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The map label for this gene is cobS [H]

Identifier: 197104193

GI number: 197104193

Start: 798252

End: 799253

Strand: Reverse

Name: cobS [H]

Synonym: PHZ_c0727

Alternate gene names: 197104193

Gene position: 799253-798252 (Counterclockwise)

Preceding gene: 197104196

Following gene: 197104192

Centisome position: 20.0

GC content: 66.67

Gene sequence:

>1002_bases
ATGGCCGCTTTCGACACCACCGAAGACAAGCTGATCTCCCTGGTCCCGGACAAGGAGGTCGACGCCCGCGAGACCTTCGG
CGTGGACTTCGACATGAAGGTCCCCGCGTTCTCCGAGCGCGACCCGCACGTCCCCGACGTCGATCCGGCCTACAAGTTCG
ACCCCGAGACCACCCGAGCGATCCTGGCGGGCTTCGCCTTCGATCGCCGCGTCATGGTCCAGGGCTATCACGGCACCGGC
AAGTCCACCCACATCGAGCAGGTGGCCGCGCGGCTCAACTGGCCGATGATCCGGGTCAACCTCGACAGCCACATCAGCCG
GATCGACCTGGTCGGCAAGGACGCCATCGTCCTGAAGGAAGGCAAGCAGGTCACCGAGTTCCGCGAGGGCATCCTGCCCT
GGGCCATTCAGCGGCCCATCGCCCTGGTGTTCGACGAGTACGACGCCGGCCGGCCGGACGTGATGTTCGTGATCCAGCGG
GTGCTGGAGGCCGCGGGCAAGCTCACCCTGCTCGACCAGAACCGGGTGATCCGCTCGAACCCCTACTTCCGGCTGTTCTC
GACGACCAACACCATCGGCCTGGGCGACACCACCGGCCTCTACCACGGCACCCAGCAGATCAATCAGGCGCAGATGGACC
GCTGGTCCATCGTCACCACGCTCAACTACCTGAGCCACGACGTCGAGGCGGCCATCGTGCTGGCCAAGGCGCCCGCCTAC
GACACGCCCGAGGGCAAGCGGACCATCGCGGCCATGGTGCGCGTGGCCGACATGACCCGGAACGCCTTCATGAACGGCGA
CATCTCGACGGTCATGAGCCCGCGTACGGTGATCACCTGGGCCCAGAACGCCGAGATCTTCGGCGGCGACATCGCCCTGG
CCTTCCGCATGACCTTCCTGAACAAGTGCGACGAGCTGGAGCGCGGCACCGTCGCCGAGTTCTTCCAGCGCGCCTTCGGC
CAGGACCTGCCGGAAAGCACCGCCCGGGTGCGGGTGGCCTAA

Upstream 100 bases:

>100_bases
CGTCGTTCCTCCCGTTTGCGTCGGCGCCTCTTCGCGGGCGCGCCTGCTCTAGAAACACCCGTTTGCTTCCGCCCCGGCAA
GCCTGTAATCCGGACCCGCC

Downstream 100 bases:

>100_bases
GGCCGCTGGACGGCGGCCCTCCGCGCCGCCATCATCAAACCCGGTTTTCGAAAAACGACCGGGGAGGACTTCCGATGATC
AGGACGCTTGCGAGCGCCGC

Product: cobalamin biosynthesis protein

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAAFDTTEDKLISLVPDKEVDARETFGVDFDMKVPAFSERDPHVPDVDPAYKFDPETTRAILAGFAFDRRVMVQGYHGTG
KSTHIEQVAARLNWPMIRVNLDSHISRIDLVGKDAIVLKEGKQVTEFREGILPWAIQRPIALVFDEYDAGRPDVMFVIQR
VLEAAGKLTLLDQNRVIRSNPYFRLFSTTNTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLSHDVEAAIVLAKAPAY
DTPEGKRTIAAMVRVADMTRNAFMNGDISTVMSPRTVITWAQNAEIFGGDIALAFRMTFLNKCDELERGTVAEFFQRAFG
QDLPESTARVRVA

Sequences:

>Translated_333_residues
MAAFDTTEDKLISLVPDKEVDARETFGVDFDMKVPAFSERDPHVPDVDPAYKFDPETTRAILAGFAFDRRVMVQGYHGTG
KSTHIEQVAARLNWPMIRVNLDSHISRIDLVGKDAIVLKEGKQVTEFREGILPWAIQRPIALVFDEYDAGRPDVMFVIQR
VLEAAGKLTLLDQNRVIRSNPYFRLFSTTNTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLSHDVEAAIVLAKAPAY
DTPEGKRTIAAMVRVADMTRNAFMNGDISTVMSPRTVITWAQNAEIFGGDIALAFRMTFLNKCDELERGTVAEFFQRAFG
QDLPESTARVRVA
>Mature_332_residues
AAFDTTEDKLISLVPDKEVDARETFGVDFDMKVPAFSERDPHVPDVDPAYKFDPETTRAILAGFAFDRRVMVQGYHGTGK
STHIEQVAARLNWPMIRVNLDSHISRIDLVGKDAIVLKEGKQVTEFREGILPWAIQRPIALVFDEYDAGRPDVMFVIQRV
LEAAGKLTLLDQNRVIRSNPYFRLFSTTNTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLSHDVEAAIVLAKAPAYD
TPEGKRTIAAMVRVADMTRNAFMNGDISTVMSPRTVITWAQNAEIFGGDIALAFRMTFLNKCDELERGTVAEFFQRAFGQ
DLPESTARVRVA

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 37309; Mature: 37178

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFDTTEDKLISLVPDKEVDARETFGVDFDMKVPAFSERDPHVPDVDPAYKFDPETTRA
CCCCCCCCCCEEEECCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ILAGFAFDRRVMVQGYHGTGKSTHIEQVAARLNWPMIRVNLDSHISRIDLVGKDAIVLKE
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEEC
GKQVTEFREGILPWAIQRPIALVFDEYDAGRPDVMFVIQRVLEAAGKLTLLDQNRVIRSN
CCHHHHHHHCCCCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECC
PYFRLFSTTNTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLSHDVEAAIVLAKAPAY
CCEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
DTPEGKRTIAAMVRVADMTRNAFMNGDISTVMSPRTVITWAQNAEIFGGDIALAFRMTFL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCEEECCHHHHHHHHHHH
NKCDELERGTVAEFFQRAFGQDLPESTARVRVA
HHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECC
>Mature Secondary Structure 
AAFDTTEDKLISLVPDKEVDARETFGVDFDMKVPAFSERDPHVPDVDPAYKFDPETTRA
CCCCCCCCCEEEECCCCCCCCHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCHHHHH
ILAGFAFDRRVMVQGYHGTGKSTHIEQVAARLNWPMIRVNLDSHISRIDLVGKDAIVLKE
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCEEEEEC
GKQVTEFREGILPWAIQRPIALVFDEYDAGRPDVMFVIQRVLEAAGKLTLLDQNRVIRSN
CCHHHHHHHCCCCHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEECC
PYFRLFSTTNTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLSHDVEAAIVLAKAPAY
CCEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCC
DTPEGKRTIAAMVRVADMTRNAFMNGDISTVMSPRTVITWAQNAEIFGGDIALAFRMTFL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCEEECCHHHHHHHHHHH
NKCDELERGTVAEFFQRAFGQDLPESTARVRVA
HHHHHCCCCCHHHHHHHHHCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]