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The map label for this gene is pyrC` [H]

Identifier: 197104786

GI number: 197104786

Start: 1499068

End: 1500363

Strand: Reverse

Name: pyrC` [H]

Synonym: PHZ_c1320

Alternate gene names: 197104786

Gene position: 1500363-1499068 (Counterclockwise)

Preceding gene: 197104787

Following gene: 197104785

Centisome position: 37.54

GC content: 71.14

Gene sequence:

>1296_bases
ATGAGCGCCCGCCCCCTCGCCTTCGCCAACGTGCGCCTGCTGGACCCGGCGTCGGGGTTCGACGGTCCGGGCGCGGTGAT
CGTCACCGAGGGCGTGATCGCCGACGTGGTGCCGGGCGGCGACCTGGGCGCGCTTTCGAAGGACATCGAGGTGATCGACG
GGGGCGGCAAGCTGCTGATCCCGGGCCTGATCGACATACGGGTGAAGACCGGCGAGCCGGGCTTCGAGACCAAGGAGACC
CTGAAGTCGGCGGGCCGCGCGGCGGCGGCGGGCGGCGTCACCACCATTGTCGTCCAGCCCGACACCTCGCCGGTGGTGGA
CGAGCCCTCGGTTGTGGACTTCATCCTGCGCCGGGCCCGCGACATCGAGCTGGTCAACGTCTATCCCGCCGGCGCCGCCA
CCAAGGGCGCGATGGGCGAGCGGATGGCCGAAATCGGCCTGATGCACGAGGCCGGCTGCCTCTATGTGACCGACGCCGAC
CGGCCGATCGTAAATTCCAAGGTCTTTCAGCGGGTGCTGAGCTACGCCAAGGCGTTCGACACGCCGGTGGCCCACCGCCC
GGCCGACCCCTGGCTGTCGGCAGGGGCCGCCGCCACCTCGGGCGAGTTCGCCGCGAGGATGGGCCTGCCGAACGTGCCGG
CCATCGCCGAGAAGATCATGCTGGAGCGCGACCTGGCCCTCGCCGAGGTGACGGGCGCCAAGCTGATCGTCGACCAGCTC
ACCACCGCCGCCGCGCTGGAGAGTTTCGAGCGGGCGGTGAAGCGCGGCGTCAACGCCACCGCCACCACCTCGATCAACCA
TCTGTCCTTCAACGAGCTGGACATCGGCGACTACCGCACCTTCTGCAAGCTGGACCCGCCGCTGCGCAGCGAGGACGACC
GCCAGGCGGTGATCGAGGCCGTCGCCTCCGGCCTCATCAAGGTGATCGTCTCGGCCCACGCCCCGGCGCCCGCCGAGGAC
AAGCGCCTGCCCTACGACGAGGCCGCCCCCGGCGCGGTGGGGCTCGAGACCCTGCTGCCCGCCCTGCTCGCCTTCCACCA
CGAGGGCCGCATCCCGCTGATCGACCTGGTCCGCACCGTCACCAGCGCCCCGGCCGAGCTTTTGGGCCTGCCCGGCGGCC
GCATCGCCAAGGGCGCCCCGGCCGACCTCGTGCTGGTCGATCCCGACGCCCCCGTGGTGATCGACGCCGACAAGCTGACC
TCGAAATCCAAGAACTCGCCCTTCGACGGCCGCCGCCTGCAGGGAAAGGTGCTGCGCACCGTGGTGGACGGCCGGACGGT
GTACTCGGTCCTCTGA

Upstream 100 bases:

>100_bases
ACGACCTGGCGGTCAGCCTGATCCAGGACCAGGTCGAGATGGGCGTCGCCGCGCGCATGGCGGTCCTCACCTCGCTGGCG
GCGCGGCTGGACAACGAACG

Downstream 100 bases:

>100_bases
TCGTCATCTCCGGGCTCTCGCAGATCACGTCCGGCCACGTTCTCTTTTTGTTTCCATGGCGGCGCTTGCCGTTCTAGACT
TCGCGCGCCTGGCCGCTAGG

Product: aspartate transcarbamoylase, pyrC' subunit

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSARPLAFANVRLLDPASGFDGPGAVIVTEGVIADVVPGGDLGALSKDIEVIDGGGKLLIPGLIDIRVKTGEPGFETKET
LKSAGRAAAAGGVTTIVVQPDTSPVVDEPSVVDFILRRARDIELVNVYPAGAATKGAMGERMAEIGLMHEAGCLYVTDAD
RPIVNSKVFQRVLSYAKAFDTPVAHRPADPWLSAGAAATSGEFAARMGLPNVPAIAEKIMLERDLALAEVTGAKLIVDQL
TTAAALESFERAVKRGVNATATTSINHLSFNELDIGDYRTFCKLDPPLRSEDDRQAVIEAVASGLIKVIVSAHAPAPAED
KRLPYDEAAPGAVGLETLLPALLAFHHEGRIPLIDLVRTVTSAPAELLGLPGGRIAKGAPADLVLVDPDAPVVIDADKLT
SKSKNSPFDGRRLQGKVLRTVVDGRTVYSVL

Sequences:

>Translated_431_residues
MSARPLAFANVRLLDPASGFDGPGAVIVTEGVIADVVPGGDLGALSKDIEVIDGGGKLLIPGLIDIRVKTGEPGFETKET
LKSAGRAAAAGGVTTIVVQPDTSPVVDEPSVVDFILRRARDIELVNVYPAGAATKGAMGERMAEIGLMHEAGCLYVTDAD
RPIVNSKVFQRVLSYAKAFDTPVAHRPADPWLSAGAAATSGEFAARMGLPNVPAIAEKIMLERDLALAEVTGAKLIVDQL
TTAAALESFERAVKRGVNATATTSINHLSFNELDIGDYRTFCKLDPPLRSEDDRQAVIEAVASGLIKVIVSAHAPAPAED
KRLPYDEAAPGAVGLETLLPALLAFHHEGRIPLIDLVRTVTSAPAELLGLPGGRIAKGAPADLVLVDPDAPVVIDADKLT
SKSKNSPFDGRRLQGKVLRTVVDGRTVYSVL
>Mature_430_residues
SARPLAFANVRLLDPASGFDGPGAVIVTEGVIADVVPGGDLGALSKDIEVIDGGGKLLIPGLIDIRVKTGEPGFETKETL
KSAGRAAAAGGVTTIVVQPDTSPVVDEPSVVDFILRRARDIELVNVYPAGAATKGAMGERMAEIGLMHEAGCLYVTDADR
PIVNSKVFQRVLSYAKAFDTPVAHRPADPWLSAGAAATSGEFAARMGLPNVPAIAEKIMLERDLALAEVTGAKLIVDQLT
TAAALESFERAVKRGVNATATTSINHLSFNELDIGDYRTFCKLDPPLRSEDDRQAVIEAVASGLIKVIVSAHAPAPAEDK
RLPYDEAAPGAVGLETLLPALLAFHHEGRIPLIDLVRTVTSAPAELLGLPGGRIAKGAPADLVLVDPDAPVVIDADKLTS
KSKNSPFDGRRLQGKVLRTVVDGRTVYSVL

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=385, Percent_Identity=26.7532467532467, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786722, Length=429, Percent_Identity=25.4079254079254, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193204318, Length=380, Percent_Identity=25.5263157894737, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=193, Percent_Identity=29.0155440414508, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642586, Length=376, Percent_Identity=27.1276595744681, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859883, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 45156; Mature: 45025

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPLAFANVRLLDPASGFDGPGAVIVTEGVIADVVPGGDLGALSKDIEVIDGGGKLLI
CCCCCEEEEEEEEECCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCEEEECCCEEEE
PGLIDIRVKTGEPGFETKETLKSAGRAAAAGGVTTIVVQPDTSPVVDEPSVVDFILRRAR
CCEEEEEEECCCCCCCHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
DIELVNVYPAGAATKGAMGERMAEIGLMHEAGCLYVTDADRPIVNSKVFQRVLSYAKAFD
CEEEEEEECCCCCCCCHHHHHHHHHCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
TPVAHRPADPWLSAGAAATSGEFAARMGLPNVPAIAEKIMLERDLALAEVTGAKLIVDQL
CCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHH
TTAAALESFERAVKRGVNATATTSINHLSFNELDIGDYRTFCKLDPPLRSEDDRQAVIEA
HHHHHHHHHHHHHHCCCCCEEECEECCCCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHH
VASGLIKVIVSAHAPAPAEDKRLPYDEAAPGAVGLETLLPALLAFHHEGRIPLIDLVRTV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
TSAPAELLGLPGGRIAKGAPADLVLVDPDAPVVIDADKLTSKSKNSPFDGRRLQGKVLRT
HHCCHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHH
VVDGRTVYSVL
HHCCCEEECCC
>Mature Secondary Structure 
SARPLAFANVRLLDPASGFDGPGAVIVTEGVIADVVPGGDLGALSKDIEVIDGGGKLLI
CCCCEEEEEEEEECCCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCEEEECCCEEEE
PGLIDIRVKTGEPGFETKETLKSAGRAAAAGGVTTIVVQPDTSPVVDEPSVVDFILRRAR
CCEEEEEEECCCCCCCHHHHHHHCCCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
DIELVNVYPAGAATKGAMGERMAEIGLMHEAGCLYVTDADRPIVNSKVFQRVLSYAKAFD
CEEEEEEECCCCCCCCHHHHHHHHHCCEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
TPVAHRPADPWLSAGAAATSGEFAARMGLPNVPAIAEKIMLERDLALAEVTGAKLIVDQL
CCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHH
TTAAALESFERAVKRGVNATATTSINHLSFNELDIGDYRTFCKLDPPLRSEDDRQAVIEA
HHHHHHHHHHHHHHCCCCCEEECEECCCCCCCCCCCCCHHEEECCCCCCCCCHHHHHHHH
VASGLIKVIVSAHAPAPAEDKRLPYDEAAPGAVGLETLLPALLAFHHEGRIPLIDLVRTV
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
TSAPAELLGLPGGRIAKGAPADLVLVDPDAPVVIDADKLTSKSKNSPFDGRRLQGKVLRT
HHCCHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEHHHHCCCCCCCCCCCCHHHHHHHHH
VVDGRTVYSVL
HHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA