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The map label for this gene is ycgJ [H]

Identifier: 197104090

GI number: 197104090

Start: 675268

End: 675888

Strand: Reverse

Name: ycgJ [H]

Synonym: PHZ_c0624

Alternate gene names: 197104090

Gene position: 675888-675268 (Counterclockwise)

Preceding gene: 197104091

Following gene: 197104087

Centisome position: 16.91

GC content: 71.82

Gene sequence:

>621_bases
ATGGCCTCGTTCTACGACCGGGTCATCCTGCCCAAGCTCCTGCAGTGCGCCTGCTCGGCGCCGCCGATGATGAAGCAGCG
CGAGAAGATCGTGCCGCAGGCCAGCGGCAAGGTGCTGGAGCTCGGCATCGGCATGGGGCTCAACCTCGCCTTCTACGATC
CGGGCAAGGTCGAGAGCGTCACGGGCGTCGATCCCGCCCCCGAGCTGCGCGCCGCCGCCCAGGCCGCCCCGCACGATCCG
CGCCTGAAGGTGGACGTGCAGGACGGGACCGCCGAGGCCTTGCCGTTCCCCGACAGGAGCTTCGACTGCGTGGTCTGCAC
GTTCACGCTCTGCTCGGTGCACACCCCGACCCAGGCCCTGGCCGAGGCCCGCAGGGTCCTGAAGCCCGGCGGCCGCCTCC
TCTACTGCGAGCACGGCCTGGCGCCCGACCCGGGCGTCGCGGCCTGGCAGCGGCGGGTGAACCCGGTCTGGAAGCGGATC
GCCGGCGGCTGCCACATCACTCGCCCGGTGACCTCGGCCATCGCGGCGGCGGGGTTCAAGGTCCGGCGCAGCGACAGCAT
GTACCTGCCGAAGACCCCGCGCATCCTGGGCTGGAACGAGTGGGGCGAGGCGACCGTCTGA

Upstream 100 bases:

>100_bases
CTCGGACGGATCATGCAAGCCATCTATGAGGCGGCGCGGACAGGCCGTACGGTGAAGCTGGCCTAGAAGCTGACCTGAGA
CGACGACAAGGGAGGACGCC

Downstream 100 bases:

>100_bases
CGAGGCGTTCTCCGAACATGAATTTTCGGTAACACCCCTTGAAATCGGAACACGTCACCGGCGTGACGGCGGCCAGGGGG
CATGTTGTTGCACGAATGGC

Product: SAM-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MASFYDRVILPKLLQCACSAPPMMKQREKIVPQASGKVLELGIGMGLNLAFYDPGKVESVTGVDPAPELRAAAQAAPHDP
RLKVDVQDGTAEALPFPDRSFDCVVCTFTLCSVHTPTQALAEARRVLKPGGRLLYCEHGLAPDPGVAAWQRRVNPVWKRI
AGGCHITRPVTSAIAAAGFKVRRSDSMYLPKTPRILGWNEWGEATV

Sequences:

>Translated_206_residues
MASFYDRVILPKLLQCACSAPPMMKQREKIVPQASGKVLELGIGMGLNLAFYDPGKVESVTGVDPAPELRAAAQAAPHDP
RLKVDVQDGTAEALPFPDRSFDCVVCTFTLCSVHTPTQALAEARRVLKPGGRLLYCEHGLAPDPGVAAWQRRVNPVWKRI
AGGCHITRPVTSAIAAAGFKVRRSDSMYLPKTPRILGWNEWGEATV
>Mature_205_residues
ASFYDRVILPKLLQCACSAPPMMKQREKIVPQASGKVLELGIGMGLNLAFYDPGKVESVTGVDPAPELRAAAQAAPHDPR
LKVDVQDGTAEALPFPDRSFDCVVCTFTLCSVHTPTQALAEARRVLKPGGRLLYCEHGLAPDPGVAAWQRRVNPVWKRIA
GGCHITRPVTSAIAAAGFKVRRSDSMYLPKTPRILGWNEWGEATV

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI164663805, Length=175, Percent_Identity=37.7142857142857, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI89145417, Length=176, Percent_Identity=31.25, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22345; Mature: 22214

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFYDRVILPKLLQCACSAPPMMKQREKIVPQASGKVLELGIGMGLNLAFYDPGKVESV
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCEE
TGVDPAPELRAAAQAAPHDPRLKVDVQDGTAEALPFPDRSFDCVVCTFTLCSVHTPTQAL
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHCCCCCHHHH
AEARRVLKPGGRLLYCEHGLAPDPGVAAWQRRVNPVWKRIAGGCHITRPVTSAIAAAGFK
HHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHCEE
VRRSDSMYLPKTPRILGWNEWGEATV
EECCCCEECCCCCCEECCCCCCCCCC
>Mature Secondary Structure 
ASFYDRVILPKLLQCACSAPPMMKQREKIVPQASGKVLELGIGMGLNLAFYDPGKVESV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCCEE
TGVDPAPELRAAAQAAPHDPRLKVDVQDGTAEALPFPDRSFDCVVCTFTLCSVHTPTQAL
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEHHHCCCCCHHHH
AEARRVLKPGGRLLYCEHGLAPDPGVAAWQRRVNPVWKRIAGGCHITRPVTSAIAAAGFK
HHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHCEE
VRRSDSMYLPKTPRILGWNEWGEATV
EECCCCEECCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]