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The map label for this gene is grp [H]

Identifier: 197104070

GI number: 197104070

Start: 645088

End: 645735

Strand: Reverse

Name: grp [H]

Synonym: PHZ_c0604

Alternate gene names: 197104070

Gene position: 645735-645088 (Counterclockwise)

Preceding gene: 197104072

Following gene: 197104069

Centisome position: 16.16

GC content: 64.2

Gene sequence:

>648_bases
GTGGCGCATCGCAATTTTCTTCCTTTCGGGCCTTCCTCCAGCCCTGCAAGATCATATAGGTTCCGGGGAATTGCTTACCA
AAACCATGCCCCGGCCAGCCGGTTCCGGGGCAAGAACCACGCCCATATCCGCCCGCAGAAGGAGGAAAAGTTGTCTGAGG
CCCTCGACGCCGTGGATGCCAAGATCCTGGATCTCATCCAGCACGACGCCGGATTGTCGGTCGCCGAGATCGCCGATCGC
GTGGGCCTGTCCTCCAGTCCCTGCTGGCGCCGGATCAAGCGCCTGGAGGACGCCGGCGTCATCCAGCGCCGCGTGACCAT
CCTCGACCGCGACAAGCTGGGCCTGGGCTTCGAGGTCTACTGCACGGTGAAGCTGTCGCTCCCGACCAAGGAGAACCTCG
ACTCGTTCGAGCAGGCGATCTTTAAGCTGCCCGAGGTGGTCCAGTGCGCCACCGTCACCGGCGCGGCCGACTACGAGCTG
CGCATCGTCACCCGCGACATGCACGCCTTCGACGACTTCCTGCGCGAGAAGATCCTCTCGCTGGGCCTCGTCTCCAACAT
CGAGAGCCGGATCGTCATCCGCTCGGTGAAGAACACCACCGCCGCCCCGCTGGGGCTGGTCAGCCCGTACGTGAGCGCGC
AAAGCTAG

Upstream 100 bases:

>100_bases
GCCGGCGCTGGTCCATCGCCACCCGGAGCAGAGTCTGCACCCCGGTGATGAAGACCCGGCCTTCGGTGAGCAGAAATTTG
TCGTCCAGCGTCACTTCGGC

Downstream 100 bases:

>100_bases
CCCGCCACCGACGGAGGGCTCCATGATCGACCTCGTCATCGACCAGCGGCGCAAGGACCTCGGCGGGTTCGAGGTCGGGC
GCGTCCTGCCCTTCGCCCAG

Product: transcriptional regulator, AsnC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAHRNFLPFGPSSSPARSYRFRGIAYQNHAPASRFRGKNHAHIRPQKEEKLSEALDAVDAKILDLIQHDAGLSVAEIADR
VGLSSSPCWRRIKRLEDAGVIQRRVTILDRDKLGLGFEVYCTVKLSLPTKENLDSFEQAIFKLPEVVQCATVTGAADYEL
RIVTRDMHAFDDFLREKILSLGLVSNIESRIVIRSVKNTTAAPLGLVSPYVSAQS

Sequences:

>Translated_215_residues
MAHRNFLPFGPSSSPARSYRFRGIAYQNHAPASRFRGKNHAHIRPQKEEKLSEALDAVDAKILDLIQHDAGLSVAEIADR
VGLSSSPCWRRIKRLEDAGVIQRRVTILDRDKLGLGFEVYCTVKLSLPTKENLDSFEQAIFKLPEVVQCATVTGAADYEL
RIVTRDMHAFDDFLREKILSLGLVSNIESRIVIRSVKNTTAAPLGLVSPYVSAQS
>Mature_214_residues
AHRNFLPFGPSSSPARSYRFRGIAYQNHAPASRFRGKNHAHIRPQKEEKLSEALDAVDAKILDLIQHDAGLSVAEIADRV
GLSSSPCWRRIKRLEDAGVIQRRVTILDRDKLGLGFEVYCTVKLSLPTKENLDSFEQAIFKLPEVVQCATVTGAADYELR
IVTRDMHAFDDFLREKILSLGLVSNIESRIVIRSVKNTTAAPLGLVSPYVSAQS

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=34, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787116, Length=146, Percent_Identity=33.5616438356164, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 23959; Mature: 23828

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHRNFLPFGPSSSPARSYRFRGIAYQNHAPASRFRGKNHAHIRPQKEEKLSEALDAVDA
CCCCCCCCCCCCCCCCHHHEECCEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KILDLIQHDAGLSVAEIADRVGLSSSPCWRRIKRLEDAGVIQRRVTILDRDKLGLGFEVY
HHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEE
CTVKLSLPTKENLDSFEQAIFKLPEVVQCATVTGAADYELRIVTRDMHAFDDFLREKILS
EEEEEECCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
LGLVSNIESRIVIRSVKNTTAAPLGLVSPYVSAQS
HHHHHHHHHHEEEEECCCCCCCCHHHHCCHHCCCC
>Mature Secondary Structure 
AHRNFLPFGPSSSPARSYRFRGIAYQNHAPASRFRGKNHAHIRPQKEEKLSEALDAVDA
CCCCCCCCCCCCCCCHHHEECCEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
KILDLIQHDAGLSVAEIADRVGLSSSPCWRRIKRLEDAGVIQRRVTILDRDKLGLGFEVY
HHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEE
CTVKLSLPTKENLDSFEQAIFKLPEVVQCATVTGAADYELRIVTRDMHAFDDFLREKILS
EEEEEECCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
LGLVSNIESRIVIRSVKNTTAAPLGLVSPYVSAQS
HHHHHHHHHHEEEEECCCCCCCCHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]