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The map label for this gene is fabG [H]

Identifier: 197104425

GI number: 197104425

Start: 1055849

End: 1056619

Strand: Reverse

Name: fabG [H]

Synonym: PHZ_c0959

Alternate gene names: 197104425

Gene position: 1056619-1055849 (Counterclockwise)

Preceding gene: 197104428

Following gene: 197104422

Centisome position: 26.44

GC content: 74.84

Gene sequence:

>771_bases
TTGCCAGGGCCGCCGGCGGCGGCGAAGAGGGCGGCGAAGTCCGTTCGGGAGAGTCCCGCCTTGGCCCCGCACATCCTCGT
CACCGGCTCCACCCGCGGCATCGGCGCCGCGATCCAGGCGGCGCTCGCGGCGAAAGGCGCCCGCGTGGTCGGGCACGGCC
GCACCGACGGGCCGGGGGTGATCGGCGCCGACCTCGCCGACCCGGGCGCGGGTGACGTCCTGTGGGACCGCGCGCTGGCG
GCGCTGGACGGGCGGATCGACGTGCTGGTCAACAACGCCGGGGTGTTCGAGGCCGTCGCCGTGGACGCGCCGGCCGAGGA
CTGGCAGGGCGCCTGGAGCCGGACGATGCAGATCAACCTGCAGGCCTCGGCCGATCTCTGCCGGCGGGCGGTCCTGCACT
TCCGCGAGCAAGGGCGCGGGGGCCGGATCGTCAACATCGCCAGCCGCGCGGCCTATCGCGGCGACAGTCCGGCCCACTGG
CACTACGCCGCGTCGAAGGCCGGCATGGTGGGCATGACCAAGTCCATCGCCCGCGGCTACGCCCGCGAGGAGATCCTGGC
CTTCGCCGTCTGCCCGGGCTTCGTGATGACCGGCATGGCCGACGAGTACCTGGCGAGCCGCGGCGGCGACAAGCTGCTGG
CCGACATCCCCCTGGGCCGGGTGGCCAGCCCCGAGGAGGTCGCGAGCGTGGCCGCCTACCTCGCCCTGGAGGCGCCCGCC
TCGATGACGGGCGCGGTCCTGGACGTGAACGGCGCCAGCTTCGTGCGCTGA

Upstream 100 bases:

>100_bases
CTATGGGACGGCGCCCAGGCCGATTTGCGGGGCAGGAGCGGCCGACCTGCGGCGAGATGCCGCAGCCTCTGGCGCGGCCG
GCCAGACGGGCCCGGCGGGC

Downstream 100 bases:

>100_bases
GGCGGGCGCTAGGCCAGCGCCCGCTCGGTCGCCTCGATCTCGTCCTTGATCCAGTCGTGGCCGGTGGTCACCAGCACGCC
CTCGATCGCCGAGATGTGGC

Product: short-chain alcohol dehydrogenase-like protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPGPPAAAKRAAKSVRESPALAPHILVTGSTRGIGAAIQAALAAKGARVVGHGRTDGPGVIGADLADPGAGDVLWDRALA
ALDGRIDVLVNNAGVFEAVAVDAPAEDWQGAWSRTMQINLQASADLCRRAVLHFREQGRGGRIVNIASRAAYRGDSPAHW
HYAASKAGMVGMTKSIARGYAREEILAFAVCPGFVMTGMADEYLASRGGDKLLADIPLGRVASPEEVASVAAYLALEAPA
SMTGAVLDVNGASFVR

Sequences:

>Translated_256_residues
MPGPPAAAKRAAKSVRESPALAPHILVTGSTRGIGAAIQAALAAKGARVVGHGRTDGPGVIGADLADPGAGDVLWDRALA
ALDGRIDVLVNNAGVFEAVAVDAPAEDWQGAWSRTMQINLQASADLCRRAVLHFREQGRGGRIVNIASRAAYRGDSPAHW
HYAASKAGMVGMTKSIARGYAREEILAFAVCPGFVMTGMADEYLASRGGDKLLADIPLGRVASPEEVASVAAYLALEAPA
SMTGAVLDVNGASFVR
>Mature_255_residues
PGPPAAAKRAAKSVRESPALAPHILVTGSTRGIGAAIQAALAAKGARVVGHGRTDGPGVIGADLADPGAGDVLWDRALAA
LDGRIDVLVNNAGVFEAVAVDAPAEDWQGAWSRTMQINLQASADLCRRAVLHFREQGRGGRIVNIASRAAYRGDSPAHWH
YAASKAGMVGMTKSIARGYAREEILAFAVCPGFVMTGMADEYLASRGGDKLLADIPLGRVASPEEVASVAAYLALEAPAS
MTGAVLDVNGASFVR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=32.5, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=30.3501945525292, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=173, Percent_Identity=31.2138728323699, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=30.1526717557252, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI126723750, Length=277, Percent_Identity=27.4368231046931, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.1967213114754, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=29.7959183673469, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=32, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=31.0483870967742, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=30.8, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.6, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=27.6, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=32.5, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=239, Percent_Identity=30.9623430962343, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=250, Percent_Identity=29.6, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=28.4, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=26.9709543568465, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=240, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=29.2887029288703, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=27.1966527196653, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=29.8755186721992, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=30.2904564315353, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=247, Percent_Identity=29.9595141700405, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=250, Percent_Identity=29.2, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=249, Percent_Identity=30.1204819277108, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=252, Percent_Identity=29.3650793650794, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=26.0700389105058, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=241, Percent_Identity=30.7053941908714, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=239, Percent_Identity=27.1966527196653, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=242, Percent_Identity=26.8595041322314, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=28.8973384030418, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.2258064516129, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355319, Length=235, Percent_Identity=28.5106382978723, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=30.3643724696356, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=28.8537549407115, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=29.8387096774194, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=25.3112033195021, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26362; Mature: 26231

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGPPAAAKRAAKSVRESPALAPHILVTGSTRGIGAAIQAALAAKGARVVGHGRTDGPGV
CCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCE
IGADLADPGAGDVLWDRALAALDGRIDVLVNNAGVFEAVAVDAPAEDWQGAWSRTMQINL
EECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCHHHCCCCCEEEEEEE
QASADLCRRAVLHFREQGRGGRIVNIASRAAYRGDSPAHWHYAASKAGMVGMTKSIARGY
ECHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCCEEEHHCCCCCHHHHHHHHHHH
AREEILAFAVCPGFVMTGMADEYLASRGGDKLLADIPLGRVASPEEVASVAAYLALEAPA
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
SMTGAVLDVNGASFVR
CCCCEEEEECCCCCCC
>Mature Secondary Structure 
PGPPAAAKRAAKSVRESPALAPHILVTGSTRGIGAAIQAALAAKGARVVGHGRTDGPGV
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCE
IGADLADPGAGDVLWDRALAALDGRIDVLVNNAGVFEAVAVDAPAEDWQGAWSRTMQINL
EECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCHHHCCCCCEEEEEEE
QASADLCRRAVLHFREQGRGGRIVNIASRAAYRGDSPAHWHYAASKAGMVGMTKSIARGY
ECHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCCCCCCCEEEHHCCCCCHHHHHHHHHHH
AREEILAFAVCPGFVMTGMADEYLASRGGDKLLADIPLGRVASPEEVASVAAYLALEAPA
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
SMTGAVLDVNGASFVR
CCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]