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The map label for this gene is degP [H]

Identifier: 197104553

GI number: 197104553

Start: 1229534

End: 1230646

Strand: Direct

Name: degP [H]

Synonym: PHZ_c1087

Alternate gene names: 197104553

Gene position: 1229534-1230646 (Clockwise)

Preceding gene: 197104552

Following gene: 197104555

Centisome position: 30.77

GC content: 76.19

Gene sequence:

>1113_bases
ATGAGGAGAGCTGACGCGAGCGTGCTGGCGGCCGTCCTGGCGCCCGCCCTGATCCTGGGGCTCGCCGGCTGCGAGCAGCG
GCAGGCCGAGCCGCCGGCCGAGCAGAGCACGGCGGTGCAGCCGCCGGTGATCGCCACCCCGGCCGGCGGAGCGCCCAGTT
CCTTCGCCCCGATCGTCAAGCGGGTCTCGCCGGCGGTCGTGTCGATCGACACCTTGGCGGTGGCCGAGGGCGCGCTGCCC
TGGCTGCAGGGGACGCCGCAGGGCGGGCTGCCCGGCTTCGCGGTCCCGGTGCAGCGCGGGGCCGGCTCGGGCTTCATCAT
CAGCGCCGACGGCTACATCGTCACCAACAACCACGTGGTGGAGGGCGCGCAGGAGATCGTCGCGACCCTGGCGGACGGCC
GCCAGCTTCCGGCGCGGCTGGTGGGGCGCGACCCGCCCTCGGACCTGGCGGTGCTGAAGGTGGACGCCCGCGAGCTGCCG
TTCGTCAGCTTCGCGCGCTCGGCCCTGCCGGAGGTGGGCGACTGGGTGGTGGCGGTCGGCAACCCCTTCGGCCTGGGCGG
CACGGCGACGGCCGGGATCGTCTCGGCGCACGGCCGCGAGATCGGCGAGGCCTACGTCAGCTACCTGCAGATCGACGCGC
CCATCAACAGCGGCAACTCGGGCGGGCCGTCCTTCGACCTGCAGGGCCGGGTGGTGGGGGTGAACACCGCGATCTTCTCG
CCCAGCGGCGGCTCGGTCGGCATCGGCTTCGCGATCCCCGCGGACCTGGCCGAGAACGTCACCCAGCAGCTCATCAAGTC
CGGCCGGGTGACCCGCGGCTACCTCGGCGTGGGGGTCCAGGACCTGACCCCGCCGCTGGCGGCTCGGCTGGGCGCGCGCG
GCGCGCGCGGCGGGCTGATCGTCGACGTGGCGCGCGGCGGTCCTGCCGCGGGTGCGCTGCGGCCCGGCGACGTGGTGACG
GCGGTGAACGGGGAGGAGATCACCGGCGCCGGCGGGTTGACCCGGGCCATCGCCGCGGCGGCGCCCGGCAGCCGGCTGCG
GCTGCAGGTCCTGCGCGGCGGCCGGCGCTCGGAGGTGACGGTCACGGCGGCGCGCCGGCCGGACGACCTGTAG

Upstream 100 bases:

>100_bases
GAACGGGCGGGCGTTCCGACTTGCCCGCGGCCGGGCGCTCCTGTGTAACCGGCCGGCGGGCCGGGCGTTGGAGCGGGGAC
CTTCGACATATGAGGTGGAG

Downstream 100 bases:

>100_bases
AAGGCCGGTCCCGAGCCGAGCATTTCGGGCCAGCCCCTCCACCATGCTGCGCATGGTCCCCCTCCCCCGGCGGGGGAGGA
GGAGGTCAGCGGACGGCGTT

Product: serine protease HtrA

Products: NA

Alternate protein names: Antigen htrA [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRRADASVLAAVLAPALILGLAGCEQRQAEPPAEQSTAVQPPVIATPAGGAPSSFAPIVKRVSPAVVSIDTLAVAEGALP
WLQGTPQGGLPGFAVPVQRGAGSGFIISADGYIVTNNHVVEGAQEIVATLADGRQLPARLVGRDPPSDLAVLKVDARELP
FVSFARSALPEVGDWVVAVGNPFGLGGTATAGIVSAHGREIGEAYVSYLQIDAPINSGNSGGPSFDLQGRVVGVNTAIFS
PSGGSVGIGFAIPADLAENVTQQLIKSGRVTRGYLGVGVQDLTPPLAARLGARGARGGLIVDVARGGPAAGALRPGDVVT
AVNGEEITGAGGLTRAIAAAAPGSRLRLQVLRGGRRSEVTVTAARRPDDL

Sequences:

>Translated_370_residues
MRRADASVLAAVLAPALILGLAGCEQRQAEPPAEQSTAVQPPVIATPAGGAPSSFAPIVKRVSPAVVSIDTLAVAEGALP
WLQGTPQGGLPGFAVPVQRGAGSGFIISADGYIVTNNHVVEGAQEIVATLADGRQLPARLVGRDPPSDLAVLKVDARELP
FVSFARSALPEVGDWVVAVGNPFGLGGTATAGIVSAHGREIGEAYVSYLQIDAPINSGNSGGPSFDLQGRVVGVNTAIFS
PSGGSVGIGFAIPADLAENVTQQLIKSGRVTRGYLGVGVQDLTPPLAARLGARGARGGLIVDVARGGPAAGALRPGDVVT
AVNGEEITGAGGLTRAIAAAAPGSRLRLQVLRGGRRSEVTVTAARRPDDL
>Mature_370_residues
MRRADASVLAAVLAPALILGLAGCEQRQAEPPAEQSTAVQPPVIATPAGGAPSSFAPIVKRVSPAVVSIDTLAVAEGALP
WLQGTPQGGLPGFAVPVQRGAGSGFIISADGYIVTNNHVVEGAQEIVATLADGRQLPARLVGRDPPSDLAVLKVDARELP
FVSFARSALPEVGDWVVAVGNPFGLGGTATAGIVSAHGREIGEAYVSYLQIDAPINSGNSGGPSFDLQGRVVGVNTAIFS
PSGGSVGIGFAIPADLAENVTQQLIKSGRVTRGYLGVGVQDLTPPLAARLGARGARGGLIVDVARGGPAAGALRPGDVVT
AVNGEEITGAGGLTRAIAAAAPGSRLRLQVLRGGRRSEVTVTAARRPDDL

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=369, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI24308541, Length=325, Percent_Identity=36.9230769230769, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI22129776, Length=324, Percent_Identity=33.641975308642, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI7019477, Length=327, Percent_Identity=35.7798165137615, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1789629, Length=321, Percent_Identity=42.3676012461059, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1786356, Length=348, Percent_Identity=39.367816091954, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789630, Length=325, Percent_Identity=36.6153846153846, Blast_Score=178, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24646839, Length=298, Percent_Identity=34.8993288590604, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 37196; Mature: 37196

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRADASVLAAVLAPALILGLAGCEQRQAEPPAEQSTAVQPPVIATPAGGAPSSFAPIVK
CCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
RVSPAVVSIDTLAVAEGALPWLQGTPQGGLPGFAVPVQRGAGSGFIISADGYIVTNNHVV
HCCCCEEEEHHHHHHCCCCCHHCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCHHH
EGAQEIVATLADGRQLPARLVGRDPPSDLAVLKVDARELPFVSFARSALPEVGDWVVAVG
HHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEC
NPFGLGGTATAGIVSAHGREIGEAYVSYLQIDAPINSGNSGGPSFDLQGRVVGVNTAIFS
CCCCCCCCHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCCCEEECEEEEEEEEEEEC
PSGGSVGIGFAIPADLAENVTQQLIKSGRVTRGYLGVGVQDLTPPLAARLGARGARGGLI
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCHHHHHHCCCCCCCCEE
VDVARGGPAAGALRPGDVVTAVNGEEITGAGGLTRAIAAAAPGSRLRLQVLRGGRRSEVT
EEECCCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCEEE
VTAARRPDDL
EEECCCCCCC
>Mature Secondary Structure
MRRADASVLAAVLAPALILGLAGCEQRQAEPPAEQSTAVQPPVIATPAGGAPSSFAPIVK
CCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
RVSPAVVSIDTLAVAEGALPWLQGTPQGGLPGFAVPVQRGAGSGFIISADGYIVTNNHVV
HCCCCEEEEHHHHHHCCCCCHHCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCHHH
EGAQEIVATLADGRQLPARLVGRDPPSDLAVLKVDARELPFVSFARSALPEVGDWVVAVG
HHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEC
NPFGLGGTATAGIVSAHGREIGEAYVSYLQIDAPINSGNSGGPSFDLQGRVVGVNTAIFS
CCCCCCCCHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCCCEEECEEEEEEEEEEEC
PSGGSVGIGFAIPADLAENVTQQLIKSGRVTRGYLGVGVQDLTPPLAARLGARGARGGLI
CCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCHHHHHHCCCCCCCCEE
VDVARGGPAAGALRPGDVVTAVNGEEITGAGGLTRAIAAAAPGSRLRLQVLRGGRRSEVT
EEECCCCCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCEEE
VTAARRPDDL
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8027347 [H]