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The map label for this gene is sseA [H]

Identifier: 197105092

GI number: 197105092

Start: 1836886

End: 1837725

Strand: Direct

Name: sseA [H]

Synonym: PHZ_c1629

Alternate gene names: 197105092

Gene position: 1836886-1837725 (Clockwise)

Preceding gene: 197105091

Following gene: 197105094

Centisome position: 45.97

GC content: 75.0

Gene sequence:

>840_bases
ATGGATCCTCTGGTTTCCACCGACTGGCTCGACGAACGCCTGCACGACCCGGCGGTCCAGGTGGCGGACGCGACCTGGTA
CATGCCCGGCGAGGGCCGAACGGGCCGCCAGTCGTTCGAGGAGGCGCACATCCCGGGCGCCGTCTTCTTCGACATCGACG
AGGTGGCGGACAAGGACACCGACCTGCCGCACATGCTTCCGTCGGCCGAGGCGTTCGCTCAGGCGGTCGGGGCGCTGGGC
CTGCGGCGGGACGCCGTGGTGGTGGTCTACGACGCCCAGGGCCTGTTCTCGGCCCCGCGCGTGTGGTGGTCGCTGCGGAC
CATGGGCTTTCCGGACGTGCGGGTCCTGGACGGCGGCCTCAAGAAGTGGCGGGCCGAGGGCCGCGTCGTCACCGACGAGC
CGGGCGCGCCGCCGCCGCAGGCGCTCGATGCGGCCTTCCGTCCGGACCTGATCCGCGATCTCGAGGCCGTGCGCGGCCAC
CTGGCGGCCGGCGATGCGCAGGTGCTGGACGCGCGCGCCGCCGCCCGCTTCCGCGGCGAGGCGCCCGAGCCGCGGCCGGG
GCTGCGATCCGGCGCGATGCCGGGCGCCCTGAACCTGCCGTGGCAGGGGCTGGTGAATTCCGACGGCACGCTGAAATCGG
CGGCGGAGCTGCGCGAGGCGTTCACGGCGGCCGGCGTGGACCTGGGCCGGCCCGTGGTGACCACCTGCGGCTCGGGCGTC
AGCGCCGCCCTCCTGGCCTTCGCGCTCGCCCGGCTGGGCCGCGAGGACGTGGCGGTCTACGACGGCTCGTGGACGGAATG
GGGCGGGCGGGCCGACTGCGAGGTCGTCGTCGCCCGCTAG

Upstream 100 bases:

>100_bases
TGCTGTGCGACCACGGCCAGCGCTATCAGTCCAAGATCTTCAACCCCGCGTTCCTGCGCGAGAAGGGCCTGCCCTGCCCG
CCCTGGATGGAGTAGCCGCC

Downstream 100 bases:

>100_bases
CGGACCGGCGGGGCGTACATCAGCCCCGGCTTCGGGGCGGTCCAGAGGGCGTTGAGGCCCCGCTCCAGCTTCAAGGCCGA
GTCGGCGCCAAGGTCGCGGC

Product: rhodanese family protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDPLVSTDWLDERLHDPAVQVADATWYMPGEGRTGRQSFEEAHIPGAVFFDIDEVADKDTDLPHMLPSAEAFAQAVGALG
LRRDAVVVVYDAQGLFSAPRVWWSLRTMGFPDVRVLDGGLKKWRAEGRVVTDEPGAPPPQALDAAFRPDLIRDLEAVRGH
LAAGDAQVLDARAAARFRGEAPEPRPGLRSGAMPGALNLPWQGLVNSDGTLKSAAELREAFTAAGVDLGRPVVTTCGSGV
SAALLAFALARLGREDVAVYDGSWTEWGGRADCEVVVAR

Sequences:

>Translated_279_residues
MDPLVSTDWLDERLHDPAVQVADATWYMPGEGRTGRQSFEEAHIPGAVFFDIDEVADKDTDLPHMLPSAEAFAQAVGALG
LRRDAVVVVYDAQGLFSAPRVWWSLRTMGFPDVRVLDGGLKKWRAEGRVVTDEPGAPPPQALDAAFRPDLIRDLEAVRGH
LAAGDAQVLDARAAARFRGEAPEPRPGLRSGAMPGALNLPWQGLVNSDGTLKSAAELREAFTAAGVDLGRPVVTTCGSGV
SAALLAFALARLGREDVAVYDGSWTEWGGRADCEVVVAR
>Mature_279_residues
MDPLVSTDWLDERLHDPAVQVADATWYMPGEGRTGRQSFEEAHIPGAVFFDIDEVADKDTDLPHMLPSAEAFAQAVGALG
LRRDAVVVVYDAQGLFSAPRVWWSLRTMGFPDVRVLDGGLKKWRAEGRVVTDEPGAPPPQALDAAFRPDLIRDLEAVRGH
LAAGDAQVLDARAAARFRGEAPEPRPGLRSGAMPGALNLPWQGLVNSDGTLKSAAELREAFTAAGVDLGRPVVTTCGSGV
SAALLAFALARLGREDVAVYDGSWTEWGGRADCEVVVAR

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI61835204, Length=281, Percent_Identity=44.1281138790036, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI194473681, Length=281, Percent_Identity=44.1281138790036, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI194473668, Length=281, Percent_Identity=44.1281138790036, Blast_Score=242, Evalue=2e-64,
Organism=Homo sapiens, GI17402865, Length=283, Percent_Identity=43.4628975265018, Blast_Score=223, Evalue=2e-58,
Organism=Escherichia coli, GI87082121, Length=273, Percent_Identity=45.7875457875458, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87081967, Length=241, Percent_Identity=31.1203319502075, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71997283, Length=301, Percent_Identity=27.2425249169435, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17561888, Length=245, Percent_Identity=29.7959183673469, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559150, Length=253, Percent_Identity=26.8774703557312, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543836, Length=218, Percent_Identity=27.0642201834862, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543838, Length=218, Percent_Identity=27.0642201834862, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534702, Length=208, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324825, Length=277, Percent_Identity=33.5740072202166, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 29850; Mature: 29850

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00380 RHODANESE_1 ; PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPLVSTDWLDERLHDPAVQVADATWYMPGEGRTGRQSFEEAHIPGAVFFDIDEVADKDT
CCCCCCCHHHHHHHCCCHHEEECCEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHCCCCC
DLPHMLPSAEAFAQAVGALGLRRDAVVVVYDAQGLFSAPRVWWSLRTMGFPDVRVLDGGL
CCCHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
KKWRAEGRVVTDEPGAPPPQALDAAFRPDLIRDLEAVRGHLAAGDAQVLDARAAARFRGE
HHHHHCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
APEPRPGLRSGAMPGALNLPWQGLVNSDGTLKSAAELREAFTAAGVDLGRPVVTTCGSGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCH
SAALLAFALARLGREDVAVYDGSWTEWGGRADCEVVVAR
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MDPLVSTDWLDERLHDPAVQVADATWYMPGEGRTGRQSFEEAHIPGAVFFDIDEVADKDT
CCCCCCCHHHHHHHCCCHHEEECCEEEECCCCCCCHHHHHHHCCCCEEEEEHHHHCCCCC
DLPHMLPSAEAFAQAVGALGLRRDAVVVVYDAQGLFSAPRVWWSLRTMGFPDVRVLDGGL
CCCHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHH
KKWRAEGRVVTDEPGAPPPQALDAAFRPDLIRDLEAVRGHLAAGDAQVLDARAAARFRGE
HHHHHCCEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
APEPRPGLRSGAMPGALNLPWQGLVNSDGTLKSAAELREAFTAAGVDLGRPVVTTCGSGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCH
SAALLAFALARLGREDVAVYDGSWTEWGGRADCEVVVAR
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]