDCLVESMRRAGWDIPAPP
ASMFAWAPLPEQYKEAGSMLFSKLLVEEAGVAVAPGIAFGEYGEGYVRIGLVENEQRIRQAARNVKKFLANADEILGRAH
NTMAAQ
>Mature_405_residues
TPEFHRIRRLPPYVFEEVNRIKARLRGQGVDIIDFGMGNPDMPTPKHIVEKLIETARHPKAGRYSASKGIPGLRKAMAGY
YGRRFGVKLNPDTEVIATLGSKEGFANLAQALTAPGDVIVCPNPAYPIHAYGFIMAGGVIRHVPAGSPEEYLSGISRAVK
HSAPPPSVLIVSYPSNPTAQWVDLDFYREVISLAKKHDMLVLSDIAYSEIYFENNPPPSILQVEGAKDIAVEVNSLSKTY
AMAGWRVGMVVGNERMCAALARVKSYLDYGAYTPIQVAAAAALNGPQDCVEEIRQIYKGRRDCLVESMRRAGWDIPAPPA
SMFAWAPLPEQYKEAGSMLFSKLLVEEAGVAVAPGIAFGEYGEGYVRIGLVENEQRIRQAARNVKKFLANADEILGRAHN
TMAAQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=22.7848101265823, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=22.7848101265823, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI56713256, Length=418, Percent_Identity=21.7703349282297, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI56713254, Length=422, Percent_Identity=21.8009478672986, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=50.5102040816327, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=26.1333333333333, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=25.1282051282051, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788332, Length=241, Percent_Identity=28.6307053941909, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=23.2098765432099, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=393, Percent_Identity=23.4096692111959, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=393, Percent_Identity=23.4096692111959, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=20.8762886597938, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=22.107969151671, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=22.107969151671, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=22.107969151671, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=22.107969151671, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44458; Mature: 44326

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEFHRIRRLPPYVFEEVNRIKARLRGQGVDIIDFGMGNPDMPTPKHIVEKLIETARHP
CCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KAGRYSASKGIPGLRKAMAGYYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTAPGDVI
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCEE
VCPNPAYPIHAYGFIMAGGVIRHVPAGSPEEYLSGISRAVKHSAPPPSVLIVSYPSNPTA
ECCCCCCCHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
QWVDLDFYREVISLAKKHDMLVLSDIAYSEIYFENNPPPSILQVEGAKDIAVEVNSLSKT
EEEEHHHHHHHHHHHHHCCCEEEECCHHHHEEECCCCCCCEEEECCCCEEEEEHHHHHHH
YAMAGWRVGMVVGNERMCAALARVKSYLDYGAYTPIQVAAAAALNGPQDCVEEIRQIYKG
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
RRDCLVESMRRAGWDIPAPPASMFAWAPLPEQYKEAGSMLFSKLLVEEAGVAVAPGIAFG
HHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCEECCCCEEC
EYGEGYVRIGLVENEQRIRQAARNVKKFLANADEILGRAHNTMAAQ
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPEFHRIRRLPPYVFEEVNRIKARLRGQGVDIIDFGMGNPDMPTPKHIVEKLIETARHP
CCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KAGRYSASKGIPGLRKAMAGYYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTAPGDVI
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCEE
VCPNPAYPIHAYGFIMAGGVIRHVPAGSPEEYLSGISRAVKHSAPPPSVLIVSYPSNPTA
ECCCCCCCHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
QWVDLDFYREVISLAKKHDMLVLSDIAYSEIYFENNPPPSILQVEGAKDIAVEVNSLSKT
EEEEHHHHHHHHHHHHHCCCEEEECCHHHHEEECCCCCCCEEEECCCCEEEEEHHHHHHH
YAMAGWRVGMVVGNERMCAALARVKSYLDYGAYTPIQVAAAAALNGPQDCVEEIRQIYKG
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHC
RRDCLVESMRRAGWDIPAPPASMFAWAPLPEQYKEAGSMLFSKLLVEEAGVAVAPGIAFG
HHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCEECCCCEEC
EYGEGYVRIGLVENEQRIRQAARNVKKFLANADEILGRAHNTMAAQ
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]