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The map label for this gene is atsA [H]

Identifier: 197103886

GI number: 197103886

Start: 426441

End: 428675

Strand: Direct

Name: atsA [H]

Synonym: PHZ_c0420

Alternate gene names: 197103886

Gene position: 426441-428675 (Clockwise)

Preceding gene: 197103885

Following gene: 197103887

Centisome position: 10.67

GC content: 73.02

Gene sequence:

>2235_bases
ATGACGGCGAAGATCGGACGGACCGTGGCGGAGTCCACGCCGGAGTGGCCGCAGGCCCCGCGCCCGCCGAAGGGCGCGCC
GAACATCCTGGTCGTGCTGTTCGACGACGTGGGGTTCTCGGACTTCGGCTGCTACGGCTCGCCGATCCGGACGCCGACGA
TCGACCGGCTGGCGGCCGAGGGGCTGCGCTATTCCGGCTTCCACACCACGGCCATGTGCTCGACGACGCGGGCGGCGCTG
CTGACCGGGCGCAACCACCACTCGGTGGGCGTGGGCTGCCTGGCCAACTTCGATTCCGGCTATCCGGGCTACCGCGGCAA
GATCGCCCGCGAGGCGGGGACCCTGCCCGAGATGCTGCGGCCGCACGGCTACCGCAGCTACATGGTCGGCAAGTGGCACG
TCACCCCGCTGACCGAGACGGGGCCGTCGGGGCCGTTCGACGGCTGGCCGCTGGGCCGCGGCTTCGACCGCTTCTACGGC
TTCATGGACGCCGAGACCGACCAGTATTCGCCCGAGCTGGTGCGGGACAACACGCCCGTCCCCGCGCCGGGGACCTACGA
GAGCGGCTACCACCTGACCGAGGATCTGGTGGACCAGTCGATCCGCTACCTCGCCGACCACGTCGCCGACGCGCCGGACA
CGCCGTGGCTGCTGTGGCTGGCGCCGGGGGCGTGCCACGCCCCGCACCAGGCGCCGGCCGAACTGATCCGCAGCTACGAT
GAGGTCTTCAAGGACGGCTGGGACGTGGAGCGCGAGCGGCGGCTCGCGCGCCAGAAGGCCCTGGGGATCGTGCCCCCCGA
CACCCGGCTGCCGCCGCCCAACGACGGGGTGCGGCCCTGGGACAGCTACGCGCCCGACGAGCAGCGGCTGTTCACCCGCC
TGCAGAGCGCCTTCGCCGCCATGCTGGACCACGCCGACCGGCACCTCGGGCGGCTGGTGGACTTCCTGGAGCGGGCCGGC
CTGCGCGAGGACACCCTGATCCTGGTGCTGTCCGACAACGGCGCGAGCCAGGAGGGCGGGCCGCAGGGCTTCGTCAACGC
CATGGGGCCGTTCAACTTCCGCGGCGAGCCGATGGCCGAGAAGATCGCCCGGATCGACGACATCGGCGGGCCCGACACCC
ACTCGAACTTCCCGCAAGGCTGGGCGATGGCGTCGAATACGCCGCTGAAGCGCTACAAGCAGAACACCCACGGCGGCGGC
ATCCGCGACCCGCTGGTGGTCTCATGGCCGAAGCGGATCCCGGCGCGCGGCGAGGTGCGCGAGCGCTTCGCCCACGCCTG
CGACCTGGTCCCCACGCTGCTGGACCTGATCGGGATCGAACCGCCGCAGACGGTGCAGGGCGTGGCCCAGGCGCCGCTGG
AGGGCGAGAGCTTCGCCGCCAGCCTGACCGACCCGGCCGCCCCGCCGCGCAAGGCTGCGCAGTACTTCGAGATGTTCGGC
CACCGGGGGCTCTGGCAGGACGGCTGGAAGGCGGTGGCCTTCCACCCGCCGGGGACGCCCTTCGAGGAGGACCGCTGGGA
GCTCTACCGGCTGGACCGGGACTTCTCGGAGACGGAGGACCTGGCGCAGGCCGAGCCCGGGCGGCTGGCGGCGATGGTGG
ACGACTGGTGGCGGATCGCGGAGGCCTGCAAGGTCCTGCCGCTGGACGACCGCTTCGGGCCGAGGTTCGCCGAGAACGCG
GCGCGCTTCCACGGCGCGCGGCGCCGGTTCGTGTTCCACGCCGGCATGGGCCACCTGCCGACCGACGTGGCGCCCGACGT
GCGGGCCCGCACCTATCGGATCGAGGCCGAGGTGCGGCTGCAGGGCGGGGAGGCGGGCGTGCTGATCGCCCACGGCGACG
CCACCAGCGGCTATTCGCTCTACATCCAGGACGGGCGGCTGAAGCACACGCTGAACATCGGCGGCGAGAAGACCACGGCG
GTCTCGGACCGTCCGGTCCCCGCCGGCGCGACCCGGCTGGGGGTGGTCTCGCGCCGCGTGGGCGAGGGGCCCGAGCGGAC
GTTCACCCTGACCATCGACGGCGCGCCGGCGGGCGAGGTCACGGCCACGACCGGCTTCCACACGCTGATCTCGTGGTCGG
GCCTGGACATCGGCCTCGACCGGGGCAGCCCCGTCGCCGACTACGCCGCCCCGTTCGCCTTCACCGGCGCCTTGCGGAAG
GTGACGGTGAGCATGGACGAGGACCAGGCGCTGGACGGCGAGGCCGTGGGCGCGGCGGAGATGGCGCGGCAGTAG

Upstream 100 bases:

>100_bases
CGCCGGGCCTAGCCGAACTAGCGGGCCGAACTATTGGCACGGCCTTTGCCAATATCCCGGCCGGACCCTATGGTCGCCCC
CTGACTGAAGGAGGGCGGCC

Downstream 100 bases:

>100_bases
GGGGGCGAGGCGGCGCGCGAGCGGCGGCTCTGCATCGGGACACGAAGCGCATGAAGGACTCGAAGGGCGCGAAGGGGGCC
TTCTTCGTGAGCTTCGTGGT

Product: arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MTAKIGRTVAESTPEWPQAPRPPKGAPNILVVLFDDVGFSDFGCYGSPIRTPTIDRLAAEGLRYSGFHTTAMCSTTRAAL
LTGRNHHSVGVGCLANFDSGYPGYRGKIAREAGTLPEMLRPHGYRSYMVGKWHVTPLTETGPSGPFDGWPLGRGFDRFYG
FMDAETDQYSPELVRDNTPVPAPGTYESGYHLTEDLVDQSIRYLADHVADAPDTPWLLWLAPGACHAPHQAPAELIRSYD
EVFKDGWDVERERRLARQKALGIVPPDTRLPPPNDGVRPWDSYAPDEQRLFTRLQSAFAAMLDHADRHLGRLVDFLERAG
LREDTLILVLSDNGASQEGGPQGFVNAMGPFNFRGEPMAEKIARIDDIGGPDTHSNFPQGWAMASNTPLKRYKQNTHGGG
IRDPLVVSWPKRIPARGEVRERFAHACDLVPTLLDLIGIEPPQTVQGVAQAPLEGESFAASLTDPAAPPRKAAQYFEMFG
HRGLWQDGWKAVAFHPPGTPFEEDRWELYRLDRDFSETEDLAQAEPGRLAAMVDDWWRIAEACKVLPLDDRFGPRFAENA
ARFHGARRRFVFHAGMGHLPTDVAPDVRARTYRIEAEVRLQGGEAGVLIAHGDATSGYSLYIQDGRLKHTLNIGGEKTTA
VSDRPVPAGATRLGVVSRRVGEGPERTFTLTIDGAPAGEVTATTGFHTLISWSGLDIGLDRGSPVADYAAPFAFTGALRK
VTVSMDEDQALDGEAVGAAEMARQ

Sequences:

>Translated_744_residues
MTAKIGRTVAESTPEWPQAPRPPKGAPNILVVLFDDVGFSDFGCYGSPIRTPTIDRLAAEGLRYSGFHTTAMCSTTRAAL
LTGRNHHSVGVGCLANFDSGYPGYRGKIAREAGTLPEMLRPHGYRSYMVGKWHVTPLTETGPSGPFDGWPLGRGFDRFYG
FMDAETDQYSPELVRDNTPVPAPGTYESGYHLTEDLVDQSIRYLADHVADAPDTPWLLWLAPGACHAPHQAPAELIRSYD
EVFKDGWDVERERRLARQKALGIVPPDTRLPPPNDGVRPWDSYAPDEQRLFTRLQSAFAAMLDHADRHLGRLVDFLERAG
LREDTLILVLSDNGASQEGGPQGFVNAMGPFNFRGEPMAEKIARIDDIGGPDTHSNFPQGWAMASNTPLKRYKQNTHGGG
IRDPLVVSWPKRIPARGEVRERFAHACDLVPTLLDLIGIEPPQTVQGVAQAPLEGESFAASLTDPAAPPRKAAQYFEMFG
HRGLWQDGWKAVAFHPPGTPFEEDRWELYRLDRDFSETEDLAQAEPGRLAAMVDDWWRIAEACKVLPLDDRFGPRFAENA
ARFHGARRRFVFHAGMGHLPTDVAPDVRARTYRIEAEVRLQGGEAGVLIAHGDATSGYSLYIQDGRLKHTLNIGGEKTTA
VSDRPVPAGATRLGVVSRRVGEGPERTFTLTIDGAPAGEVTATTGFHTLISWSGLDIGLDRGSPVADYAAPFAFTGALRK
VTVSMDEDQALDGEAVGAAEMARQ
>Mature_743_residues
TAKIGRTVAESTPEWPQAPRPPKGAPNILVVLFDDVGFSDFGCYGSPIRTPTIDRLAAEGLRYSGFHTTAMCSTTRAALL
TGRNHHSVGVGCLANFDSGYPGYRGKIAREAGTLPEMLRPHGYRSYMVGKWHVTPLTETGPSGPFDGWPLGRGFDRFYGF
MDAETDQYSPELVRDNTPVPAPGTYESGYHLTEDLVDQSIRYLADHVADAPDTPWLLWLAPGACHAPHQAPAELIRSYDE
VFKDGWDVERERRLARQKALGIVPPDTRLPPPNDGVRPWDSYAPDEQRLFTRLQSAFAAMLDHADRHLGRLVDFLERAGL
REDTLILVLSDNGASQEGGPQGFVNAMGPFNFRGEPMAEKIARIDDIGGPDTHSNFPQGWAMASNTPLKRYKQNTHGGGI
RDPLVVSWPKRIPARGEVRERFAHACDLVPTLLDLIGIEPPQTVQGVAQAPLEGESFAASLTDPAAPPRKAAQYFEMFGH
RGLWQDGWKAVAFHPPGTPFEEDRWELYRLDRDFSETEDLAQAEPGRLAAMVDDWWRIAEACKVLPLDDRFGPRFAENAA
RFHGARRRFVFHAGMGHLPTDVAPDVRARTYRIEAEVRLQGGEAGVLIAHGDATSGYSLYIQDGRLKHTLNIGGEKTTAV
SDRPVPAGATRLGVVSRRVGEGPERTFTLTIDGAPAGEVTATTGFHTLISWSGLDIGLDRGSPVADYAAPFAFTGALRKV
TVSMDEDQALDGEAVGAAEMARQ

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=422, Percent_Identity=25.3554502369668, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI38569407, Length=329, Percent_Identity=25.2279635258359, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI38569405, Length=329, Percent_Identity=24.9240121580547, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI146229331, Length=449, Percent_Identity=27.6169265033408, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI146229329, Length=449, Percent_Identity=27.6169265033408, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI6005990, Length=449, Percent_Identity=27.6169265033408, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI146229324, Length=449, Percent_Identity=27.6169265033408, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI59797060, Length=324, Percent_Identity=26.2345679012346, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI31742482, Length=358, Percent_Identity=27.0949720670391, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4503899, Length=228, Percent_Identity=34.6491228070175, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI53831991, Length=464, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI157266309, Length=330, Percent_Identity=26.3636363636364, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI71852586, Length=152, Percent_Identity=36.1842105263158, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI71852584, Length=152, Percent_Identity=36.1842105263158, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI58743319, Length=158, Percent_Identity=34.8101265822785, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI45430057, Length=420, Percent_Identity=25, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI87081924, Length=549, Percent_Identity=24.0437158469945, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1790233, Length=426, Percent_Identity=25.1173708920188, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17559078, Length=258, Percent_Identity=29.4573643410853, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363223, Length=483, Percent_Identity=26.7080745341615, Blast_Score=124, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281366397, Length=429, Percent_Identity=24.4755244755245, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281366395, Length=429, Percent_Identity=24.4755244755245, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666163, Length=429, Percent_Identity=24.4755244755245, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666175, Length=501, Percent_Identity=24.9500998003992, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666109, Length=458, Percent_Identity=25.5458515283843, Blast_Score=93, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 81531; Mature: 81400

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKIGRTVAESTPEWPQAPRPPKGAPNILVVLFDDVGFSDFGCYGSPIRTPTIDRLAAE
CCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHC
GLRYSGFHTTAMCSTTRAALLTGRNHHSVGVGCLANFDSGYPGYRGKIAREAGTLPEMLR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHHC
PHGYRSYMVGKWHVTPLTETGPSGPFDGWPLGRGFDRFYGFMDAETDQYSPELVRDNTPV
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHCCCCCC
PAPGTYESGYHLTEDLVDQSIRYLADHVADAPDTPWLLWLAPGACHAPHQAPAELIRSYD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
EVFKDGWDVERERRLARQKALGIVPPDTRLPPPNDGVRPWDSYAPDEQRLFTRLQSAFAA
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MLDHADRHLGRLVDFLERAGLREDTLILVLSDNGASQEGGPQGFVNAMGPFNFRGEPMAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCHHH
KIARIDDIGGPDTHSNFPQGWAMASNTPLKRYKQNTHGGGIRDPLVVSWPKRIPARGEVR
HHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHH
ERFAHACDLVPTLLDLIGIEPPQTVQGVAQAPLEGESFAASLTDPAAPPRKAAQYFEMFG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHEECCCCCCCCHHHHHHHHHHHC
HRGLWQDGWKAVAFHPPGTPFEEDRWELYRLDRDFSETEDLAQAEPGRLAAMVDDWWRIA
CCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHH
EACKVLPLDDRFGPRFAENAARFHGARRRFVFHAGMGHLPTDVAPDVRARTYRIEAEVRL
HHHEECCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEE
QGGEAGVLIAHGDATSGYSLYIQDGRLKHTLNIGGEKTTAVSDRPVPAGATRLGVVSRRV
ECCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHH
GEGPERTFTLTIDGAPAGEVTATTGFHTLISWSGLDIGLDRGSPVADYAAPFAFTGALRK
CCCCCEEEEEEECCCCCCCCEECCCHHHHEEECCCEEECCCCCCHHHHHCCHHHHCCCEE
VTVSMDEDQALDGEAVGAAEMARQ
EEEECCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure 
TAKIGRTVAESTPEWPQAPRPPKGAPNILVVLFDDVGFSDFGCYGSPIRTPTIDRLAAE
CCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHC
GLRYSGFHTTAMCSTTRAALLTGRNHHSVGVGCLANFDSGYPGYRGKIAREAGTLPEMLR
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHCCCHHHHC
PHGYRSYMVGKWHVTPLTETGPSGPFDGWPLGRGFDRFYGFMDAETDQYSPELVRDNTPV
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHCCCCCC
PAPGTYESGYHLTEDLVDQSIRYLADHVADAPDTPWLLWLAPGACHAPHQAPAELIRSYD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
EVFKDGWDVERERRLARQKALGIVPPDTRLPPPNDGVRPWDSYAPDEQRLFTRLQSAFAA
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MLDHADRHLGRLVDFLERAGLREDTLILVLSDNGASQEGGPQGFVNAMGPFNFRGEPMAE
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCHHH
KIARIDDIGGPDTHSNFPQGWAMASNTPLKRYKQNTHGGGIRDPLVVSWPKRIPARGEVR
HHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHCCCCCCCCCCCEEEECCCCCCCCCHHH
ERFAHACDLVPTLLDLIGIEPPQTVQGVAQAPLEGESFAASLTDPAAPPRKAAQYFEMFG
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHEECCCCCCCCHHHHHHHHHHHC
HRGLWQDGWKAVAFHPPGTPFEEDRWELYRLDRDFSETEDLAQAEPGRLAAMVDDWWRIA
CCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCEEHHHHHHHHHH
EACKVLPLDDRFGPRFAENAARFHGARRRFVFHAGMGHLPTDVAPDVRARTYRIEAEVRL
HHHEECCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEE
QGGEAGVLIAHGDATSGYSLYIQDGRLKHTLNIGGEKTTAVSDRPVPAGATRLGVVSRRV
ECCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCEEECCCCCCCCCCHHHHHHHHHH
GEGPERTFTLTIDGAPAGEVTATTGFHTLISWSGLDIGLDRGSPVADYAAPFAFTGALRK
CCCCCEEEEEEECCCCCCCCEECCCHHHHEEECCCEEECCCCCCHHHHHCCHHHHCCCEE
VTVSMDEDQALDGEAVGAAEMARQ
EEEECCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]