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The map label for this gene is pbpG [H]

Identifier: 197104581

GI number: 197104581

Start: 1277834

End: 1279660

Strand: Direct

Name: pbpG [H]

Synonym: PHZ_c1115

Alternate gene names: 197104581

Gene position: 1277834-1279660 (Clockwise)

Preceding gene: 197104580

Following gene: 197104582

Centisome position: 31.98

GC content: 73.73

Gene sequence:

>1827_bases
GTGCTCGCCCTAGCCGCCGCCGCCAACCTGGCCCTGGCCCAGGCGCCCGAACTGCCGCGCCTTCCCGAGATCCGCCGCGA
CCCGCAGATCACCTATGTGGACCGCTCGGGCGCCGTGATCGGCGTGCGCGGGGGACGCTACGCTCCGCCCGTGGACCTCG
GGCGGCTTCCGGCCCATGTGCCCGCCGCCTTCGTGGCCATCGAGGACCGCCGCTTCTACGAGCACAACGGCGTCGACGCC
CGCGGCATCGCCCGCGCTCTGGTCGTGGCCGTCGGCGAGGGCAAGGCGACCCAGGGCGCCTCGACCATCACCCAGCAACT
CGCGCGCAACCTGTTCCTGAGCCAGGACCGCACGCTGGAGCGCAAGGCGACCGAGATCGCCTACGCCCTGCAGCTCGAGC
GGACCTATTCGAAGAAGCAGATCCTCGCCCTCTACCTCAGCCGCGTCTACTTCGGCTCGGGCGCCTACGGGCTGGAGGCC
GCCGCCCAGCGCTATTTCAACAAGCCGGCGGCGAAGCTCACCGTCCGCGAGGCGGCGATCCTGGCGGGCGTGCTGAAGTC
CCCCACCAACTACAATCCGGCGCTCGAGACCGAGGCGGCGCTGGCCCGCTCGAAGCTGGTGCTGGACGCCATGGTGGAGA
CCGGGGCGATCTCGCCCGCCACCCGGAAGAAGGCGCTGGCCCAGACGCCGCGCATCTGGAAGACCGCGCCGACCGCGGGC
GCGCAATACTTCATCGACTGGATCGACGGCCAGGTGCGGCAGACGGCGGGCAAGGTCCGCCAGGACGTGATCGTCGAGAC
CACCCTGGACCTTCCCATGGAGATGGCCGCCGCCGACGCCGCCCGCAGGACCGCGGCCGCGCACGCCTCGGCCCGGGCCG
AGCAGGCCGCCGTCGTGGCGATCGACGGACAGGGGCGGGTGCGCGCCCTGGTGGGCGGGACCGACTATGCGCGCGCGCCC
TATAACCGCGCCGCCAGCGCCAAGCGCCAGGCCGGCTCGGCCTGGAAGCCGTTCGTCTACCTGGCCGCCCTGGAGGCGGG
ACTGACGCCGGATGCGCCCGTGGTGGACGAGCCGGTGACCATCGCCGGCTGGAGCCCCGACAACTACACCCTGACCCATC
TTGGCCCCATCACCCTCGAGCAGGCGGCGGCCCAGTCGGTGAACACCGTCGCCGCCCGCCTGGCCGACGAGGTCGGCCGC
CAGAACGTGGCCGCCACGGCCCGGCGGCTCGGCATCGTCTCGGCCGTGAACACCGACCCGGCCATGGCGCTGGGCACCAG
CCTCGTCACGCCTCTGGAGATGACGGCGGCCTACACCGCCTTCGCCAACGGCGGGATGCGGGTGCAGCCCTACGGGATCG
AGCGCATCCGGACCCGCAGCGGCGTGACGCTCTACCAGCGCAAGCCCCAGCCTCCGGTCGCGGCCGTGGCGAACCCGCCG
CTGAGCGACCTGAACCGGATGCTGCGCACGGCGATCGCCTCGGGCACCGGCGCGCGGGCGAAGGTCCCGGGCTACGACCT
AGCCGGAAAGACGGGGACCACCTCCGACTACCGCGACGCCTGGTTCTGCGGCTACACGGGCGGGCTCGCCGCCTGCGCCT
GGATGGGCCGGGACGACAATACGCCCATGGGCCGGATCACCGGCGGCGGCGCGCCGGCCGAGCTGTGGCGCGGCTTCATG
GCGACGGCGCTGAGGCGGGTCCCGGCGCAGGCGATCCCGGCCGGGCCGCCCGTCGCTCCGCCGCCCCCGCCGCCGGTGGA
AGCCGAACCGGTCCTGACGCCGACGGCGGCCGAGACGGACTTGCCGCCGGAGCCCGACCCCGGTTAG

Upstream 100 bases:

>100_bases
GGATTACCGCGAATTATCTTGGCCCCCGGCCCGCCGCGCGGGAGAAGGAGCGCGAGAAACCGCCGGGCGCCGGGGGGCGT
CCCGCCTGAGGAGCTGACGC

Downstream 100 bases:

>100_bases
GCCTTGGTCCCTGGAGGGACCGATGCGCACACCGACCTTCGCCGCCGTCCTCGCCGTCCTGACCGGGGCAGCCCTCGCCG
GGGGCGGAGCGGCCCTCGCC

Product: penicillin-binding protein, 1A family

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MLALAAAANLALAQAPELPRLPEIRRDPQITYVDRSGAVIGVRGGRYAPPVDLGRLPAHVPAAFVAIEDRRFYEHNGVDA
RGIARALVVAVGEGKATQGASTITQQLARNLFLSQDRTLERKATEIAYALQLERTYSKKQILALYLSRVYFGSGAYGLEA
AAQRYFNKPAAKLTVREAAILAGVLKSPTNYNPALETEAALARSKLVLDAMVETGAISPATRKKALAQTPRIWKTAPTAG
AQYFIDWIDGQVRQTAGKVRQDVIVETTLDLPMEMAAADAARRTAAAHASARAEQAAVVAIDGQGRVRALVGGTDYARAP
YNRAASAKRQAGSAWKPFVYLAALEAGLTPDAPVVDEPVTIAGWSPDNYTLTHLGPITLEQAAAQSVNTVAARLADEVGR
QNVAATARRLGIVSAVNTDPAMALGTSLVTPLEMTAAYTAFANGGMRVQPYGIERIRTRSGVTLYQRKPQPPVAAVANPP
LSDLNRMLRTAIASGTGARAKVPGYDLAGKTGTTSDYRDAWFCGYTGGLAACAWMGRDDNTPMGRITGGGAPAELWRGFM
ATALRRVPAQAIPAGPPVAPPPPPPVEAEPVLTPTAAETDLPPEPDPG

Sequences:

>Translated_608_residues
MLALAAAANLALAQAPELPRLPEIRRDPQITYVDRSGAVIGVRGGRYAPPVDLGRLPAHVPAAFVAIEDRRFYEHNGVDA
RGIARALVVAVGEGKATQGASTITQQLARNLFLSQDRTLERKATEIAYALQLERTYSKKQILALYLSRVYFGSGAYGLEA
AAQRYFNKPAAKLTVREAAILAGVLKSPTNYNPALETEAALARSKLVLDAMVETGAISPATRKKALAQTPRIWKTAPTAG
AQYFIDWIDGQVRQTAGKVRQDVIVETTLDLPMEMAAADAARRTAAAHASARAEQAAVVAIDGQGRVRALVGGTDYARAP
YNRAASAKRQAGSAWKPFVYLAALEAGLTPDAPVVDEPVTIAGWSPDNYTLTHLGPITLEQAAAQSVNTVAARLADEVGR
QNVAATARRLGIVSAVNTDPAMALGTSLVTPLEMTAAYTAFANGGMRVQPYGIERIRTRSGVTLYQRKPQPPVAAVANPP
LSDLNRMLRTAIASGTGARAKVPGYDLAGKTGTTSDYRDAWFCGYTGGLAACAWMGRDDNTPMGRITGGGAPAELWRGFM
ATALRRVPAQAIPAGPPVAPPPPPPVEAEPVLTPTAAETDLPPEPDPG
>Mature_608_residues
MLALAAAANLALAQAPELPRLPEIRRDPQITYVDRSGAVIGVRGGRYAPPVDLGRLPAHVPAAFVAIEDRRFYEHNGVDA
RGIARALVVAVGEGKATQGASTITQQLARNLFLSQDRTLERKATEIAYALQLERTYSKKQILALYLSRVYFGSGAYGLEA
AAQRYFNKPAAKLTVREAAILAGVLKSPTNYNPALETEAALARSKLVLDAMVETGAISPATRKKALAQTPRIWKTAPTAG
AQYFIDWIDGQVRQTAGKVRQDVIVETTLDLPMEMAAADAARRTAAAHASARAEQAAVVAIDGQGRVRALVGGTDYARAP
YNRAASAKRQAGSAWKPFVYLAALEAGLTPDAPVVDEPVTIAGWSPDNYTLTHLGPITLEQAAAQSVNTVAARLADEVGR
QNVAATARRLGIVSAVNTDPAMALGTSLVTPLEMTAAYTAFANGGMRVQPYGIERIRTRSGVTLYQRKPQPPVAAVANPP
LSDLNRMLRTAIASGTGARAKVPGYDLAGKTGTTSDYRDAWFCGYTGGLAACAWMGRDDNTPMGRITGGGAPAELWRGFM
ATALRRVPAQAIPAGPPVAPPPPPPVEAEPVLTPTAAETDLPPEPDPG

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=548, Percent_Identity=32.8467153284672, Blast_Score=225, Evalue=8e-60,
Organism=Escherichia coli, GI87082258, Length=231, Percent_Identity=42.8571428571429, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1788867, Length=516, Percent_Identity=30.6201550387597, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1789601, Length=169, Percent_Identity=40.2366863905325, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 64246; Mature: 64246

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALAAAANLALAQAPELPRLPEIRRDPQITYVDRSGAVIGVRGGRYAPPVDLGRLPAHV
CEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCC
PAAFVAIEDRRFYEHNGVDARGIARALVVAVGEGKATQGASTITQQLARNLFLSQDRTLE
CEEEEEEECCHHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHH
RKATEIAYALQLERTYSKKQILALYLSRVYFGSGAYGLEAAAQRYFNKPAAKLTVREAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
LAGVLKSPTNYNPALETEAALARSKLVLDAMVETGAISPATRKKALAQTPRIWKTAPTAG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCCC
AQYFIDWIDGQVRQTAGKVRQDVIVETTLDLPMEMAAADAARRTAAAHASARAEQAAVVA
HHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
IDGQGRVRALVGGTDYARAPYNRAASAKRQAGSAWKPFVYLAALEAGLTPDAPVVDEPVT
ECCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHEEHHHHHCCCCCCCCCCCCEE
IAGWSPDNYTLTHLGPITLEQAAAQSVNTVAARLADEVGRQNVAATARRLGIVSAVNTDP
EECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
AMALGTSLVTPLEMTAAYTAFANGGMRVQPYGIERIRTRSGVTLYQRKPQPPVAAVANPP
HHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCEEEECCCCCCEEECCCCC
LSDLNRMLRTAIASGTGARAKVPGYDLAGKTGTTSDYRDAWFCGYTGGLAACAWMGRDDN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCCC
TPMGRITGGGAPAELWRGFMATALRRVPAQAIPAGPPVAPPPPPPVEAEPVLTPTAAETD
CCCCEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPPEPDPG
CCCCCCCC
>Mature Secondary Structure
MLALAAAANLALAQAPELPRLPEIRRDPQITYVDRSGAVIGVRGGRYAPPVDLGRLPAHV
CEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCC
PAAFVAIEDRRFYEHNGVDARGIARALVVAVGEGKATQGASTITQQLARNLFLSQDRTLE
CEEEEEEECCHHHHCCCCCHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHH
RKATEIAYALQLERTYSKKQILALYLSRVYFGSGAYGLEAAAQRYFNKPAAKLTVREAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
LAGVLKSPTNYNPALETEAALARSKLVLDAMVETGAISPATRKKALAQTPRIWKTAPTAG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCCCC
AQYFIDWIDGQVRQTAGKVRQDVIVETTLDLPMEMAAADAARRTAAAHASARAEQAAVVA
HHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
IDGQGRVRALVGGTDYARAPYNRAASAKRQAGSAWKPFVYLAALEAGLTPDAPVVDEPVT
ECCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHEEHHHHHCCCCCCCCCCCCEE
IAGWSPDNYTLTHLGPITLEQAAAQSVNTVAARLADEVGRQNVAATARRLGIVSAVNTDP
EECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
AMALGTSLVTPLEMTAAYTAFANGGMRVQPYGIERIRTRSGVTLYQRKPQPPVAAVANPP
HHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCEEEECCCCCCEEECCCCC
LSDLNRMLRTAIASGTGARAKVPGYDLAGKTGTTSDYRDAWFCGYTGGLAACAWMGRDDN
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCCC
TPMGRITGGGAPAELWRGFMATALRRVPAQAIPAGPPVAPPPPPPVEAEPVLTPTAAETD
CCCCEEECCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPPEPDPG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]