Click here to switch to the map view.

The map label for this gene is dmpD [H]

Identifier: 197104542

GI number: 197104542

Start: 1214070

End: 1215650

Strand: Direct

Name: dmpD [H]

Synonym: PHZ_c1076

Alternate gene names: 197104542

Gene position: 1214070-1215650 (Clockwise)

Preceding gene: 197104540

Following gene: 197104543

Centisome position: 30.38

GC content: 75.14

Gene sequence:

>1581_bases
ATGGGCGAGGCCGCCAAACCCTTCGAGCTCCAGCTCCTCGGCCCGCTCACGGTCCGGCGGGACGGCGCGGCCGAACTGCT
GCCGGCCTCGCGCAAGACCCGCGCCCTGCTGGCCTATCTGACGATCTCCGGGAAGCCCGAGCGGCGCGAGCGCCTGTGCG
AGCTGTTCTGGGACGTGCCGGACGATCCGCGCGGCGCGCTGCGCTGGAGCCTGAGCAAGCTGCGGCCGGTCGTCGACAGC
GGCGACGAGGTGCGGTTGCTGGCCGATCGCGAGTGGGTCGAGATCCGGCTCCCCGACGAGGCCGTCGACTGGCGGCGCCT
GAAGTCCCTCGCCCAGCGGGGCGTCGCCCGGGCGCCGACCGAGGCGCTGCAGGCGGCGGCGGGGGGCGGCGAGCTGCTGG
AGGGCCTGGAGCTTCCGCGCTGCGAGCGCTTCCGCGCCTGGAGCGTGGCGCACCGAGAGGACGTCGTGCGCTGGCGGGGG
CAGGTGCTGCGCGAGCTGACCGGCCGGGCGCTGCCGCCCGAGACGGCGATCGCCCACGCGCGGGCCTGGGTGGAGCTGGA
CGGCGACTCGCCCGAGCCGTGGCGGCGGCTGGTGGGGTTGCTTGAATCCGCGGGCCGGACCCGCGACGCCGACGAGCACC
GGGCGCTGGCCGAGCGTCGCCTGAGGGCGGCCGGCGGCCAGGCGCCCGCCGACCTGCGCGCTCGACCGGCGGCGGTGCGG
GCCGCTGCAGCGCCGCCGGCGGCCGACATCCGCTTCTGCAGCGCCTCGGACGGGGTCTCGATCGCCTACACGGTGCAGGG
CGGCGGGCCGCCGCTGGTGAAGACCGCCAACTGGATGACCCACCTGCAGCGCGACGCCGAGGGGCCCATCTGGCGGCACT
GGATCGCCGAGTTCACGAAGGGGCGCGCCTTCGTCCGCTACGACCAGCGGGGCAACGGCCTCTCGGACTGGAACGCGCCC
TTCAGCGTCGAGGCGTTCGTCGACGACCTGGAGCGGGTGGTGGACGCCGCGGGGCTCGAGCGCTTCGACCTGCTGGGCAT
CTCGCAAGGGGCGGGCGTGGCGGTGGCCTACGCCGTGCGCCATCCCGAACGGGTGCGCCGGATCGTGCTCCTGGGCGGCT
TCGTGAAGGGGTGGGCCCTGCACGCCACGCCCGAGGAGCGCGAGCGGCGCGAGGCCATGCTGACGCTGACGCGGACGGGC
TGGGACCTCGATACGCCGGCCTTCCGGCAGATGTTCACGTCGCTGTTCATCCCCGACGGCGGATCCGACGACCAGCACTG
GTTCAACACCACCCAGAAGCTGTCGACCAACGGCGAGAACGCCTACGCCATCCAGCGCTGCGGGGCCGAGGCGGACGTGG
AGCCCCTGCTGCCCCGCGTCGCCGCGCCGACCCTGGTCGCGCACTGCCGCGGGGACGCGGTCGTGCCGTTCGCCACGGGA
CGCGAGATCGCCAGCCGGATTCCCGGCGCGCGCTTCCTGCCGCTCGAGGGCCGCAACCACATCATCCTGGAGCAGGACGC
CGCGTGGCGGCGGTTCGCGGACGCGGCGCGGGCGTTCCTGGACGAGGCCGACGGCGCCTGA

Upstream 100 bases:

>100_bases
GCCGGCCCGACGGCGTCGCTTCTGACGTCGCGGCGTGGACGCCGCCGTTTGAAAGAACGTTGTAATTGTAGGCGCGCGGG
GGCGGCGCTAGTTTCGACGG

Downstream 100 bases:

>100_bases
CGCGCAGGCTTCCCTTACGTTAACGGTGTTAACTTACGGCGCAGCTCTGGACAGGGCCTGGGAGCGTTCCCAGCTAGGAC
GACGAGCGCCGCCGCGACGG

Product: adenylate/guanylate cyclase/hydrolase, alpha/beta fold family protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MGEAAKPFELQLLGPLTVRRDGAAELLPASRKTRALLAYLTISGKPERRERLCELFWDVPDDPRGALRWSLSKLRPVVDS
GDEVRLLADREWVEIRLPDEAVDWRRLKSLAQRGVARAPTEALQAAAGGGELLEGLELPRCERFRAWSVAHREDVVRWRG
QVLRELTGRALPPETAIAHARAWVELDGDSPEPWRRLVGLLESAGRTRDADEHRALAERRLRAAGGQAPADLRARPAAVR
AAAAPPAADIRFCSASDGVSIAYTVQGGGPPLVKTANWMTHLQRDAEGPIWRHWIAEFTKGRAFVRYDQRGNGLSDWNAP
FSVEAFVDDLERVVDAAGLERFDLLGISQGAGVAVAYAVRHPERVRRIVLLGGFVKGWALHATPEERERREAMLTLTRTG
WDLDTPAFRQMFTSLFIPDGGSDDQHWFNTTQKLSTNGENAYAIQRCGAEADVEPLLPRVAAPTLVAHCRGDAVVPFATG
REIASRIPGARFLPLEGRNHIILEQDAAWRRFADAARAFLDEADGA

Sequences:

>Translated_526_residues
MGEAAKPFELQLLGPLTVRRDGAAELLPASRKTRALLAYLTISGKPERRERLCELFWDVPDDPRGALRWSLSKLRPVVDS
GDEVRLLADREWVEIRLPDEAVDWRRLKSLAQRGVARAPTEALQAAAGGGELLEGLELPRCERFRAWSVAHREDVVRWRG
QVLRELTGRALPPETAIAHARAWVELDGDSPEPWRRLVGLLESAGRTRDADEHRALAERRLRAAGGQAPADLRARPAAVR
AAAAPPAADIRFCSASDGVSIAYTVQGGGPPLVKTANWMTHLQRDAEGPIWRHWIAEFTKGRAFVRYDQRGNGLSDWNAP
FSVEAFVDDLERVVDAAGLERFDLLGISQGAGVAVAYAVRHPERVRRIVLLGGFVKGWALHATPEERERREAMLTLTRTG
WDLDTPAFRQMFTSLFIPDGGSDDQHWFNTTQKLSTNGENAYAIQRCGAEADVEPLLPRVAAPTLVAHCRGDAVVPFATG
REIASRIPGARFLPLEGRNHIILEQDAAWRRFADAARAFLDEADGA
>Mature_525_residues
GEAAKPFELQLLGPLTVRRDGAAELLPASRKTRALLAYLTISGKPERRERLCELFWDVPDDPRGALRWSLSKLRPVVDSG
DEVRLLADREWVEIRLPDEAVDWRRLKSLAQRGVARAPTEALQAAAGGGELLEGLELPRCERFRAWSVAHREDVVRWRGQ
VLRELTGRALPPETAIAHARAWVELDGDSPEPWRRLVGLLESAGRTRDADEHRALAERRLRAAGGQAPADLRARPAAVRA
AAAPPAADIRFCSASDGVSIAYTVQGGGPPLVKTANWMTHLQRDAEGPIWRHWIAEFTKGRAFVRYDQRGNGLSDWNAPF
SVEAFVDDLERVVDAAGLERFDLLGISQGAGVAVAYAVRHPERVRRIVLLGGFVKGWALHATPEERERREAMLTLTRTGW
DLDTPAFRQMFTSLFIPDGGSDDQHWFNTTQKLSTNGENAYAIQRCGAEADVEPLLPRVAAPTLVAHCRGDAVVPFATGR
EIASRIPGARFLPLEGRNHIILEQDAAWRRFADAARAFLDEADGA

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 58198; Mature: 58067

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAAKPFELQLLGPLTVRRDGAAELLPASRKTRALLAYLTISGKPERRERLCELFWDVP
CCCCCCCEEEEEECCEEECCCCCHHHCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHCCC
DDPRGALRWSLSKLRPVVDSGDEVRLLADREWVEIRLPDEAVDWRRLKSLAQRGVARAPT
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCH
EALQAAAGGGELLEGLELPRCERFRAWSVAHREDVVRWRGQVLRELTGRALPPETAIAHA
HHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
RAWVELDGDSPEPWRRLVGLLESAGRTRDADEHRALAERRLRAAGGQAPADLRARPAAVR
EEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AAAAPPAADIRFCSASDGVSIAYTVQGGGPPLVKTANWMTHLQRDAEGPIWRHWIAEFTK
HCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GRAFVRYDQRGNGLSDWNAPFSVEAFVDDLERVVDAAGLERFDLLGISQGAGVAVAYAVR
CCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHH
HPERVRRIVLLGGFVKGWALHATPEERERREAMLTLTRTGWDLDTPAFRQMFTSLFIPDG
CHHHHHEEHHCCCHHHCCEEECCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCC
GSDDQHWFNTTQKLSTNGENAYAIQRCGAEADVEPLLPRVAAPTLVAHCRGDAVVPFATG
CCCCHHHHHHHHHHCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
REIASRIPGARFLPLEGRNHIILEQDAAWRRFADAARAFLDEADGA
HHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GEAAKPFELQLLGPLTVRRDGAAELLPASRKTRALLAYLTISGKPERRERLCELFWDVP
CCCCCCEEEEEECCEEECCCCCHHHCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHCCC
DDPRGALRWSLSKLRPVVDSGDEVRLLADREWVEIRLPDEAVDWRRLKSLAQRGVARAPT
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCH
EALQAAAGGGELLEGLELPRCERFRAWSVAHREDVVRWRGQVLRELTGRALPPETAIAHA
HHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
RAWVELDGDSPEPWRRLVGLLESAGRTRDADEHRALAERRLRAAGGQAPADLRARPAAVR
EEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
AAAAPPAADIRFCSASDGVSIAYTVQGGGPPLVKTANWMTHLQRDAEGPIWRHWIAEFTK
HCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GRAFVRYDQRGNGLSDWNAPFSVEAFVDDLERVVDAAGLERFDLLGISQGAGVAVAYAVR
CCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHH
HPERVRRIVLLGGFVKGWALHATPEERERREAMLTLTRTGWDLDTPAFRQMFTSLFIPDG
CHHHHHEEHHCCCHHHCCEEECCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHCCCCC
GSDDQHWFNTTQKLSTNGENAYAIQRCGAEADVEPLLPRVAAPTLVAHCRGDAVVPFATG
CCCCHHHHHHHHHHCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
REIASRIPGARFLPLEGRNHIILEQDAAWRRFADAARAFLDEADGA
HHHHHHCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]