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The map label for this gene is purN [H]

Identifier: 197105064

GI number: 197105064

Start: 1806729

End: 1807340

Strand: Reverse

Name: purN [H]

Synonym: PHZ_c1601

Alternate gene names: 197105064

Gene position: 1807340-1806729 (Counterclockwise)

Preceding gene: 197105065

Following gene: 197105063

Centisome position: 45.23

GC content: 73.2

Gene sequence:

>612_bases
GTGAGAACACGGCCGCTTAAGCTGGGTTTCCTCGCCTCCGCTAACGGCTCCAGCGCCCAGGCGGTGATGGACGCCATCGA
GGGCGGCCGGCTGAACGCCGAGGCCTGCCTGATGGTCAGCAACAACAGGAGCGCGGCGGCGCTGGCGTGGGCGCAGGACC
GGGGCGTGCCGGCGCTGTGCGTGCCCACCGCCGCCGATCCCGAGGCCGCCGATCGCCGCCTGGCCGACGAGATGGCCGCC
CGCGGCGTCGAGCTGATCGTCATGTCCGGCTACCTGCGCCGGCTGGGGCCGGCGGTGCTGGGCCGCTACGGCGGGCGCAT
CCTCAACATCCATCCGGGGCCGCTGCCGGACTTCGGCGGCCAGGGGATGTACGGCCGCCGGGTCCACGAGGCGGTGCTGG
CCGCCGGGCTCGCCGAGAGCAGCATCGTCATCCACCTGGTGGACGAGGAATACGACCACGGGCCCGAGCTCGCGCGCCGC
CGCGTGCCGATCCAGCCCGGCGACACGCCCGAGACGCTGGAGGCGCGGGTGAAGGCCATGGAGCCGGCGTTCTTCGTCGA
AACGCTGCAGCAGATCGCTTCGGGCGCGCTGGAGCTGCCCGATGCCGCTTGA

Upstream 100 bases:

>100_bases
TCGACATGGACTTCGAGACCCTCCGGCGCGAGCTTCCCGAGGGGGTCGAGCCGGCCTACGACGGGCTGACGATCCAACAT
GAGCTGAGAGGCGAAAACGC

Downstream 100 bases:

>100_bases
GCGGCGCGAGTTCCTGGCGGGCGCGGCCGCAGCCGGCCTGGACGGTCCATTGGGAAGCGCGGCGGGAGGCGCAAGGCCGA
TGTACGGACTGATCGGACGC

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MRTRPLKLGFLASANGSSAQAVMDAIEGGRLNAEACLMVSNNRSAAALAWAQDRGVPALCVPTAADPEAADRRLADEMAA
RGVELIVMSGYLRRLGPAVLGRYGGRILNIHPGPLPDFGGQGMYGRRVHEAVLAAGLAESSIVIHLVDEEYDHGPELARR
RVPIQPGDTPETLEARVKAMEPAFFVETLQQIASGALELPDAA

Sequences:

>Translated_203_residues
MRTRPLKLGFLASANGSSAQAVMDAIEGGRLNAEACLMVSNNRSAAALAWAQDRGVPALCVPTAADPEAADRRLADEMAA
RGVELIVMSGYLRRLGPAVLGRYGGRILNIHPGPLPDFGGQGMYGRRVHEAVLAAGLAESSIVIHLVDEEYDHGPELARR
RVPIQPGDTPETLEARVKAMEPAFFVETLQQIASGALELPDAA
>Mature_203_residues
MRTRPLKLGFLASANGSSAQAVMDAIEGGRLNAEACLMVSNNRSAAALAWAQDRGVPALCVPTAADPEAADRRLADEMAA
RGVELIVMSGYLRRLGPAVLGRYGGRILNIHPGPLPDFGGQGMYGRRVHEAVLAAGLAESSIVIHLVDEEYDHGPELARR
RVPIQPGDTPETLEARVKAMEPAFFVETLQQIASGALELPDAA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=204, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI209869995, Length=204, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI209869993, Length=204, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788846, Length=200, Percent_Identity=31.5, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17567511, Length=193, Percent_Identity=31.0880829015544, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24582400, Length=200, Percent_Identity=30.5, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 21532; Mature: 21532

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRPLKLGFLASANGSSAQAVMDAIEGGRLNAEACLMVSNNRSAAALAWAQDRGVPALC
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHHCCCCCEEE
VPTAADPEAADRRLADEMAARGVELIVMSGYLRRLGPAVLGRYGGRILNIHPGPLPDFGG
ECCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
QGMYGRRVHEAVLAAGLAESSIVIHLVDEEYDHGPELARRRVPIQPGDTPETLEARVKAM
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHC
EPAFFVETLQQIASGALELPDAA
CHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRTRPLKLGFLASANGSSAQAVMDAIEGGRLNAEACLMVSNNRSAAALAWAQDRGVPALC
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEHHCCCCCEEE
VPTAADPEAADRRLADEMAARGVELIVMSGYLRRLGPAVLGRYGGRILNIHPGPLPDFGG
ECCCCCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
QGMYGRRVHEAVLAAGLAESSIVIHLVDEEYDHGPELARRRVPIQPGDTPETLEARVKAM
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHC
EPAFFVETLQQIASGALELPDAA
CHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]