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The map label for this gene is czcC [H]

Identifier: 197104909

GI number: 197104909

Start: 1634584

End: 1635879

Strand: Direct

Name: czcC [H]

Synonym: PHZ_c1444

Alternate gene names: 197104909

Gene position: 1634584-1635879 (Clockwise)

Preceding gene: 197104908

Following gene: 197104910

Centisome position: 40.9

GC content: 74.92

Gene sequence:

>1296_bases
ATGTCCATCTTCCGTCCGAGTTGCGCCCTGGCGCGGCTCCTCGCCGCGCCGCTTCTGGCGGCGCTGGCGCTCGCCTTCGG
CGCTGGCGCCGCTCTGGCCCAGGCGCCCGCGCCGTCCCTGACGCTCACCGACGCGGTGACGCGGGCGCTCGCCGCCGATC
CGTCCACCGCCGCTGCCGAGGCGCGGGTGGAGGCCGCCCGGGCGGCTGCGCGCCAAGCGGGCCTGCGGCCTAACCCCTCG
CTGGGCGTAGAGCTGGAGAACTTCGCAGGCTCGGGCGCCTACTCTGTCTTGGACCGCACCGAAGCCACGGTAAGCTACCA
GCAGACGTTCGAGCGCGGCGGCAAGCGCACGGCGCGCACCGCCGTGGCGGCCGCTGAGATCGAGTTGGTCCACCGGCGCC
AGGAGGTTCGACGCCTGGACCTCATCAAGGAGGTGCAGGTCGCCTACGCCGAAGCGTTGGCCGCCGAAGCGGATCTGCTG
ATCGCCGAGGCCCGGCTGATCGCCGCCCATCGCTCCCAGTCCGACATCTCGCGGCGGGTCCGCAGCGCGCGCGACCCGCT
GTTCGCCGGCGCCCGCGCCGAGACCCTGACCGCTCAGGCCGAGATCGCCCGCGACCAGGCGCGAGAGACGGCGCGCAATG
CGCGAGCGGCGCTCGCCGCGTTCTGGGGCGGCGGCTCCGAGTTCGCGCTCGACCTGGAGACTTTCTTCTTCCGCACCGCG
CCCGCTGCGCCGGCGGCGCCCGCGGAGACCGCGGACCTGGCCCTTCTGGCGGCCACCCGTGACGCCGCCCTGGCGCGGGT
GGAGCTGGAGCGCGCCCGTCAGGTCGCCGACCCCACCCTGCGGGCGGGCGTCCGCTACTTTGGTCAGGGCTCGGACGTCG
CCCTGGTGGTCGGCGGCACGATCCCGCTGCAGCGCTACGACACCAACAAGGCCGGCGTGGAGCGAGCCCTGGCCGAGCGC
AACGCGGCCGAGGCCGACATCGCCGCCGCCCGGGTGCTGCAGGCCCGGGAGGTCGCGCGGCTGCGGGCCAAGCTCGCCGC
CTCTGCGGCCGAGTCCGAGCGGATTCGCGCCGAGGTGATCCCGTCGGCGATCAAGACCGTCGAGCTGGTGCGGGCGGGCT
TCAACCGCGGGGGCTTCCAGTACATCGACGTCACCGAGGCCGAACGCGCCCTGGCCGACGCCCGGGCCCGGCGGGTCGCG
GTGCTGCGCCAGCACCACACCGACCAGGCCGCCCTAGACCGGCTCACCGGCCGCTTCGCCCATCTTGCATCCACGCCTTC
CGCGGAGCCCCGCTGA

Upstream 100 bases:

>100_bases
GCGCCCGGCTAGAACGACCTCCAAAGCCGCTCTCGATCTGAACGCCTGACCGCGCGAGGCCCCGCCACGCGCGCCGTTTC
ACCGTGCTTCGAGAGACCTC

Downstream 100 bases:

>100_bases
TGCTGTCCCACTCTTCCTGGCGCGCTGCGCCGCTCGCCCTGGCGCTGCTCGCCGGCCTTCTCACCGCCTGCGGGGAGCGC
AAGGCGCCCGAGGCGAAAGC

Product: metal ion efflux outer membrane factor protein family

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSIFRPSCALARLLAAPLLAALALAFGAGAALAQAPAPSLTLTDAVTRALAADPSTAAAEARVEAARAAARQAGLRPNPS
LGVELENFAGSGAYSVLDRTEATVSYQQTFERGGKRTARTAVAAAEIELVHRRQEVRRLDLIKEVQVAYAEALAAEADLL
IAEARLIAAHRSQSDISRRVRSARDPLFAGARAETLTAQAEIARDQARETARNARAALAAFWGGGSEFALDLETFFFRTA
PAAPAAPAETADLALLAATRDAALARVELERARQVADPTLRAGVRYFGQGSDVALVVGGTIPLQRYDTNKAGVERALAER
NAAEADIAAARVLQAREVARLRAKLAASAAESERIRAEVIPSAIKTVELVRAGFNRGGFQYIDVTEAERALADARARRVA
VLRQHHTDQAALDRLTGRFAHLASTPSAEPR

Sequences:

>Translated_431_residues
MSIFRPSCALARLLAAPLLAALALAFGAGAALAQAPAPSLTLTDAVTRALAADPSTAAAEARVEAARAAARQAGLRPNPS
LGVELENFAGSGAYSVLDRTEATVSYQQTFERGGKRTARTAVAAAEIELVHRRQEVRRLDLIKEVQVAYAEALAAEADLL
IAEARLIAAHRSQSDISRRVRSARDPLFAGARAETLTAQAEIARDQARETARNARAALAAFWGGGSEFALDLETFFFRTA
PAAPAAPAETADLALLAATRDAALARVELERARQVADPTLRAGVRYFGQGSDVALVVGGTIPLQRYDTNKAGVERALAER
NAAEADIAAARVLQAREVARLRAKLAASAAESERIRAEVIPSAIKTVELVRAGFNRGGFQYIDVTEAERALADARARRVA
VLRQHHTDQAALDRLTGRFAHLASTPSAEPR
>Mature_430_residues
SIFRPSCALARLLAAPLLAALALAFGAGAALAQAPAPSLTLTDAVTRALAADPSTAAAEARVEAARAAARQAGLRPNPSL
GVELENFAGSGAYSVLDRTEATVSYQQTFERGGKRTARTAVAAAEIELVHRRQEVRRLDLIKEVQVAYAEALAAEADLLI
AEARLIAAHRSQSDISRRVRSARDPLFAGARAETLTAQAEIARDQARETARNARAALAAFWGGGSEFALDLETFFFRTAP
AAPAAPAETADLALLAATRDAALARVELERARQVADPTLRAGVRYFGQGSDVALVVGGTIPLQRYDTNKAGVERALAERN
AAEADIAAARVLQAREVARLRAKLAASAAESERIRAEVIPSAIKTVELVRAGFNRGGFQYIDVTEAERALADARARRVAV
LRQHHTDQAALDRLTGRFAHLASTPSAEPR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45687; Mature: 45556

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFRPSCALARLLAAPLLAALALAFGAGAALAQAPAPSLTLTDAVTRALAADPSTAAAE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
ARVEAARAAARQAGLRPNPSLGVELENFAGSGAYSVLDRTEATVSYQQTFERGGKRTART
HHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AVAAAEIELVHRRQEVRRLDLIKEVQVAYAEALAAEADLLIAEARLIAAHRSQSDISRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RSARDPLFAGARAETLTAQAEIARDQARETARNARAALAAFWGGGSEFALDLETFFFRTA
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCC
PAAPAAPAETADLALLAATRDAALARVELERARQVADPTLRAGVRYFGQGSDVALVVGGT
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCC
IPLQRYDTNKAGVERALAERNAAEADIAAARVLQAREVARLRAKLAASAAESERIRAEVI
CCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSAIKTVELVRAGFNRGGFQYIDVTEAERALADARARRVAVLRQHHTDQAALDRLTGRFA
HHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HLASTPSAEPR
HHHCCCCCCCC
>Mature Secondary Structure 
SIFRPSCALARLLAAPLLAALALAFGAGAALAQAPAPSLTLTDAVTRALAADPSTAAAE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
ARVEAARAAARQAGLRPNPSLGVELENFAGSGAYSVLDRTEATVSYQQTFERGGKRTART
HHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AVAAAEIELVHRRQEVRRLDLIKEVQVAYAEALAAEADLLIAEARLIAAHRSQSDISRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
RSARDPLFAGARAETLTAQAEIARDQARETARNARAALAAFWGGGSEFALDLETFFFRTA
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCC
PAAPAAPAETADLALLAATRDAALARVELERARQVADPTLRAGVRYFGQGSDVALVVGGT
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCC
IPLQRYDTNKAGVERALAERNAAEADIAAARVLQAREVARLRAKLAASAAESERIRAEVI
CCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSAIKTVELVRAGFNRGGFQYIDVTEAERALADARARRVAVLRQHHTDQAALDRLTGRFA
HHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HLASTPSAEPR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]