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The map label for this gene is aroB [H]

Identifier: 197104877

GI number: 197104877

Start: 1599196

End: 1600272

Strand: Direct

Name: aroB [H]

Synonym: PHZ_c1411

Alternate gene names: 197104877

Gene position: 1599196-1600272 (Clockwise)

Preceding gene: 197104874

Following gene: 197104878

Centisome position: 40.02

GC content: 74.19

Gene sequence:

>1077_bases
ATGAATGAGGCGCCGCGCGCGCCGGGCGCCCGCGACGGGCGCGACCGGATGAGGTCTGCCGGTGAGCCGCCCTGCTATGC
GGCCCTGGACCTCGGCACCAACAACTGCCGCCTGCTGATCGCCACGCCCTCGCCGACGGGCTTCCGGGTGGTCGAGGCCT
ATTCGCGGATCGTTCGGCTCGGGGAGGGCCTGACCCAGAGCGGACGACTGTCCGAGGCGGCCATGGAGCGGGCCCTGGCC
GCCCTGAAGGTCAGCGCCGAGAAGGTGCGCCGGCGGCGCGTCGTCCGTTTCCGGGCCATCGCCACCCAGGCCTGCCGGAT
CGCCGAGAACGGTCCCGCCTTCGTCGAGCAGGTGGCGAACGAGACGGGCGTGCGGCTCCAGATCATCCCGCCGCAGGAGG
AGGCCCGCCTGTCGGTCACCGGCTGCCTGAACCTGCTGGACCGGGCGATGGAGGCGGCCCTGGTCGTGGACGTGGGCGGC
GGCTCCACCGAGCTCTCCTGGGTGGACCTGAAGGAGGCTCCTCCCGAGGGCATGCCGCCGATCCGGGCGTGGCTCTCGGT
GCCGATCGGCGTGGTCACGCTGGCCGAGCGCTTCCCCGAGGGCGAGGCGGCCACCGAGGGCTGGTTCCGCGCCATGGTCG
AGACGGTGAAGACCGAGATCGCCGCCTTCCGCCGCGCCGATCCGCTGAAGCCGGTGTTCGAGGCCGACCGGGCGCACCTC
GTCGGCACTTCGGGGGCCATCACCAGCCTGGCGGGCATGCACCTCGAACTCCCCCGCTACGACCGCAGCCGCGTGGACGG
CATCTGGATGAGCCGGGACGAGTGCGACGCGGCCGCCGGACGCCTCCTGGCGCTGAACGCCCGCGAGCGCGCCGACCAGC
CGTGCATCGGCCCCGACCGCGCCGACCTGGTGCTGGCCGGCGCCGCGATCCTGCAGGCCGTGCAGGAACTGTGGCCGTGT
TCGCGAGTCCGCGTGGCCGACCGCGGCCTGCGGGAAGGCATCCTCCTCTCCCTGATGTCCGAACGCGGGGGCCGCCGCCG
CCGCAGGCGCCGCCGCGGCGGCCGGAGCCCGTCATGA

Upstream 100 bases:

>100_bases
CGTTCAAAGGCTGCGCTTCCGACGCCGTCAAGCGCTTGCTACAGTCGCCGCGAAATGAGGCGGCTCCCCTGGGTCGGCCT
GCGAAGGACGGAAGCAGTCC

Downstream 100 bases:

>100_bases
CCGAACCGCCCCGCAAGCGCATGGTGAAGCCGCCGACCGGCGGGCAGGAGGGCGGCCGCGGCAAGCCCGCGCGCCTGAAG
ACCGCCAAGCAGCGCACCCC

Product: exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNEAPRAPGARDGRDRMRSAGEPPCYAALDLGTNNCRLLIATPSPTGFRVVEAYSRIVRLGEGLTQSGRLSEAAMERALA
ALKVSAEKVRRRRVVRFRAIATQACRIAENGPAFVEQVANETGVRLQIIPPQEEARLSVTGCLNLLDRAMEAALVVDVGG
GSTELSWVDLKEAPPEGMPPIRAWLSVPIGVVTLAERFPEGEAATEGWFRAMVETVKTEIAAFRRADPLKPVFEADRAHL
VGTSGAITSLAGMHLELPRYDRSRVDGIWMSRDECDAAAGRLLALNARERADQPCIGPDRADLVLAGAAILQAVQELWPC
SRVRVADRGLREGILLSLMSERGGRRRRRRRRGGRSPS

Sequences:

>Translated_358_residues
MNEAPRAPGARDGRDRMRSAGEPPCYAALDLGTNNCRLLIATPSPTGFRVVEAYSRIVRLGEGLTQSGRLSEAAMERALA
ALKVSAEKVRRRRVVRFRAIATQACRIAENGPAFVEQVANETGVRLQIIPPQEEARLSVTGCLNLLDRAMEAALVVDVGG
GSTELSWVDLKEAPPEGMPPIRAWLSVPIGVVTLAERFPEGEAATEGWFRAMVETVKTEIAAFRRADPLKPVFEADRAHL
VGTSGAITSLAGMHLELPRYDRSRVDGIWMSRDECDAAAGRLLALNARERADQPCIGPDRADLVLAGAAILQAVQELWPC
SRVRVADRGLREGILLSLMSERGGRRRRRRRRGGRSPS
>Mature_358_residues
MNEAPRAPGARDGRDRMRSAGEPPCYAALDLGTNNCRLLIATPSPTGFRVVEAYSRIVRLGEGLTQSGRLSEAAMERALA
ALKVSAEKVRRRRVVRFRAIATQACRIAENGPAFVEQVANETGVRLQIIPPQEEARLSVTGCLNLLDRAMEAALVVDVGG
GSTELSWVDLKEAPPEGMPPIRAWLSVPIGVVTLAERFPEGEAATEGWFRAMVETVKTEIAAFRRADPLKPVFEADRAHL
VGTSGAITSLAGMHLELPRYDRSRVDGIWMSRDECDAAAGRLLALNARERADQPCIGPDRADLVLAGAAILQAVQELWPC
SRVRVADRGLREGILLSLMSERGGRRRRRRRRGGRSPS

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=333, Percent_Identity=27.9279279279279, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788848, Length=332, Percent_Identity=27.4096385542169, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39029; Mature: 39029

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEAPRAPGARDGRDRMRSAGEPPCYAALDLGTNNCRLLIATPSPTGFRVVEAYSRIVRL
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHH
GEGLTQSGRLSEAAMERALAALKVSAEKVRRRRVVRFRAIATQACRIAENGPAFVEQVAN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ETGVRLQIIPPQEEARLSVTGCLNLLDRAMEAALVVDVGGGSTELSWVDLKEAPPEGMPP
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCCCCCH
IRAWLSVPIGVVTLAERFPEGEAATEGWFRAMVETVKTEIAAFRRADPLKPVFEADRAHL
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEE
VGTSGAITSLAGMHLELPRYDRSRVDGIWMSRDECDAAAGRLLALNARERADQPCIGPDR
EECCCHHHHHHCCEEECCCCCCHHCCCEECCCHHHHHHCCCEEEEECHHHCCCCCCCCCC
ADLVLAGAAILQAVQELWPCSRVRVADRGLREGILLSLMSERGGRRRRRRRRGGRSPS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNEAPRAPGARDGRDRMRSAGEPPCYAALDLGTNNCRLLIATPSPTGFRVVEAYSRIVRL
CCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHH
GEGLTQSGRLSEAAMERALAALKVSAEKVRRRRVVRFRAIATQACRIAENGPAFVEQVAN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ETGVRLQIIPPQEEARLSVTGCLNLLDRAMEAALVVDVGGGSTELSWVDLKEAPPEGMPP
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCCCCCH
IRAWLSVPIGVVTLAERFPEGEAATEGWFRAMVETVKTEIAAFRRADPLKPVFEADRAHL
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEE
VGTSGAITSLAGMHLELPRYDRSRVDGIWMSRDECDAAAGRLLALNARERADQPCIGPDR
EECCCHHHHHHCCEEECCCCCCHHCCCEECCCHHHHHHCCCEEEEECHHHCCCCCCCCCC
ADLVLAGAAILQAVQELWPCSRVRVADRGLREGILLSLMSERGGRRRRRRRRGGRSPS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]