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The map label for this gene is merR1 [H]

Identifier: 197104958

GI number: 197104958

Start: 1702657

End: 1703076

Strand: Reverse

Name: merR1 [H]

Synonym: PHZ_c1495

Alternate gene names: 197104958

Gene position: 1703076-1702657 (Counterclockwise)

Preceding gene: 197104974

Following gene: 197104954

Centisome position: 42.62

GC content: 73.81

Gene sequence:

>420_bases
ATGGCGGACACCGCGATACCCATCGGCGAGCTCTCGCGCCGCACCGGCTGCAACATCGAGACGATCCGCTACTACGAGCG
GATCGGCCTCTTGCCCGCCCCGCCGCGACGCGGCCGCTACCGCAGCTATGGGGCAGAAGACGTGGGCCGGCTGGGCTTCG
TGCGCCGGGCCCGCGAGCTGGGCTTCACGCTGGACGAGGTGCGCGCCCTCCTGGGGCTCGCCGCCGGCGGGCAGTCCGCC
TGCGCCGAGGTGCGTGAGCTCGCCGGGTCGCACCTGAAGGACGTGCGGGCGCGGATCGCCGACCTCAGGCGGATGGAACG
GGTGCTCGCCGACTCCGTCCGAGCCTGCGACGCGGGGCTGGACCCCGGCTGTCCGCTCATCCTGGCGCTCTACGCGGAGG
CCCCGGCGAAGCCTGGTTAG

Upstream 100 bases:

>100_bases
GGCCCGCTGCTCGCCGTCATGCCGTCGTCTCCTGGCGCCATGCCGCCCACGATGCCATCTGTAGCGACTACAGACTCAAG
CCCTAATCGGAAGGCTTTGC

Downstream 100 bases:

>100_bases
GTCCAGGCGCGCCGTCGATGCCGTCCAGAACGGCCGTGAACCGCGCCAGCTCGCCGGCCAGGACGGTGCGCTGCGCCGGC
GACAGGCGCTTCTCGCGCAG

Product: transcriptional regulator, MerR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MADTAIPIGELSRRTGCNIETIRYYERIGLLPAPPRRGRYRSYGAEDVGRLGFVRRARELGFTLDEVRALLGLAAGGQSA
CAEVRELAGSHLKDVRARIADLRRMERVLADSVRACDAGLDPGCPLILALYAEAPAKPG

Sequences:

>Translated_139_residues
MADTAIPIGELSRRTGCNIETIRYYERIGLLPAPPRRGRYRSYGAEDVGRLGFVRRARELGFTLDEVRALLGLAAGGQSA
CAEVRELAGSHLKDVRARIADLRRMERVLADSVRACDAGLDPGCPLILALYAEAPAKPG
>Mature_138_residues
ADTAIPIGELSRRTGCNIETIRYYERIGLLPAPPRRGRYRSYGAEDVGRLGFVRRARELGFTLDEVRALLGLAAGGQSAC
AEVRELAGSHLKDVRARIADLRRMERVLADSVRACDAGLDPGCPLILALYAEAPAKPG

Specific function: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury merR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a pote

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=36.2204724409449, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=29.9212598425197, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011794
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15079; Mature: 14947

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTAIPIGELSRRTGCNIETIRYYERIGLLPAPPRRGRYRSYGAEDVGRLGFVRRAREL
CCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GFTLDEVRALLGLAAGGQSACAEVRELAGSHLKDVRARIADLRRMERVLADSVRACDAGL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPGCPLILALYAEAPAKPG
CCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADTAIPIGELSRRTGCNIETIRYYERIGLLPAPPRRGRYRSYGAEDVGRLGFVRRAREL
CCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GFTLDEVRALLGLAAGGQSACAEVRELAGSHLKDVRARIADLRRMERVLADSVRACDAGL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPGCPLILALYAEAPAKPG
CCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536669; 10559175; 2492496; 2305262 [H]