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The map label for this gene is ycgM [H]

Identifier: 197103779

GI number: 197103779

Start: 305655

End: 306335

Strand: Direct

Name: ycgM [H]

Synonym: PHZ_c0313

Alternate gene names: 197103779

Gene position: 305655-306335 (Clockwise)

Preceding gene: 197103777

Following gene: 197103780

Centisome position: 7.65

GC content: 74.16

Gene sequence:

>681_bases
ATGGCCGAGTTCGCGATCGCACCCGCCCCCGTCCCCACGGTCCCGGTCGAAGGGGAGGCGGCGGCGTTCCCGGTCCGGCG
GATCCTCTGCGTGGGCCAGAACTACGCCGCGCACCGGGCCGAGATGGGCGGCGACGACCGCAACCCGCCGTTCTTCTTCT
CCAAGCCCGCCGACGCCGTGGTCCCGCCCGGTGGCGATCCGGCCTATCCGCCGGCCACGTCCAACCTGCACCACGAGATC
GAGCTGGTGGCCGCCATCGGCAAGGCGGGCCGCGACGTCAGCCCCGCCCAGGCCCTGGATCTCGTCTTCGGCTACGCCGT
CGGCGTCGACCTGACCCGCCGCGACCTGCAGGCCGCCGCCAAGGGCAAGGGCCAGCCCTGGGACAGCGCCAAGGGCTTCG
ACCAGTCGGCCCCGGTCTCGGCGATCCGCCGCTGGACCGGCGCCCCGCCGCAGGGCCGCATCCGCCTCTCGGTCAACGGC
GAGACCCGGCAAGACGCCACGGTCGCCGACATGATCTGGAACGTCGCCGAGATCGTCTCCGAGGCCTCCAAGCTCTGGGC
CCTGGCGCCCGGCGACCTGATCTTCACCGGCACGCCCGAGGGCGTCGGCCCGCTGGTCCGCGGCGACGGGGTCGAGGGCG
AGGTCGACGGCGTCGGCGCCCTGCAGTTCCGGGTGGTCTGA

Upstream 100 bases:

>100_bases
GTTTCGCTCATGGTTCCGCCATACCGCCGCCGGAGGCCCTGCGCGAGACTAACCTTACGTAGGGTTCCCTTCGCCGCGCG
GGGGGCCTAAATGCGCGGCC

Downstream 100 bases:

>100_bases
TGGCGCTCTCGCTGCACAGCTACTGGCGGGCCGGGGCGCCCTACCGGGTCCGCATCGGCCTGAACCTGAAGGGCCTGTCC
TACGACTACGTCCCGGTGAA

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAEFAIAPAPVPTVPVEGEAAAFPVRRILCVGQNYAAHRAEMGGDDRNPPFFFSKPADAVVPPGGDPAYPPATSNLHHEI
ELVAAIGKAGRDVSPAQALDLVFGYAVGVDLTRRDLQAAAKGKGQPWDSAKGFDQSAPVSAIRRWTGAPPQGRIRLSVNG
ETRQDATVADMIWNVAEIVSEASKLWALAPGDLIFTGTPEGVGPLVRGDGVEGEVDGVGALQFRVV

Sequences:

>Translated_226_residues
MAEFAIAPAPVPTVPVEGEAAAFPVRRILCVGQNYAAHRAEMGGDDRNPPFFFSKPADAVVPPGGDPAYPPATSNLHHEI
ELVAAIGKAGRDVSPAQALDLVFGYAVGVDLTRRDLQAAAKGKGQPWDSAKGFDQSAPVSAIRRWTGAPPQGRIRLSVNG
ETRQDATVADMIWNVAEIVSEASKLWALAPGDLIFTGTPEGVGPLVRGDGVEGEVDGVGALQFRVV
>Mature_225_residues
AEFAIAPAPVPTVPVEGEAAAFPVRRILCVGQNYAAHRAEMGGDDRNPPFFFSKPADAVVPPGGDPAYPPATSNLHHEIE
LVAAIGKAGRDVSPAQALDLVFGYAVGVDLTRRDLQAAAKGKGQPWDSAKGFDQSAPVSAIRRWTGAPPQGRIRLSVNGE
TRQDATVADMIWNVAEIVSEASKLWALAPGDLIFTGTPEGVGPLVRGDGVEGEVDGVGALQFRVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=42.5742574257426, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI66348062, Length=195, Percent_Identity=43.0769230769231, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI215422413, Length=195, Percent_Identity=43.0769230769231, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI156231349, Length=231, Percent_Identity=31.6017316017316, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI40786394, Length=210, Percent_Identity=30.952380952381, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI1787428, Length=213, Percent_Identity=40.3755868544601, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=34.0425531914894, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=238, Percent_Identity=34.0336134453782, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28572127, Length=240, Percent_Identity=32.9166666666667, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI28571789, Length=179, Percent_Identity=35.7541899441341, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24663695, Length=207, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23656; Mature: 23525

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFAIAPAPVPTVPVEGEAAAFPVRRILCVGQNYAAHRAEMGGDDRNPPFFFSKPADAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCCCC
VPPGGDPAYPPATSNLHHEIELVAAIGKAGRDVSPAQALDLVFGYAVGVDLTRRDLQAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
KGKGQPWDSAKGFDQSAPVSAIRRWTGAPPQGRIRLSVNGETRQDATVADMIWNVAEIVS
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
EASKLWALAPGDLIFTGTPEGVGPLVRGDGVEGEVDGVGALQFRVV
HHHHEEEECCCCEEEECCCCCCCCCEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
AEFAIAPAPVPTVPVEGEAAAFPVRRILCVGQNYAAHRAEMGGDDRNPPFFFSKPADAV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCEEEECCCCCC
VPPGGDPAYPPATSNLHHEIELVAAIGKAGRDVSPAQALDLVFGYAVGVDLTRRDLQAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
KGKGQPWDSAKGFDQSAPVSAIRRWTGAPPQGRIRLSVNGETRQDATVADMIWNVAEIVS
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
EASKLWALAPGDLIFTGTPEGVGPLVRGDGVEGEVDGVGALQFRVV
HHHHEEEECCCCEEEECCCCCCCCCEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]