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The map label for this gene is ptrB [H]

Identifier: 197104537

GI number: 197104537

Start: 1208002

End: 1210125

Strand: Direct

Name: ptrB [H]

Synonym: PHZ_c1071

Alternate gene names: 197104537

Gene position: 1208002-1210125 (Clockwise)

Preceding gene: 197104529

Following gene: 197104539

Centisome position: 30.23

GC content: 69.16

Gene sequence:

>2124_bases
ATGCGCATCGCAACCTTCGCCGCCGCGGCGGCCGTCCTGCTGGCCGGCGCGGCCCAGGCCCAGGCCCAGACTCAGCCCAC
GACGCCGGAGCCGCCGCGGGCGGCCAAGCGCCCCCACGAGGTGAAGGCGCCGGGCGGGACCCGGACGGACGAATACTACT
GGCTGCGCGACGACACCCGGAAGAACCCGGAGATGCTGGCCCACCTGGCCGCCGAGAACGCCTACGCCGACGCGGTGCTG
GCGGCGAACAAGCCGCTGAAGGAAGCGCTCTACAAGGAGATCGTCGGGCGGGTGAAGCAGGACGATGCGTCCGTGCCGTA
CCGCGAGCGGGGCTACTGGTACTACACGCGCTTCGAGGCCGGGAAGGACTACCCGATCCTCGCGCGCCGGAAGGGCGAGA
TGACCGCGCCCGAGGAAATCCTCCTCGAGCAGAACGCAATGGCGCAGGGCAAGGGCTACTTCAACGTCGGCGAGGCGGTG
GTGAGCCAGGACAACCGCCTGCTGGCCTGGGCCGAGGACACGGTGGGCCGGCGCCAGTACGTGCTGAAGGTGAAGGACCT
CGCCACCGGCCAGGTGCTGAGCGACACGGTGGAGAACATCGAGCCCAACATCGTCTGGGCCGACGACAACCGGACGATCT
TCTACATCGAGAAGGACCCGGTGACCCTGCTGTCGAAGCGGGTGAAGGCGCACGTGCTGGGCACGCCGGCCAGCGCCGAC
AGGCTGGTCTACGAGGAGGCGGACGACAGCTTCTACATGGGGCTCGGCCGCACGCGGTCGGACAAGTACCTGTGCGTCCT
GCTGCAGAGCACCACGGCCACCGAGCAGCGCTGCACCCCGGCCGCCGCGCCCGGCGCGCTGCAGGTGGTGGCGCCGCGCG
AGCGGGACCACCTCTACCAGGCCGACCACCTGGCCGGGCGCTGGGTGATCCGCACGAACTGGGACGCGCCGAACTACCGG
CTGATGCAGGCGCCCGACGGCGCCTGGGGCGAGAAGGCGCGCTGGACCGACTTCGTGCCGCACCGGGCCGACGTGTTCAT
CCAGGACTTCCGGCTGTTCGACACCTTCACCGCGATCGAGGAGCGTTCGGGCGGACTGAAGCGGCTGCGGCTGCTGAAGC
CCGATGGGGGCTCGGAGTTCGTGGCGGCGGACGAGCCGGCCTACACCATGGGCTTCGGGACCAACGCCGAGGCCGACTCC
ACGGCGCTGCGCTACACCTACACCTCGCTGACCACGCCGCTGTCGACCTATGACCTGGACCTGGCCACCGGCAAGCGCAC
CCTGCTGAAGCAGACCCCGGTGATCGGCTACGATCCCTCGCAGTACGTGACCGAGCGCGTCTGGGCCCCGGCCCGCGACG
GGACGAAGATCCCGGTCTCGCTGGTCTACCGGAAGGGCTTCAAGCGCGACGGGACCGCGCCGCTGTTCCAGTACGCCTAC
GGCAGCTACGGCATCTCGATGGACCCGGCGTTCAACCTGCCGGCGGTGAGCCTGCTGGACCGCGGGGTCGTCTACGCCAT
CGCCCACATCCGCGGCGGCCAGGAGATGGGCCGCAAGTGGTACGACGACGGCAAGCTGCTGAAGAAGCAGAACACCTTCA
ACGACTTCGTGGACGTCACCCGCCACCTCGTCGCCAAGAAGTACGCGGCCAGGGAGCGGGTGGGCGCCATGGGCGGCTCG
GCCGGCGGCCTGCTGATGGGGGCGGTGGCCAACCAGGCGCCGCAGGACTACCGGGTGATCGTCACCCAGGTGCCGTTCGT
GGACGTGGTCACGACCATGCTCGACGAGTCGATCCCGCTGACCACCAACGAGTTCGACGAGTGGGGCAACCCGAAGGACC
CGGCCTACTACCGCTACATGCTGGGCTACTCGCCGTACGACAACATCAAGGCCCAGGCCTATCCGGCGATCTTCGTGGGC
ACCGGCCTGTGGGACAGCCAGGTGCAGTACTACGAGCCGGCCAAGTACGTGGCGCGGCTGCGCGAGACCAAGACCGACGA
CAATCCGCTGGTCTTCCGGGTGAACATGGAGGCCGGCCACGGCGGCAAGTCGGGCCGCTTCCGCCGCTACGAGGAGATGG
CGGAGTACTACGCCTTCGTGCTGGACCAGCTCGGGGGGAAGTAG

Upstream 100 bases:

>100_bases
CAATCGTAGCACGGGAATTCAACCGGCGCGGCGGCTTGCGGGACGAAGGAACGCATGCCAGCGTCCGCCGCCTCTCGGTC
GTGGGGAATTTCGGAACACC

Downstream 100 bases:

>100_bases
GGCGTCAGGCCGGCCGCCCCGTCCCGGATGTGTCCCAGGGAAGCGGCCGGCCGAGGCGCACGCGGGCCGCGTCGATCTCG
CAGCCGTAGACCAGCACCTC

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MRIATFAAAAAVLLAGAAQAQAQTQPTTPEPPRAAKRPHEVKAPGGTRTDEYYWLRDDTRKNPEMLAHLAAENAYADAVL
AANKPLKEALYKEIVGRVKQDDASVPYRERGYWYYTRFEAGKDYPILARRKGEMTAPEEILLEQNAMAQGKGYFNVGEAV
VSQDNRLLAWAEDTVGRRQYVLKVKDLATGQVLSDTVENIEPNIVWADDNRTIFYIEKDPVTLLSKRVKAHVLGTPASAD
RLVYEEADDSFYMGLGRTRSDKYLCVLLQSTTATEQRCTPAAAPGALQVVAPRERDHLYQADHLAGRWVIRTNWDAPNYR
LMQAPDGAWGEKARWTDFVPHRADVFIQDFRLFDTFTAIEERSGGLKRLRLLKPDGGSEFVAADEPAYTMGFGTNAEADS
TALRYTYTSLTTPLSTYDLDLATGKRTLLKQTPVIGYDPSQYVTERVWAPARDGTKIPVSLVYRKGFKRDGTAPLFQYAY
GSYGISMDPAFNLPAVSLLDRGVVYAIAHIRGGQEMGRKWYDDGKLLKKQNTFNDFVDVTRHLVAKKYAARERVGAMGGS
AGGLLMGAVANQAPQDYRVIVTQVPFVDVVTTMLDESIPLTTNEFDEWGNPKDPAYYRYMLGYSPYDNIKAQAYPAIFVG
TGLWDSQVQYYEPAKYVARLRETKTDDNPLVFRVNMEAGHGGKSGRFRRYEEMAEYYAFVLDQLGGK

Sequences:

>Translated_707_residues
MRIATFAAAAAVLLAGAAQAQAQTQPTTPEPPRAAKRPHEVKAPGGTRTDEYYWLRDDTRKNPEMLAHLAAENAYADAVL
AANKPLKEALYKEIVGRVKQDDASVPYRERGYWYYTRFEAGKDYPILARRKGEMTAPEEILLEQNAMAQGKGYFNVGEAV
VSQDNRLLAWAEDTVGRRQYVLKVKDLATGQVLSDTVENIEPNIVWADDNRTIFYIEKDPVTLLSKRVKAHVLGTPASAD
RLVYEEADDSFYMGLGRTRSDKYLCVLLQSTTATEQRCTPAAAPGALQVVAPRERDHLYQADHLAGRWVIRTNWDAPNYR
LMQAPDGAWGEKARWTDFVPHRADVFIQDFRLFDTFTAIEERSGGLKRLRLLKPDGGSEFVAADEPAYTMGFGTNAEADS
TALRYTYTSLTTPLSTYDLDLATGKRTLLKQTPVIGYDPSQYVTERVWAPARDGTKIPVSLVYRKGFKRDGTAPLFQYAY
GSYGISMDPAFNLPAVSLLDRGVVYAIAHIRGGQEMGRKWYDDGKLLKKQNTFNDFVDVTRHLVAKKYAARERVGAMGGS
AGGLLMGAVANQAPQDYRVIVTQVPFVDVVTTMLDESIPLTTNEFDEWGNPKDPAYYRYMLGYSPYDNIKAQAYPAIFVG
TGLWDSQVQYYEPAKYVARLRETKTDDNPLVFRVNMEAGHGGKSGRFRRYEEMAEYYAFVLDQLGGK
>Mature_707_residues
MRIATFAAAAAVLLAGAAQAQAQTQPTTPEPPRAAKRPHEVKAPGGTRTDEYYWLRDDTRKNPEMLAHLAAENAYADAVL
AANKPLKEALYKEIVGRVKQDDASVPYRERGYWYYTRFEAGKDYPILARRKGEMTAPEEILLEQNAMAQGKGYFNVGEAV
VSQDNRLLAWAEDTVGRRQYVLKVKDLATGQVLSDTVENIEPNIVWADDNRTIFYIEKDPVTLLSKRVKAHVLGTPASAD
RLVYEEADDSFYMGLGRTRSDKYLCVLLQSTTATEQRCTPAAAPGALQVVAPRERDHLYQADHLAGRWVIRTNWDAPNYR
LMQAPDGAWGEKARWTDFVPHRADVFIQDFRLFDTFTAIEERSGGLKRLRLLKPDGGSEFVAADEPAYTMGFGTNAEADS
TALRYTYTSLTTPLSTYDLDLATGKRTLLKQTPVIGYDPSQYVTERVWAPARDGTKIPVSLVYRKGFKRDGTAPLFQYAY
GSYGISMDPAFNLPAVSLLDRGVVYAIAHIRGGQEMGRKWYDDGKLLKKQNTFNDFVDVTRHLVAKKYAARERVGAMGGS
AGGLLMGAVANQAPQDYRVIVTQVPFVDVVTTMLDESIPLTTNEFDEWGNPKDPAYYRYMLGYSPYDNIKAQAYPAIFVG
TGLWDSQVQYYEPAKYVARLRETKTDDNPLVFRVNMEAGHGGKSGRFRRYEEMAEYYAFVLDQLGGK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=709, Percent_Identity=25.3878702397743, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI284172438, Length=426, Percent_Identity=27.4647887323944, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI284172431, Length=426, Percent_Identity=27.4647887323944, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI284172420, Length=426, Percent_Identity=27.4647887323944, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI284172413, Length=426, Percent_Identity=27.4647887323944, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI70778815, Length=426, Percent_Identity=27.4647887323944, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI108860686, Length=281, Percent_Identity=31.6725978647687, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI108860692, Length=212, Percent_Identity=33.9622641509434, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1788150, Length=674, Percent_Identity=46.2908011869436, Blast_Score=626, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24583414, Length=707, Percent_Identity=25.035360678925, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI221510989, Length=683, Percent_Identity=24.3045387994143, Blast_Score=174, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 79222; Mature: 79222

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIATFAAAAAVLLAGAAQAQAQTQPTTPEPPRAAKRPHEVKAPGGTRTDEYYWLRDDTR
CCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEECCCCC
KNPEMLAHLAAENAYADAVLAANKPLKEALYKEIVGRVKQDDASVPYRERGYWYYTRFEA
CCHHHHHHHHHCCHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEECC
GKDYPILARRKGEMTAPEEILLEQNAMAQGKGYFNVGEAVVSQDNRLLAWAEDTVGRRQY
CCCCCEEEECCCCCCCCHHHHHCCCHHHCCCCCEEHHHHHHCCCCEEEEEECCCCCCEEE
VLKVKDLATGQVLSDTVENIEPNIVWADDNRTIFYIEKDPVTLLSKRVKAHVLGTPASAD
EEEEECCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHEEECCCCCCC
RLVYEEADDSFYMGLGRTRSDKYLCVLLQSTTATEQRCTPAAAPGALQVVAPRERDHLYQ
CEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCHHCCCCCCCCCEEEEECCCCHHHHHH
ADHLAGRWVIRTNWDAPNYRLMQAPDGAWGEKARWTDFVPHRADVFIQDFRLFDTFTAIE
HHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERSGGLKRLRLLKPDGGSEFVAADEPAYTMGFGTNAEADSTALRYTYTSLTTPLSTYDLD
HHCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCEEEEEEHHHCCCCCCEEEE
LATGKRTLLKQTPVIGYDPSQYVTERVWAPARDGTKIPVSLVYRKGFKRDGTAPLFQYAY
CCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHHH
GSYGISMDPAFNLPAVSLLDRGVVYAIAHIRGGQEMGRKWYDDGKLLKKQNTFNDFVDVT
CCCCCCCCCCCCCCHHHHHHCCCEEEEEHHCCCHHHHHHCCCCCCEEECCCCHHHHHHHH
RHLVAKKYAARERVGAMGGSAGGLLMGAVANQAPQDYRVIVTQVPFVDVVTTMLDESIPL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCC
TTNEFDEWGNPKDPAYYRYMLGYSPYDNIKAQAYPAIFVGTGLWDSQVQYYEPAKYVARL
CCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHCCHHHHHHHH
RETKTDDNPLVFRVNMEAGHGGKSGRFRRYEEMAEYYAFVLDQLGGK
HHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIATFAAAAAVLLAGAAQAQAQTQPTTPEPPRAAKRPHEVKAPGGTRTDEYYWLRDDTR
CCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEECCCCC
KNPEMLAHLAAENAYADAVLAANKPLKEALYKEIVGRVKQDDASVPYRERGYWYYTRFEA
CCHHHHHHHHHCCHHHHHHEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEECC
GKDYPILARRKGEMTAPEEILLEQNAMAQGKGYFNVGEAVVSQDNRLLAWAEDTVGRRQY
CCCCCEEEECCCCCCCCHHHHHCCCHHHCCCCCEEHHHHHHCCCCEEEEEECCCCCCEEE
VLKVKDLATGQVLSDTVENIEPNIVWADDNRTIFYIEKDPVTLLSKRVKAHVLGTPASAD
EEEEECCCCCHHHHHHHHCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHEEECCCCCCC
RLVYEEADDSFYMGLGRTRSDKYLCVLLQSTTATEQRCTPAAAPGALQVVAPRERDHLYQ
CEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCHHCCCCCCCCCEEEEECCCCHHHHHH
ADHLAGRWVIRTNWDAPNYRLMQAPDGAWGEKARWTDFVPHRADVFIQDFRLFDTFTAIE
HHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ERSGGLKRLRLLKPDGGSEFVAADEPAYTMGFGTNAEADSTALRYTYTSLTTPLSTYDLD
HHCCCCEEEEEECCCCCCCEEECCCCCEEECCCCCCCCCCCEEEEEEHHHCCCCCCEEEE
LATGKRTLLKQTPVIGYDPSQYVTERVWAPARDGTKIPVSLVYRKGFKRDGTAPLFQYAY
CCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCCCHHHHHHH
GSYGISMDPAFNLPAVSLLDRGVVYAIAHIRGGQEMGRKWYDDGKLLKKQNTFNDFVDVT
CCCCCCCCCCCCCCHHHHHHCCCEEEEEHHCCCHHHHHHCCCCCCEEECCCCHHHHHHHH
RHLVAKKYAARERVGAMGGSAGGLLMGAVANQAPQDYRVIVTQVPFVDVVTTMLDESIPL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCC
TTNEFDEWGNPKDPAYYRYMLGYSPYDNIKAQAYPAIFVGTGLWDSQVQYYEPAKYVARL
CCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHCCHHHHHHHH
RETKTDDNPLVFRVNMEAGHGGKSGRFRRYEEMAEYYAFVLDQLGGK
HHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]