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The map label for this gene is luxQ [H]

Identifier: 197104132

GI number: 197104132

Start: 717741

End: 719357

Strand: Reverse

Name: luxQ [H]

Synonym: PHZ_c0666

Alternate gene names: 197104132

Gene position: 719357-717741 (Counterclockwise)

Preceding gene: 197104133

Following gene: 197104131

Centisome position: 18.0

GC content: 73.22

Gene sequence:

>1617_bases
ATGGCCCTGCTGCTCGACATCGCCCCCTGCGTCCCGCCGGTCTTCTCCACCGCCACCGGCGGCGAGCTCTACCGGCGCTT
CGAGTCCGAGCCGGACACCCTGGCCATCGCGGTCGTGGACGCCGCGGGCCGGCCGATCGGCATCGTCGAGCGCAACAGCT
TCCTGGTCCGCATGGCCGCCCAGTACGGCCACGCCCTGTGGTCGCGGCGGCCGATCGCCGGCTGGATGAAGACCGACCCG
CTGGTGGCCGACGGCGACGTCACGGTCTCGGAGTTCTGCGGCCGGATCCTCGAGGAGCGCCCGTCCGAGCTGCTGCACGG
CTTCATCGTCACCTGCGGCGGGCGCTACGCCGGAGTCGGCACCATGCTGGCCCTGTTGCAGGCGTCCGCCGCCGAGACCG
CGTCCCACGCCGGAGAGATGACCCGCCTGGCCGAGGCCGCCCGGGCGTCCAGCGCCCAGGCCCACGAGGCGCTGGCCGCC
AAGGCCCGCTTCCTGGCGGTGATGAGCCACGAGATCCGCACGCCGCTGAACGGCGTGCTTGGCGTCGCCGAGATCCTGCG
GCGCAAGCTGCCGGACGCCGAGCTCGCGCCCCTGGTCAACACCATCATCGAGTCCGGCGGCGTGCTGCTCCGCCTGCTGA
ACGATGCGCTCGACCTCTCGCGCGCCGAGGCGGCGGGGCTGGAACTGGACGAGGCGCCGCTGCCCGTCGCCGAACTCCTG
GACGACGTGCTCGCGCTCTGGACGCCGCAGGCCGACATCAGGGGCGTTCCGCTCACCGGCGCCTACGACGGCCCGCAGGA
CCTCTGGGTTCTCGGAGACCGGGTCCGCCTGCGCCAGATCCTCAACAACCTGGTGGGGAACGGGCTGAAGTTCACCGGCG
CCGGCGGCGTCCACGTGCGCCTGACGGCGCGGACCGAGGGCGACTGCGTGCGGCTGGCCGGCGCTGTATCGGACTCAGGG
CCAGGCGTTCCCCCCGAGCGGCTGGAGACCATCTTCCAGCCCTTCCAGCAGACGGAGGAGGGCGTCCGACGGGGCGGCGC
GGGCCTCGGCCTGGCGGTCTGCCGCCAAATCGTCCAGCGGATGGACGGAACCATCCAGGCCCGCAACCGGCCGGAAGGCG
GCGCGGAGTTCGCGTTCGAGACGCCGCTCTTCCGCGTGCCGGCGCCAAGCTCCGTTGGCGGAGCGACGGCCGAGCCGCCG
CCCGGCGTCGAGGGCCGCGTCCACGTGCTGATCGCCGACGACAACGCGACCAACCGGCTGGTCGCGGCCAGCCTCTGCGA
GACCTTCGGCTGCACCAGCGAATGCGTCGAGGACGGCGCGGCCGCCGTCGAGGCCGCCGCCTCCGGCCGCTTCGACCTGA
TCCTCATGGACATCAAGATGCCGGTGATGGACGGCGCCGAAGCGACCCGCCGAATCCGCTCGGGCGCCGGGGCGGGCTCG
CGGACGCCGATCCTGGCGCTGACCGCCAACGCCGATCCGGCGGACGCGGCCTTCTACCGCCGCTGCGGCGTAAACGGAGT
GGTGGAAAAGCCCATCCGGCCCGATCGCCTGCTGGCCGCCATGACGGCGGTGCTGAACCTGGTCGCCGCCGAGTCGGACG
CCGTCACCGCGTGCTGA

Upstream 100 bases:

>100_bases
ACATAAGTTTCGCAAAACATTCATGAAATCGGGGCCCGGCCCTAACCGCTCGTTAGCCGCGCCCGGGGAGAACGGCGGGG
CTTTCCCGAACGCGCTCCCC

Downstream 100 bases:

>100_bases
CGAGCGCCCCGCCGTTGCGGATCAGCCGCACGCCGCGGCCCGACAGCACGTAGCGGCGGCCCGCGGCGCCCTCGGCAGGT
CCGGCGCGCCGCACCAGCCC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MALLLDIAPCVPPVFSTATGGELYRRFESEPDTLAIAVVDAAGRPIGIVERNSFLVRMAAQYGHALWSRRPIAGWMKTDP
LVADGDVTVSEFCGRILEERPSELLHGFIVTCGGRYAGVGTMLALLQASAAETASHAGEMTRLAEAARASSAQAHEALAA
KARFLAVMSHEIRTPLNGVLGVAEILRRKLPDAELAPLVNTIIESGGVLLRLLNDALDLSRAEAAGLELDEAPLPVAELL
DDVLALWTPQADIRGVPLTGAYDGPQDLWVLGDRVRLRQILNNLVGNGLKFTGAGGVHVRLTARTEGDCVRLAGAVSDSG
PGVPPERLETIFQPFQQTEEGVRRGGAGLGLAVCRQIVQRMDGTIQARNRPEGGAEFAFETPLFRVPAPSSVGGATAEPP
PGVEGRVHVLIADDNATNRLVAASLCETFGCTSECVEDGAAAVEAAASGRFDLILMDIKMPVMDGAEATRRIRSGAGAGS
RTPILALTANADPADAAFYRRCGVNGVVEKPIRPDRLLAAMTAVLNLVAAESDAVTAC

Sequences:

>Translated_538_residues
MALLLDIAPCVPPVFSTATGGELYRRFESEPDTLAIAVVDAAGRPIGIVERNSFLVRMAAQYGHALWSRRPIAGWMKTDP
LVADGDVTVSEFCGRILEERPSELLHGFIVTCGGRYAGVGTMLALLQASAAETASHAGEMTRLAEAARASSAQAHEALAA
KARFLAVMSHEIRTPLNGVLGVAEILRRKLPDAELAPLVNTIIESGGVLLRLLNDALDLSRAEAAGLELDEAPLPVAELL
DDVLALWTPQADIRGVPLTGAYDGPQDLWVLGDRVRLRQILNNLVGNGLKFTGAGGVHVRLTARTEGDCVRLAGAVSDSG
PGVPPERLETIFQPFQQTEEGVRRGGAGLGLAVCRQIVQRMDGTIQARNRPEGGAEFAFETPLFRVPAPSSVGGATAEPP
PGVEGRVHVLIADDNATNRLVAASLCETFGCTSECVEDGAAAVEAAASGRFDLILMDIKMPVMDGAEATRRIRSGAGAGS
RTPILALTANADPADAAFYRRCGVNGVVEKPIRPDRLLAAMTAVLNLVAAESDAVTAC
>Mature_537_residues
ALLLDIAPCVPPVFSTATGGELYRRFESEPDTLAIAVVDAAGRPIGIVERNSFLVRMAAQYGHALWSRRPIAGWMKTDPL
VADGDVTVSEFCGRILEERPSELLHGFIVTCGGRYAGVGTMLALLQASAAETASHAGEMTRLAEAARASSAQAHEALAAK
ARFLAVMSHEIRTPLNGVLGVAEILRRKLPDAELAPLVNTIIESGGVLLRLLNDALDLSRAEAAGLELDEAPLPVAELLD
DVLALWTPQADIRGVPLTGAYDGPQDLWVLGDRVRLRQILNNLVGNGLKFTGAGGVHVRLTARTEGDCVRLAGAVSDSGP
GVPPERLETIFQPFQQTEEGVRRGGAGLGLAVCRQIVQRMDGTIQARNRPEGGAEFAFETPLFRVPAPSSVGGATAEPPP
GVEGRVHVLIADDNATNRLVAASLCETFGCTSECVEDGAAAVEAAASGRFDLILMDIKMPVMDGAEATRRIRSGAGAGSR
TPILALTANADPADAAFYRRCGVNGVVEKPIRPDRLLAAMTAVLNLVAAESDAVTAC

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=388, Percent_Identity=28.8659793814433, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI48994928, Length=386, Percent_Identity=32.6424870466321, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=32.258064516129, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789149, Length=380, Percent_Identity=30.7894736842105, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=31.5789473684211, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=32.9457364341085, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786912, Length=293, Percent_Identity=32.0819112627986, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=31.496062992126, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=31.8965517241379, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=29.8701298701299, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=29.9212598425197, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=27.3109243697479, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=27.3504273504274, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=32, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=223, Percent_Identity=30.4932735426009, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=118, Percent_Identity=36.4406779661017, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322044, Length=70, Percent_Identity=41.4285714285714, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56562; Mature: 56431

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLLDIAPCVPPVFSTATGGELYRRFESEPDTLAIAVVDAAGRPIGIVERNSFLVRMAA
CEEEEECHHCCCCHHCCCCCHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHH
QYGHALWSRRPIAGWMKTDPLVADGDVTVSEFCGRILEERPSELLHGFIVTCGGRYAGVG
HHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHH
TMLALLQASAAETASHAGEMTRLAEAARASSAQAHEALAAKARFLAVMSHEIRTPLNGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GVAEILRRKLPDAELAPLVNTIIESGGVLLRLLNDALDLSRAEAAGLELDEAPLPVAELL
HHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DDVLALWTPQADIRGVPLTGAYDGPQDLWVLGDRVRLRQILNNLVGNGLKFTGAGGVHVR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEECCCCEEEE
LTARTEGDCVRLAGAVSDSGPGVPPERLETIFQPFQQTEEGVRRGGAGLGLAVCRQIVQR
EEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MDGTIQARNRPEGGAEFAFETPLFRVPAPSSVGGATAEPPPGVEGRVHVLIADDNATNRL
CCCCEEECCCCCCCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
VAASLCETFGCTSECVEDGAAAVEAAASGRFDLILMDIKMPVMDGAEATRRIRSGAGAGS
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCC
RTPILALTANADPADAAFYRRCGVNGVVEKPIRPDRLLAAMTAVLNLVAAESDAVTAC
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALLLDIAPCVPPVFSTATGGELYRRFESEPDTLAIAVVDAAGRPIGIVERNSFLVRMAA
EEEEECHHCCCCHHCCCCCHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHH
QYGHALWSRRPIAGWMKTDPLVADGDVTVSEFCGRILEERPSELLHGFIVTCGGRYAGVG
HHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHH
TMLALLQASAAETASHAGEMTRLAEAARASSAQAHEALAAKARFLAVMSHEIRTPLNGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
GVAEILRRKLPDAELAPLVNTIIESGGVLLRLLNDALDLSRAEAAGLELDEAPLPVAELL
HHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DDVLALWTPQADIRGVPLTGAYDGPQDLWVLGDRVRLRQILNNLVGNGLKFTGAGGVHVR
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEECCCCEEEE
LTARTEGDCVRLAGAVSDSGPGVPPERLETIFQPFQQTEEGVRRGGAGLGLAVCRQIVQR
EEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
MDGTIQARNRPEGGAEFAFETPLFRVPAPSSVGGATAEPPPGVEGRVHVLIADDNATNRL
CCCCEEECCCCCCCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
VAASLCETFGCTSECVEDGAAAVEAAASGRFDLILMDIKMPVMDGAEATRRIRSGAGAGS
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCC
RTPILALTANADPADAAFYRRCGVNGVVEKPIRPDRLLAAMTAVLNLVAAESDAVTAC
CCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA