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The map label for this gene is lipN [H]

Identifier: 197103861

GI number: 197103861

Start: 397442

End: 398488

Strand: Reverse

Name: lipN [H]

Synonym: PHZ_c0395

Alternate gene names: 197103861

Gene position: 398488-397442 (Counterclockwise)

Preceding gene: 197103862

Following gene: 197103860

Centisome position: 9.97

GC content: 75.17

Gene sequence:

>1047_bases
ATGCCGCCGGCCGGGGCCCAGCGCCTGATCGCCCGCACCCTCCTGTCCCTGCCCGCCCCCGTGCTGCGGCTGATGTCGGG
CGGCGGGGTCGTCTACAAGGGCGGGCGCACCCTCGACCCGCGGCTCCAGTTCCTGGCGGCGCAGGCGCGCGGCGCCCCGC
CGATGGAGAGCCTCTCGCCCGAGGAAGCCCGCCGGGGCGAGACCCAGGCCATCGCCGCGGTGGCCGGCTCGCCCGAGCCC
GGCGTGACCTGGGAGGACCTCGCCGTCCCCGGCGCCGCCGGAGAGATCCCCGCCCGCGCCTACCGGCCGCAGGGGCAGGA
CCCCGAGGCTCCGCTGATGGTCTGGGCCCACATGGGCGGCGGCGTGATCGGGACGATCGAGACCACCCACGCCTTCTGCA
CCCTGCTGGCGAAGATCGCCCGCGGGCCGGTCCTGTCGGTGGACTATCGTCTCGCGCCCGAGCACCGCTTTCCCGCCGGC
CTCGACGACGTGCTGGCCGCCTACCGCTGGGGCCGGGACAACGCCGGCCGCTTCGGCGCCCCCGCGGGCAAGGCGGCCCT
GGGCGGCGATTCCATGGGCGGGAACTTCACCGCCGCCGCCTGCCAGATGCTGAAGCGGGCGGGCGAGGATCAGCCGGTGC
TGCAGCTCCTCGTCTATCCCTGCACGGACGTGGCGTCGCAGACGGCCTCCATGACCACCTACGCCGACGCCTTCCCGCTC
TCGCGGCCGATGATGGACTGGTTCATGCGCCACTACCTCGGCCCGGGCGACGATCCGGCCGACCCGCGCCTGTCGCCGCT
GAAGGAGAAGAGCCTCAAGGGCCTGGCGCCGGCGGTCGTGGTCACCGCCGGCTTCGACCCGCTGGTGGACCAGGGCGAGG
CCTACGCCAAGCGGCTGCGCGATGCGGGCGTCCCCACCGCCTACCGCTGCTACGACAGCCTGGCCCACGCCTTCACCGCC
TTCACCGGCGCCGTGCCGGCCGCCGACATCGCCTGCCGCGAGATCGCCGGCCTGGTGCGCGAGGCCTACGAAGGCCGCCT
CGCCTGA

Upstream 100 bases:

>100_bases
GATGATCGAGCGCCGCCCCATCGACACCCAGGCCGCCACCGACTTCGCCGTGGCCATGATCCTCAACGGCCTGCGCGGCC
TGCCGGGGGCGAAGTAGGAG

Downstream 100 bases:

>100_bases
TGCGGGCCCTCGTCGTCGAGCGGCTCGCGCCGGACTACCAGGGCTGTGTCGTCAAGGAGGTCCCGGTCCCCGAGCCCGGT
CCCGGCGAGGTGCGCGTGCG

Product: probable lipase/esterase LipN

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPPAGAQRLIARTLLSLPAPVLRLMSGGGVVYKGGRTLDPRLQFLAAQARGAPPMESLSPEEARRGETQAIAAVAGSPEP
GVTWEDLAVPGAAGEIPARAYRPQGQDPEAPLMVWAHMGGGVIGTIETTHAFCTLLAKIARGPVLSVDYRLAPEHRFPAG
LDDVLAAYRWGRDNAGRFGAPAGKAALGGDSMGGNFTAAACQMLKRAGEDQPVLQLLVYPCTDVASQTASMTTYADAFPL
SRPMMDWFMRHYLGPGDDPADPRLSPLKEKSLKGLAPAVVVTAGFDPLVDQGEAYAKRLRDAGVPTAYRCYDSLAHAFTA
FTGAVPAADIACREIAGLVREAYEGRLA

Sequences:

>Translated_348_residues
MPPAGAQRLIARTLLSLPAPVLRLMSGGGVVYKGGRTLDPRLQFLAAQARGAPPMESLSPEEARRGETQAIAAVAGSPEP
GVTWEDLAVPGAAGEIPARAYRPQGQDPEAPLMVWAHMGGGVIGTIETTHAFCTLLAKIARGPVLSVDYRLAPEHRFPAG
LDDVLAAYRWGRDNAGRFGAPAGKAALGGDSMGGNFTAAACQMLKRAGEDQPVLQLLVYPCTDVASQTASMTTYADAFPL
SRPMMDWFMRHYLGPGDDPADPRLSPLKEKSLKGLAPAVVVTAGFDPLVDQGEAYAKRLRDAGVPTAYRCYDSLAHAFTA
FTGAVPAADIACREIAGLVREAYEGRLA
>Mature_347_residues
PPAGAQRLIARTLLSLPAPVLRLMSGGGVVYKGGRTLDPRLQFLAAQARGAPPMESLSPEEARRGETQAIAAVAGSPEPG
VTWEDLAVPGAAGEIPARAYRPQGQDPEAPLMVWAHMGGGVIGTIETTHAFCTLLAKIARGPVLSVDYRLAPEHRFPAGL
DDVLAAYRWGRDNAGRFGAPAGKAALGGDSMGGNFTAAACQMLKRAGEDQPVLQLLVYPCTDVASQTASMTTYADAFPLS
RPMMDWFMRHYLGPGDDPADPRLSPLKEKSLKGLAPAVVVTAGFDPLVDQGEAYAKRLRDAGVPTAYRCYDSLAHAFTAF
TGAVPAADIACREIAGLVREAYEGRLA

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI157041239, Length=302, Percent_Identity=25.1655629139073, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786682, Length=263, Percent_Identity=24.3346007604563, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567059, Length=261, Percent_Identity=29.8850574712644, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 36695; Mature: 36564

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAGAQRLIARTLLSLPAPVLRLMSGGGVVYKGGRTLDPRLQFLAAQARGAPPMESLSP
CCCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCH
EEARRGETQAIAAVAGSPEPGVTWEDLAVPGAAGEIPARAYRPQGQDPEAPLMVWAHMGG
HHHHCCCHHEEEEECCCCCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCC
GVIGTIETTHAFCTLLAKIARGPVLSVDYRLAPEHRFPAGLDDVLAAYRWGRDNAGRFGA
CEEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCC
PAGKAALGGDSMGGNFTAAACQMLKRAGEDQPVLQLLVYPCTDVASQTASMTTYADAFPL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRPMMDWFMRHYLGPGDDPADPRLSPLKEKSLKGLAPAVVVTAGFDPLVDQGEAYAKRLR
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHCCHHHHHHHHH
DAGVPTAYRCYDSLAHAFTAFTGAVPAADIACREIAGLVREAYEGRLA
HCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPAGAQRLIARTLLSLPAPVLRLMSGGGVVYKGGRTLDPRLQFLAAQARGAPPMESLSP
CCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCH
EEARRGETQAIAAVAGSPEPGVTWEDLAVPGAAGEIPARAYRPQGQDPEAPLMVWAHMGG
HHHHCCCHHEEEEECCCCCCCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCEEEEEECCC
GVIGTIETTHAFCTLLAKIARGPVLSVDYRLAPEHRFPAGLDDVLAAYRWGRDNAGRFGA
CEEEEHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCC
PAGKAALGGDSMGGNFTAAACQMLKRAGEDQPVLQLLVYPCTDVASQTASMTTYADAFPL
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRPMMDWFMRHYLGPGDDPADPRLSPLKEKSLKGLAPAVVVTAGFDPLVDQGEAYAKRLR
CHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHCCHHHHHHHHH
DAGVPTAYRCYDSLAHAFTAFTGAVPAADIACREIAGLVREAYEGRLA
HCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]