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The map label for this gene is sugE [H]

Identifier: 197103706

GI number: 197103706

Start: 243195

End: 243521

Strand: Direct

Name: sugE [H]

Synonym: PHZ_c0240

Alternate gene names: 197103706

Gene position: 243195-243521 (Clockwise)

Preceding gene: 197103705

Following gene: 197103715

Centisome position: 6.09

GC content: 69.42

Gene sequence:

>327_bases
ATGGCCTGGGTCATCCTGTTCGTCGCCGGCCTGTTCGAAGTCGCCTGGGCCGTGGGGCTCAAGTACACCGAGGGCTTCAC
CCGGATCGGCCCCACGATCTTCACCGCCGTCAGCCTGGCCGCCAGCATGGGCCTCCTCGGCATGGCGGTCCGCAGCCTGC
CGCTCGGCACGGCCTACGCCATCTGGACCGGCATCGGGGCCCTGGGCACCGTCATCCTCGGCATCGTGCTGTTCAAGGAG
CCGGCCACGGTCGCGCGGCTGTTCTGCGTGGGCCTGATCCTGGCCGGCATCGTCGGACTGAAGCTGGTGACCAAGGACGC
GGGCTAG

Upstream 100 bases:

>100_bases
CAGGAACGCAAGTTCTAAGAGCTGCCCGCGCGCCGGGGACGACCCCGGCGCGTCTCCTTTCCCGGGAGGACGACCTCCGT
CGCAAGAAGGAGGCCAGCCC

Downstream 100 bases:

>100_bases
GGCCCGTCCCAGGCCTCTAGGCGGCGGCGCGGGCCTGCCCCTCCAGCCAGTCCAGCGCCAGGTCCGCCACCGCCTCCCAG
CCCGGCTCGGCGGGCAGCCA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MAWVILFVAGLFEVAWAVGLKYTEGFTRIGPTIFTAVSLAASMGLLGMAVRSLPLGTAYAIWTGIGALGTVILGIVLFKE
PATVARLFCVGLILAGIVGLKLVTKDAG

Sequences:

>Translated_108_residues
MAWVILFVAGLFEVAWAVGLKYTEGFTRIGPTIFTAVSLAASMGLLGMAVRSLPLGTAYAIWTGIGALGTVILGIVLFKE
PATVARLFCVGLILAGIVGLKLVTKDAG
>Mature_107_residues
AWVILFVAGLFEVAWAVGLKYTEGFTRIGPTIFTAVSLAASMGLLGMAVRSLPLGTAYAIWTGIGALGTVILGIVLFKEP
ATVARLFCVGLILAGIVGLKLVTKDAG

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=105, Percent_Identity=57.1428571428571, Blast_Score=119, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11170; Mature: 11038

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVILFVAGLFEVAWAVGLKYTEGFTRIGPTIFTAVSLAASMGLLGMAVRSLPLGTAYA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGALGTVILGIVLFKEPATVARLFCVGLILAGIVGLKLVTKDAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AWVILFVAGLFEVAWAVGLKYTEGFTRIGPTIFTAVSLAASMGLLGMAVRSLPLGTAYA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGALGTVILGIVLFKEPATVARLFCVGLILAGIVGLKLVTKDAG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]