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The map label for this gene is moaE [H]

Identifier: 197103744

GI number: 197103744

Start: 273462

End: 273917

Strand: Reverse

Name: moaE [H]

Synonym: PHZ_c0278

Alternate gene names: 197103744

Gene position: 273917-273462 (Counterclockwise)

Preceding gene: 197103745

Following gene: 197103743

Centisome position: 6.85

GC content: 71.93

Gene sequence:

>456_bases
ATGATCCGGCTGACCGACCAGCCCTTCGACCCCGGCGCCCTGCTCGGCGAGTTCAGCCGCGCGCGCACCGAGACCGGCGC
GGTGGCCACCTTCACCGGCATCGCGCGGGCCGAGCAGGGCTCCACCGCCGTTCTGGAGCTGGAGGCCTATCCCGGCTTCA
CCGAAGCGCACATCGGCAAGATCGCCGAGGAGGCGAAGCGGCGCTTCGGGCTCCACGACCTCGCCATCCTGCACCGGGTG
GGCAGGATCGCTCCGGGCGAGCCGATCGTCTTCGTCGCCACGGCGGCCGGCCACCGCCGGGCCGCCTTCGAGGCCTGCGA
CTTCCTGATGGACTACTTGAAGTCCAAGGCGCCGTTCTGGAAGAAGGAGCACGGCCCCGGCGGCGCCCGCTGGATCGAGC
CCACCGCCCAGGACCACGCCGACCGCGCCCGCTGGGAAAAGGAGACCCCGCCATGA

Upstream 100 bases:

>100_bases
CCCCCGGCGTGCAGGTGGCCCTCGACCAGGCGCTGGTGCGCGGCGATCCGGCCCTGGCGGCGGGGTCCGAGGTCGCCTTC
CTGCCGCCGATGAGCGGCGG

Downstream 100 bases:

>100_bases
ACGCCTTCACCCCCGGCGGCCGCATCGACGAGACCCGGCCCTTCAAGCCCGTGCGCATCGCCGTGCTGACCATCTCGGAC
ACCCGCGACGAGGAGAGCGA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MIRLTDQPFDPGALLGEFSRARTETGAVATFTGIARAEQGSTAVLELEAYPGFTEAHIGKIAEEAKRRFGLHDLAILHRV
GRIAPGEPIVFVATAAGHRRAAFEACDFLMDYLKSKAPFWKKEHGPGGARWIEPTAQDHADRARWEKETPP

Sequences:

>Translated_151_residues
MIRLTDQPFDPGALLGEFSRARTETGAVATFTGIARAEQGSTAVLELEAYPGFTEAHIGKIAEEAKRRFGLHDLAILHRV
GRIAPGEPIVFVATAAGHRRAAFEACDFLMDYLKSKAPFWKKEHGPGGARWIEPTAQDHADRARWEKETPP
>Mature_151_residues
MIRLTDQPFDPGALLGEFSRARTETGAVATFTGIARAEQGSTAVLELEAYPGFTEAHIGKIAEEAKRRFGLHDLAILHRV
GRIAPGEPIVFVATAAGHRRAAFEACDFLMDYLKSKAPFWKKEHGPGGARWIEPTAQDHADRARWEKETPP

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=109, Percent_Identity=32.1100917431193, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1787003, Length=141, Percent_Identity=44.6808510638298, Blast_Score=122, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16622; Mature: 16622

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLTDQPFDPGALLGEFSRARTETGAVATFTGIARAEQGSTAVLELEAYPGFTEAHIGK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
IAEEAKRRFGLHDLAILHRVGRIAPGEPIVFVATAAGHRRAAFEACDFLMDYLKSKAPFW
HHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
KKEHGPGGARWIEPTAQDHADRARWEKETPP
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRLTDQPFDPGALLGEFSRARTETGAVATFTGIARAEQGSTAVLELEAYPGFTEAHIGK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHH
IAEEAKRRFGLHDLAILHRVGRIAPGEPIVFVATAAGHRRAAFEACDFLMDYLKSKAPFW
HHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
KKEHGPGGARWIEPTAQDHADRARWEKETPP
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]