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The map label for this gene is yyaJ [H]

Identifier: 197105076

GI number: 197105076

Start: 1816803

End: 1818266

Strand: Reverse

Name: yyaJ [H]

Synonym: PHZ_c1613

Alternate gene names: 197105076

Gene position: 1818266-1816803 (Counterclockwise)

Preceding gene: 197105078

Following gene: 197105074

Centisome position: 45.5

GC content: 71.58

Gene sequence:

>1464_bases
ATGCAAGCGAGGGGCGACGTCTTCACCACGGACATTCCGGCCAGGCTCGACCGCCTGCCGTTCAGCCGTTTCCACTGGCT
GGTGGTGTTCGCCCTGGGGATCACCTGGATCCTCGACGGGCTGGAGGTCACCCTCGTGGGGGCGCTGGCCCCCGCCATCG
CCGGCCCTGACGGCCTGGGGCTGACCGCCCAGCAGATCGGCTGGACCGCCAGCGCCTACATCGTCGGCGCTGTGCTGGGG
GCGCTGGTCTTCGGACGGCTCACCGACGCCTTCGGCCGGCGGCGGCTCTTCACCATCACCGTCGTGGTCTACATGCTGGC
CACCATCGCCAGCGGCTTCGCCTGGGACTTCTGGTCGTTCATGTTCTTCCGGTTCCTGACCGGGGCCGGGATCGGCGGGG
AGTACGGCGCCATCAACTCGGCCATCGACGAGCTGATTCCCGCCCGCCGGCGCGGCCAGACGGCCCTGGCCATCAACGGC
AGCTTCTGGGTGGGCGCGGCCCTGGGCGCCGTCGGCTCGCTCGTGGTGCTGGATCCCGAGGTGGTCGATCCCGCCTGGGG
CTGGCGTCTGGCGTTCATCATCGGCGGCCTGCTGGCCCTGATCGTCGTCTTCGTCCGCCGCTACATCCCCGAGAGCCCCC
GCTGGCTCCTCACCCACGGCCGGCCCGAGGAGGCCGAGGCGATCGTGCGCGAGATCGAGGCGCGGGTGGAGCGGCGCACG
GCCCTGCCGCCGATGATCCGTCCGCTGCCCCGGCTGCGCTTCGTGCGGCGCACCCGCACCGACTGGCGCGAGATCTGGCT
CACGCTGGTCCGCCACCACCCGCGGCGCACCGTGCTGGGCTTCGTGCTGATGGCCACCCAGGCCTTCTGCTACAACGCGA
TCTTCTTCACCTACGCCCTGATCCTGACCCGCTTCTACGGCGTCCAGCCGCAGGCCGTGGGCTGGTTCATGCTGCCGTTC
GCCCTCGGCAATTTCCTGGGGCCGCTGCTGCTGGGCCGCCTGTTCGACACCATCGGCCGGCGGACCATGATCTCGGCCAC
CTACGCCCTGGCCGGCGCGCTGCTGTGCCTCACCGGCTGGGGATTCGCCGAGGGGATGCTGACGGCCGAGGCGCAGACGG
CGGCCTGGATGGTGATCTTCTTCTTCGCCTCGGCGGGGGCCAGCGCGGCCTACCTGACCGTCGGCGAGCTGTTCCCGCTG
GAGACCCGGGCCATCACCATCGCGATCTTCTACGCGGTGGGCACCCTGCTGGGCGGCGCCGCCGGGCCTGCGCTGTTCGG
CGCGCTGATCGACACGGGCGAGCGCGGCCAGATCCTCATCGGCTACCTCTTGGGCGGGGGGCTGATGCTGCTGGCCTCGG
TCGTCGCCCTGGCCCTGGGCGTGCGCGCCGAGCGCAAGGGCCTGGAGGAGATCGCCCCGCCGCTCTCGCTCGCCCCCGAG
GACGTTCCCCGGGACGTCCCCTAG

Upstream 100 bases:

>100_bases
TCTCGTCGGAAGCCATCGGCGGGCCTTACACCAGCGGAGGTGAGGAACCCAAGCTCGGCCTTCGCAGTTTGCGTGACCAC
GGGAGCCAGGCAGGTCGGGG

Downstream 100 bases:

>100_bases
GACCTGGGGCGGGGCTGGGCGCTCAGACCGCCCGCCGCACGGGCCCGGCGCGCCGCTCGGACTTCACCATCGCCCAGCCG
TCGCGGGTCAGGAAGTAGGC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MQARGDVFTTDIPARLDRLPFSRFHWLVVFALGITWILDGLEVTLVGALAPAIAGPDGLGLTAQQIGWTASAYIVGAVLG
ALVFGRLTDAFGRRRLFTITVVVYMLATIASGFAWDFWSFMFFRFLTGAGIGGEYGAINSAIDELIPARRRGQTALAING
SFWVGAALGAVGSLVVLDPEVVDPAWGWRLAFIIGGLLALIVVFVRRYIPESPRWLLTHGRPEEAEAIVREIEARVERRT
ALPPMIRPLPRLRFVRRTRTDWREIWLTLVRHHPRRTVLGFVLMATQAFCYNAIFFTYALILTRFYGVQPQAVGWFMLPF
ALGNFLGPLLLGRLFDTIGRRTMISATYALAGALLCLTGWGFAEGMLTAEAQTAAWMVIFFFASAGASAAYLTVGELFPL
ETRAITIAIFYAVGTLLGGAAGPALFGALIDTGERGQILIGYLLGGGLMLLASVVALALGVRAERKGLEEIAPPLSLAPE
DVPRDVP

Sequences:

>Translated_487_residues
MQARGDVFTTDIPARLDRLPFSRFHWLVVFALGITWILDGLEVTLVGALAPAIAGPDGLGLTAQQIGWTASAYIVGAVLG
ALVFGRLTDAFGRRRLFTITVVVYMLATIASGFAWDFWSFMFFRFLTGAGIGGEYGAINSAIDELIPARRRGQTALAING
SFWVGAALGAVGSLVVLDPEVVDPAWGWRLAFIIGGLLALIVVFVRRYIPESPRWLLTHGRPEEAEAIVREIEARVERRT
ALPPMIRPLPRLRFVRRTRTDWREIWLTLVRHHPRRTVLGFVLMATQAFCYNAIFFTYALILTRFYGVQPQAVGWFMLPF
ALGNFLGPLLLGRLFDTIGRRTMISATYALAGALLCLTGWGFAEGMLTAEAQTAAWMVIFFFASAGASAAYLTVGELFPL
ETRAITIAIFYAVGTLLGGAAGPALFGALIDTGERGQILIGYLLGGGLMLLASVVALALGVRAERKGLEEIAPPLSLAPE
DVPRDVP
>Mature_487_residues
MQARGDVFTTDIPARLDRLPFSRFHWLVVFALGITWILDGLEVTLVGALAPAIAGPDGLGLTAQQIGWTASAYIVGAVLG
ALVFGRLTDAFGRRRLFTITVVVYMLATIASGFAWDFWSFMFFRFLTGAGIGGEYGAINSAIDELIPARRRGQTALAING
SFWVGAALGAVGSLVVLDPEVVDPAWGWRLAFIIGGLLALIVVFVRRYIPESPRWLLTHGRPEEAEAIVREIEARVERRT
ALPPMIRPLPRLRFVRRTRTDWREIWLTLVRHHPRRTVLGFVLMATQAFCYNAIFFTYALILTRFYGVQPQAVGWFMLPF
ALGNFLGPLLLGRLFDTIGRRTMISATYALAGALLCLTGWGFAEGMLTAEAQTAAWMVIFFFASAGASAAYLTVGELFPL
ETRAITIAIFYAVGTLLGGAAGPALFGALIDTGERGQILIGYLLGGGLMLLASVVALALGVRAERKGLEEIAPPLSLAPE
DVPRDVP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=249, Percent_Identity=25.7028112449799, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI24308167, Length=478, Percent_Identity=23.6401673640167, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI73695465, Length=285, Percent_Identity=27.0175438596491, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI262399383, Length=190, Percent_Identity=25.7894736842105, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI216548223, Length=251, Percent_Identity=25.4980079681275, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI213021148, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI166064021, Length=184, Percent_Identity=28.2608695652174, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1788068, Length=468, Percent_Identity=26.7094017094017, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788074, Length=432, Percent_Identity=28.2407407407407, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082159, Length=257, Percent_Identity=31.1284046692607, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082231, Length=221, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786229, Length=430, Percent_Identity=25.1162790697674, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081723, Length=385, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789207, Length=394, Percent_Identity=24.1116751269036, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082404, Length=181, Percent_Identity=25.414364640884, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790463, Length=234, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790550, Length=160, Percent_Identity=29.375, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=425, Percent_Identity=25.1764705882353, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71986689, Length=408, Percent_Identity=23.2843137254902, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=408, Percent_Identity=23.2843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565978, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71984734, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323653, Length=368, Percent_Identity=24.4565217391304, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320766, Length=371, Percent_Identity=23.989218328841, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324400, Length=371, Percent_Identity=23.7196765498652, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321886, Length=369, Percent_Identity=23.8482384823848, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321888, Length=381, Percent_Identity=23.3595800524934, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322618, Length=369, Percent_Identity=23.8482384823848, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319956, Length=369, Percent_Identity=23.8482384823848, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322242, Length=372, Percent_Identity=22.8494623655914, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324417, Length=372, Percent_Identity=23.1182795698925, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320552, Length=378, Percent_Identity=23.5449735449735, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319718, Length=355, Percent_Identity=23.3802816901408, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321068, Length=189, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324011, Length=381, Percent_Identity=22.5721784776903, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321100, Length=346, Percent_Identity=24.2774566473988, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640198, Length=480, Percent_Identity=24.7916666666667, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24640196, Length=480, Percent_Identity=24.7916666666667, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24640200, Length=480, Percent_Identity=24.7916666666667, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI62484254, Length=368, Percent_Identity=25.8152173913043, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922874, Length=467, Percent_Identity=23.1263383297645, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221330801, Length=276, Percent_Identity=24.2753623188406, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161080876, Length=232, Percent_Identity=24.5689655172414, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649616, Length=163, Percent_Identity=30.0613496932515, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24649618, Length=333, Percent_Identity=24.9249249249249, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161077756, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330907, Length=178, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52978; Mature: 52978

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARGDVFTTDIPARLDRLPFSRFHWLVVFALGITWILDGLEVTLVGALAPAIAGPDGLG
CCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
LTAQQIGWTASAYIVGAVLGALVFGRLTDAFGRRRLFTITVVVYMLATIASGFAWDFWSF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
MFFRFLTGAGIGGEYGAINSAIDELIPARRRGQTALAINGSFWVGAALGAVGSLVVLDPE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCEEEECCH
VVDPAWGWRLAFIIGGLLALIVVFVRRYIPESPRWLLTHGRPEEAEAIVREIEARVERRT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHC
ALPPMIRPLPRLRFVRRTRTDWREIWLTLVRHHPRRTVLGFVLMATQAFCYNAIFFTYAL
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTRFYGVQPQAVGWFMLPFALGNFLGPLLLGRLFDTIGRRTMISATYALAGALLCLTGW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GFAEGMLTAEAQTAAWMVIFFFASAGASAAYLTVGELFPLETRAITIAIFYAVGTLLGGA
CHHHCCEEECHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCC
AGPALFGALIDTGERGQILIGYLLGGGLMLLASVVALALGVRAERKGLEEIAPPLSLAPE
CHHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCC
DVPRDVP
CCCCCCC
>Mature Secondary Structure
MQARGDVFTTDIPARLDRLPFSRFHWLVVFALGITWILDGLEVTLVGALAPAIAGPDGLG
CCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCC
LTAQQIGWTASAYIVGAVLGALVFGRLTDAFGRRRLFTITVVVYMLATIASGFAWDFWSF
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
MFFRFLTGAGIGGEYGAINSAIDELIPARRRGQTALAINGSFWVGAALGAVGSLVVLDPE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCEEEECCH
VVDPAWGWRLAFIIGGLLALIVVFVRRYIPESPRWLLTHGRPEEAEAIVREIEARVERRT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHC
ALPPMIRPLPRLRFVRRTRTDWREIWLTLVRHHPRRTVLGFVLMATQAFCYNAIFFTYAL
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTRFYGVQPQAVGWFMLPFALGNFLGPLLLGRLFDTIGRRTMISATYALAGALLCLTGW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GFAEGMLTAEAQTAAWMVIFFFASAGASAAYLTVGELFPLETRAITIAIFYAVGTLLGGA
CHHHCCEEECHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCC
AGPALFGALIDTGERGQILIGYLLGGGLMLLASVVALALGVRAERKGLEEIAPPLSLAPE
CHHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHHCCHHHHCCHHHHCCCCCCCCC
DVPRDVP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]