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The map label for this gene is can [H]

Identifier: 197103781

GI number: 197103781

Start: 306973

End: 307587

Strand: Direct

Name: can [H]

Synonym: PHZ_c0315

Alternate gene names: 197103781

Gene position: 306973-307587 (Clockwise)

Preceding gene: 197103780

Following gene: 197103782

Centisome position: 7.68

GC content: 69.76

Gene sequence:

>615_bases
ATGCTCGACGAACTCAAGGAAAACAACCGCAACTGGGCCCAGGGGAAGGTCGCCGTCGACCCCGGCTTCTTCAAGCGCCT
CGAGGGCCAGCAGGCGCCCGAGTACCTGTGGATCGGCTGCGCCGACAGCCGGGTGCCGGCCAACGAGATCGTCGGCCTCG
ACCCGGGCGAGCTGTTCGTCCACCGCAACGTGGCCAACCTGGCCCCGCCGCAGGACGCCAACTACCTCAGCGTGCTCCAG
TTCGCCGTCGACGTGCTGAAGGTGAAGCACATCATGGTGGTCGGCCACTACGGCTGCGGCGGCGTCGCCGCGGCGGTGGA
CGGCCAGCGCCGCGGCCTGGTCGACCACTGGCTGCACCCGATCCGCGAGGTCCACCGCGAGCACCGCTGCGAGCTCGAGG
CGATCGGCGACGACCGCGCCCGCTGGGACCGGCTGGTCGAGCTGAACGTGATCCGCCAGGTGCGCAACGTGGCCTCGGAC
GTCTTCGTGCGCGAGGCCTGGAAGCGCGGCCAGCCCCTGTGCGTCCACGGCTGGGTCTATTCGCTGTCCAACGGACTTGT
GAACGACTTGAACGTCACGGTGTCGGGCCCCGAGGAGGCCGAGCGCCTGGCCTGA

Upstream 100 bases:

>100_bases
ACATGGAGCCTTGGCCCGCGATCCGCGCTGTGGCCGAGGCGGCCGCCGTTCACCCGGCCTTCGCCGCCGCCCGACCCGAA
CGCCAACCGGACGCCGCCTG

Downstream 100 bases:

>100_bases
GCTCCGCCGCGCGCTTGACGGGCGGGGCGGGGGCGGCTTGTGTCGCCCCCAACGGCGGGAACGCCGATGAAAACGCTCAG
GAACCGTCCATGAAATCCAT

Product: carbonic anhydrase family protein

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLDELKENNRNWAQGKVAVDPGFFKRLEGQQAPEYLWIGCADSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAVDGQRRGLVDHWLHPIREVHREHRCELEAIGDDRARWDRLVELNVIRQVRNVASD
VFVREAWKRGQPLCVHGWVYSLSNGLVNDLNVTVSGPEEAERLA

Sequences:

>Translated_204_residues
MLDELKENNRNWAQGKVAVDPGFFKRLEGQQAPEYLWIGCADSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAVDGQRRGLVDHWLHPIREVHREHRCELEAIGDDRARWDRLVELNVIRQVRNVASD
VFVREAWKRGQPLCVHGWVYSLSNGLVNDLNVTVSGPEEAERLA
>Mature_204_residues
MLDELKENNRNWAQGKVAVDPGFFKRLEGQQAPEYLWIGCADSRVPANEIVGLDPGELFVHRNVANLAPPQDANYLSVLQ
FAVDVLKVKHIMVVGHYGCGGVAAAVDGQRRGLVDHWLHPIREVHREHRCELEAIGDDRARWDRLVELNVIRQVRNVASD
VFVREAWKRGQPLCVHGWVYSLSNGLVNDLNVTVSGPEEAERLA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=50.7462686567164, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI1786534, Length=172, Percent_Identity=31.9767441860465, Blast_Score=91, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=29.6482412060301, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22913; Mature: 22913

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDELKENNRNWAQGKVAVDPGFFKRLEGQQAPEYLWIGCADSRVPANEIVGLDPGELFV
CCCCHHHCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEECCCCCCCHHHEECCCCHHEEE
HRNVANLAPPQDANYLSVLQFAVDVLKVKHIMVVGHYGCGGVAAAVDGQRRGLVDHWLHP
ECCHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHEECCCCCCCCHHHHHHH
IREVHREHRCELEAIGDDRARWDRLVELNVIRQVRNVASDVFVREAWKRGQPLCVHGWVY
HHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
SLSNGLVNDLNVTVSGPEEAERLA
HHCCCCCCCCEEEECCHHHHHHCC
>Mature Secondary Structure
MLDELKENNRNWAQGKVAVDPGFFKRLEGQQAPEYLWIGCADSRVPANEIVGLDPGELFV
CCCCHHHCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEECCCCCCCHHHEECCCCHHEEE
HRNVANLAPPQDANYLSVLQFAVDVLKVKHIMVVGHYGCGGVAAAVDGQRRGLVDHWLHP
ECCHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHEECCCCCCCCHHHHHHH
IREVHREHRCELEAIGDDRARWDRLVELNVIRQVRNVASDVFVREAWKRGQPLCVHGWVY
HHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHH
SLSNGLVNDLNVTVSGPEEAERLA
HHCCCCCCCCEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]