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The map label for this gene is hutC [H]

Identifier: 197103929

GI number: 197103929

Start: 478657

End: 479376

Strand: Reverse

Name: hutC [H]

Synonym: PHZ_c0463

Alternate gene names: 197103929

Gene position: 479376-478657 (Counterclockwise)

Preceding gene: 197103930

Following gene: 197103925

Centisome position: 12.0

GC content: 75.56

Gene sequence:

>720_bases
ATGAGCCGCCTGGACGCCACCCTGCACCGGCGCATCCGCGCCGACGTGCAGGAGAAGATCCTCTCGGGCGCCTGGCCGCC
GGGGCGCCGAATCCCCGCCGAGCACGAGCTGATGGCCGAGTACGGCTGCTCGCGCATGACGGTGAACAAGGCCCTGGGGC
CCCTCGCCGACGCCGGCCTGATCGTGCGCCGCCGCCGCGCCGGCACGTTCGTCGCGCGGCCGAAGATCCATTCCGCCGTG
CTCGACATCCCCGACATCGCCGCCGAGGTGACCGGGCGCGGCGAGACCTACGGCTACGAGCTGCTGTCGCGGACGGCGCG
CGGCGCGAAGGAGGCCGAGGCCGAAGCCCTGGACCTCGGCCCCGGCGACCCTGTCCTGGCCCTGCGCTGCCTGCACCGGG
CGGCCGGCCGGCCGTTCGCCCTGGAGGAGCGGGTGGTCAACCTGACCGCCGCGCCCGAGGCCCGCCTCGTGGATTTCGCC
GGAACCCCGCCCGGCGGTTGGCTGCTGTCGCACGTGCCCTGGACCGAGGCCGAGCACCGCATCAGCGCCCGGAACGCCGG
CCGGACCGTAGCCAAGGCGCTGGCCATCCCCGCCGGGACCGCCTGCCTGGTGCTCGAGCGCCGCACCTGGCGCGGCGCCG
ACCGGATCACGGACGTGCGGCTGACCTTCCCGGGGGAGGCCTACGACCTGATCGCCCGCTTCACGCCCTCGCGCGGCTGA

Upstream 100 bases:

>100_bases
CCGTCTGGCGCCGCGGCCGGCTGGTGGTGTCGGAGGGGCGGCACGTCTGCCGCGGCGCGATCGAGGCGCGGTACCGCGAG
GTCCTGGCGCGGATCGCCGG

Downstream 100 bases:

>100_bases
GCGCCCTCGCCCGCCAGGGCGACGGCCAGCAGCGGCGCCAGGGCCACGGCGTTGGTGGGATGGGGACAGGAGTCCGTCGA
GACGATCCGCTGCACACCGG

Product: histidine utilization repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSRLDATLHRRIRADVQEKILSGAWPPGRRIPAEHELMAEYGCSRMTVNKALGPLADAGLIVRRRRAGTFVARPKIHSAV
LDIPDIAAEVTGRGETYGYELLSRTARGAKEAEAEALDLGPGDPVLALRCLHRAAGRPFALEERVVNLTAAPEARLVDFA
GTPPGGWLLSHVPWTEAEHRISARNAGRTVAKALAIPAGTACLVLERRTWRGADRITDVRLTFPGEAYDLIARFTPSRG

Sequences:

>Translated_239_residues
MSRLDATLHRRIRADVQEKILSGAWPPGRRIPAEHELMAEYGCSRMTVNKALGPLADAGLIVRRRRAGTFVARPKIHSAV
LDIPDIAAEVTGRGETYGYELLSRTARGAKEAEAEALDLGPGDPVLALRCLHRAAGRPFALEERVVNLTAAPEARLVDFA
GTPPGGWLLSHVPWTEAEHRISARNAGRTVAKALAIPAGTACLVLERRTWRGADRITDVRLTFPGEAYDLIARFTPSRG
>Mature_238_residues
SRLDATLHRRIRADVQEKILSGAWPPGRRIPAEHELMAEYGCSRMTVNKALGPLADAGLIVRRRRAGTFVARPKIHSAVL
DIPDIAAEVTGRGETYGYELLSRTARGAKEAEAEALDLGPGDPVLALRCLHRAAGRPFALEERVVNLTAAPEARLVDFAG
TPPGGWLLSHVPWTEAEHRISARNAGRTVAKALAIPAGTACLVLERRTWRGADRITDVRLTFPGEAYDLIARFTPSRG

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50949 HTH_GNTR ; PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLDATLHRRIRADVQEKILSGAWPPGRRIPAEHELMAEYGCSRMTVNKALGPLADAGL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHCCHHHCHH
IVRRRRAGTFVARPKIHSAVLDIPDIAAEVTGRGETYGYELLSRTARGAKEAEAEALDLG
HHHHHCCCCEEECCCHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCEECCC
PGDPVLALRCLHRAAGRPFALEERVVNLTAAPEARLVDFAGTPPGGWLLSHVPWTEAEHR
CCCHHHHHHHHHHHCCCCEEHHHHHEEEECCCCCEEEEECCCCCCCCEECCCCCCCHHHH
ISARNAGRTVAKALAIPAGTACLVLERRTWRGADRITDVRLTFPGEAYDLIARFTPSRG
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRLDATLHRRIRADVQEKILSGAWPPGRRIPAEHELMAEYGCSRMTVNKALGPLADAGL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEHHHHHCCHHHCHH
IVRRRRAGTFVARPKIHSAVLDIPDIAAEVTGRGETYGYELLSRTARGAKEAEAEALDLG
HHHHHCCCCEEECCCHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCEECCC
PGDPVLALRCLHRAAGRPFALEERVVNLTAAPEARLVDFAGTPPGGWLLSHVPWTEAEHR
CCCHHHHHHHHHHHCCCCEEHHHHHEEEECCCCCEEEEECCCCCCCCEECCCCCCCHHHH
ISARNAGRTVAKALAIPAGTACLVLERRTWRGADRITDVRLTFPGEAYDLIARFTPSRG
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2203753 [H]