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The map label for this gene is yhdH [H]

Identifier: 197104860

GI number: 197104860

Start: 1575964

End: 1577346

Strand: Direct

Name: yhdH [H]

Synonym: PHZ_c1394

Alternate gene names: 197104860

Gene position: 1575964-1577346 (Clockwise)

Preceding gene: 197104859

Following gene: 197104862

Centisome position: 39.44

GC content: 73.9

Gene sequence:

>1383_bases
ATGACGATCGCAGACTCCGCCGCCTCGGGCGCGCGGACGCAAACCGGTGCGGCCGACGCCGCGCCCGAGTGGTCCTCGCG
GGCCGCCTTCATCGCCGCGGCGGTGGGCTCGGCCGTGGGCCTCGGGAACATCTGGAAGTTCCCCTACATGGCCGGGGTCA
GCGGCGGCGGGGCCTTCGTGCTGACCTACCTCGGATTCGTGGCCCTCGTCGGCGTCCCGGTGCTGATCGCCGAGCTGCTG
CTCGGCCGGCATGGCGGGCCCAGCATCGTGCAGGCCCTCGGTCGGATGGCGGCCGGCGCCCGGGGAGGGCGGCTGTGGAA
CGGCCTGGGCTGGTTCGTCGCGCTGACGGCCCTGGGCGTCCTCAGCTTCTACAGCGTGGTCGCGGGTTGGGCGCTCGCCT
ATGCGGCCAAGGCGGCGGTGGGCGGGCTCTCGGCCCTGACGCCCCAGGCCAGCACCCGGACGTTCGACGCCCTGCTCGCC
GACCCGGCCCAGATGATCGCCTGGCACACCCTGGTGATGGGCGCCGTCGTCGCCATCGTTGCGCGCGGCGTGAAGGGCGG
CATCGAGCGGGCCGTGCGCTGGCTGATGCCGCTCCTGACGGCGCTGCTGGTCGTGCTGGCGGTCTACGCCGGCGGGGTGG
GGGATTTCGCCCGCGCCGTGGAGTTCCTGTTCCGGCCCGACGTCTCGGCGCTCACCCCGGAGGTCGCCATGGCGGCGGCG
GGGCACGCGTTCTTCACCCTGTCGCTGGGGCTGGGGGCGATGATGGTCTACGGCGCCTATGTACCGAAGTCGGTCTCGAT
ACCCCGGGCGGCGGTCTGGGTGGCGGCGGCCGACACCGTCTGCGCCCTGCTGGCGGGGCTGGCGATCTTCCCGCTGGTGT
TCGGCTTCGGCCTCGATCCGGCGGCGGGGCCGGGCCTGATCTTCGTGACCCTGCCGGTGGCGTTCGCGGCCATGCCCGGC
GGCGCGGTGGTCGGGGCGCTCTTCTTCCTGCTGATCGTCGTGGCGGCGCTGACGTCAGCGGTGGCGCTGATCGAGCCTCT
GGCCGCCGCCCTGGGCGGCGCGGGCGAGCGTCGGCGGGTCTGGACCCTGCGCCTGGCCGCCGGAGCGTGGGCGCTGGGCC
TGGCCTCGGTGTTCTCGTTCAACCTGTGGTCGGACGTGCGGCTCTTCGGCCAGACGGTGTTCGACTTCATCGCCCATGTG
ACCGGCGACCTGGCGTTGCCCCTGGGCGGGCTGGGCTTCGCCGTCTTCGCCGGCTGGGTCGCCGGCCGTTCGCTCACCGC
GGCCGACTTCGGCTCGCCGCGCGTGCACGCGGCCTGGCTGCTGCTGGTCCGCTTCGTCGCGCCCACCGTGCTGGCGCTGG
TGTTCCTGGACCTGCTGGTCTGA

Upstream 100 bases:

>100_bases
CGACATGAGCTTCAACATGGGCGGCGTGCCGTTCCCCGGCCTCCGGATGACCAAGCCTCTCCGAGCGGCTGAACGCCTCA
CTCTCTGAAGGTTGACGACA

Downstream 100 bases:

>100_bases
GCCCCTAGTTCGCGTTCGCCTCGGCGATCGCCTCGGGCGTCGGACAGACATCGCCGATCCGGCGGGCCTCGGTGGAGGCC
CGTCCGGAGATGTCCAGGCC

Product: sodium-dependent transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTIADSAASGARTQTGAADAAPEWSSRAAFIAAAVGSAVGLGNIWKFPYMAGVSGGGAFVLTYLGFVALVGVPVLIAELL
LGRHGGPSIVQALGRMAAGARGGRLWNGLGWFVALTALGVLSFYSVVAGWALAYAAKAAVGGLSALTPQASTRTFDALLA
DPAQMIAWHTLVMGAVVAIVARGVKGGIERAVRWLMPLLTALLVVLAVYAGGVGDFARAVEFLFRPDVSALTPEVAMAAA
GHAFFTLSLGLGAMMVYGAYVPKSVSIPRAAVWVAAADTVCALLAGLAIFPLVFGFGLDPAAGPGLIFVTLPVAFAAMPG
GAVVGALFFLLIVVAALTSAVALIEPLAAALGGAGERRRVWTLRLAAGAWALGLASVFSFNLWSDVRLFGQTVFDFIAHV
TGDLALPLGGLGFAVFAGWVAGRSLTAADFGSPRVHAAWLLLVRFVAPTVLALVFLDLLV

Sequences:

>Translated_460_residues
MTIADSAASGARTQTGAADAAPEWSSRAAFIAAAVGSAVGLGNIWKFPYMAGVSGGGAFVLTYLGFVALVGVPVLIAELL
LGRHGGPSIVQALGRMAAGARGGRLWNGLGWFVALTALGVLSFYSVVAGWALAYAAKAAVGGLSALTPQASTRTFDALLA
DPAQMIAWHTLVMGAVVAIVARGVKGGIERAVRWLMPLLTALLVVLAVYAGGVGDFARAVEFLFRPDVSALTPEVAMAAA
GHAFFTLSLGLGAMMVYGAYVPKSVSIPRAAVWVAAADTVCALLAGLAIFPLVFGFGLDPAAGPGLIFVTLPVAFAAMPG
GAVVGALFFLLIVVAALTSAVALIEPLAAALGGAGERRRVWTLRLAAGAWALGLASVFSFNLWSDVRLFGQTVFDFIAHV
TGDLALPLGGLGFAVFAGWVAGRSLTAADFGSPRVHAAWLLLVRFVAPTVLALVFLDLLV
>Mature_459_residues
TIADSAASGARTQTGAADAAPEWSSRAAFIAAAVGSAVGLGNIWKFPYMAGVSGGGAFVLTYLGFVALVGVPVLIAELLL
GRHGGPSIVQALGRMAAGARGGRLWNGLGWFVALTALGVLSFYSVVAGWALAYAAKAAVGGLSALTPQASTRTFDALLAD
PAQMIAWHTLVMGAVVAIVARGVKGGIERAVRWLMPLLTALLVVLAVYAGGVGDFARAVEFLFRPDVSALTPEVAMAAAG
HAFFTLSLGLGAMMVYGAYVPKSVSIPRAAVWVAAADTVCALLAGLAIFPLVFGFGLDPAAGPGLIFVTLPVAFAAMPGG
AVVGALFFLLIVVAALTSAVALIEPLAAALGGAGERRRVWTLRLAAGAWALGLASVFSFNLWSDVRLFGQTVFDFIAHVT
GDLALPLGGLGFAVFAGWVAGRSLTAADFGSPRVHAAWLLLVRFVAPTVLALVFLDLLV

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=424, Percent_Identity=25, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI21361581, Length=389, Percent_Identity=23.3933161953728, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7657587, Length=408, Percent_Identity=23.7745098039216, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4507043, Length=390, Percent_Identity=23.5897435897436, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI194018524, Length=313, Percent_Identity=25.5591054313099, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4507041, Length=527, Percent_Identity=22.9601518026565, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI171184408, Length=426, Percent_Identity=23.4741784037559, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI171184406, Length=426, Percent_Identity=23.4741784037559, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI171184404, Length=426, Percent_Identity=23.4741784037559, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI92859670, Length=536, Percent_Identity=24.0671641791045, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI33354281, Length=331, Percent_Identity=25.0755287009063, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI197276623, Length=373, Percent_Identity=25.4691689008043, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI54607094, Length=373, Percent_Identity=25.4691689008043, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI58219014, Length=318, Percent_Identity=27.0440251572327, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI289191351, Length=424, Percent_Identity=23.5849056603774, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4557046, Length=424, Percent_Identity=23.5849056603774, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI289191377, Length=424, Percent_Identity=23.5849056603774, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI51468073, Length=322, Percent_Identity=21.7391304347826, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI21361693, Length=142, Percent_Identity=30.2816901408451, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI5032097, Length=359, Percent_Identity=27.0194986072423, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI12408638, Length=289, Percent_Identity=24.5674740484429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI134304856, Length=356, Percent_Identity=25, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI11181770, Length=321, Percent_Identity=23.0529595015576, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI218563756, Length=359, Percent_Identity=26.4623955431755, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI6005715, Length=197, Percent_Identity=25.3807106598985, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI197276625, Length=132, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554804, Length=396, Percent_Identity=25.2525252525253, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=436, Percent_Identity=23.1651376146789, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI133952791, Length=425, Percent_Identity=24.2352941176471, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=122, Percent_Identity=40.1639344262295, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17542050, Length=144, Percent_Identity=31.9444444444444, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17136952, Length=382, Percent_Identity=25.130890052356, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281364394, Length=370, Percent_Identity=25.6756756756757, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28574704, Length=370, Percent_Identity=25.6756756756757, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17136950, Length=370, Percent_Identity=25.6756756756757, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28574702, Length=370, Percent_Identity=25.6756756756757, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24762620, Length=393, Percent_Identity=26.2086513994911, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550877, Length=443, Percent_Identity=23.2505643340858, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45551183, Length=443, Percent_Identity=23.2505643340858, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24661428, Length=401, Percent_Identity=27.431421446384, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221329674, Length=398, Percent_Identity=23.1155778894472, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24639514, Length=398, Percent_Identity=23.1155778894472, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19921936, Length=411, Percent_Identity=26.5206812652068, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652942, Length=384, Percent_Identity=23.9583333333333, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45551088, Length=384, Percent_Identity=23.9583333333333, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24639516, Length=307, Percent_Identity=23.7785016286645, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24655079, Length=327, Percent_Identity=25.3822629969419, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363702, Length=494, Percent_Identity=22.0647773279352, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364136, Length=398, Percent_Identity=25.6281407035176, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24654186, Length=134, Percent_Identity=29.1044776119403, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363700, Length=346, Percent_Identity=23.4104046242775, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582567, Length=361, Percent_Identity=23.2686980609418, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639853, Length=541, Percent_Identity=22.181146025878, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 46904; Mature: 46773

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIADSAASGARTQTGAADAAPEWSSRAAFIAAAVGSAVGLGNIWKFPYMAGVSGGGAFV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCHHHCCCCCHHHH
LTYLGFVALVGVPVLIAELLLGRHGGPSIVQALGRMAAGARGGRLWNGLGWFVALTALGV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LSFYSVVAGWALAYAAKAAVGGLSALTPQASTRTFDALLADPAQMIAWHTLVMGAVVAIV
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
ARGVKGGIERAVRWLMPLLTALLVVLAVYAGGVGDFARAVEFLFRPDVSALTPEVAMAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCHHHHHHHC
GHAFFTLSLGLGAMMVYGAYVPKSVSIPRAAVWVAAADTVCALLAGLAIFPLVFGFGLDP
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAGPGLIFVTLPVAFAAMPGGAVVGALFFLLIVVAALTSAVALIEPLAAALGGAGERRRV
CCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
WTLRLAAGAWALGLASVFSFNLWSDVRLFGQTVFDFIAHVTGDLALPLGGLGFAVFAGWV
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHH
AGRSLTAADFGSPRVHAAWLLLVRFVAPTVLALVFLDLLV
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TIADSAASGARTQTGAADAAPEWSSRAAFIAAAVGSAVGLGNIWKFPYMAGVSGGGAFV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCHHHCCCCCHHHH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HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]