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The map label for this gene is pyrF [H]

Identifier: 197103519

GI number: 197103519

Start: 44024

End: 44689

Strand: Direct

Name: pyrF [H]

Synonym: PHZ_c0053

Alternate gene names: 197103519

Gene position: 44024-44689 (Clockwise)

Preceding gene: 197103517

Following gene: 197103520

Centisome position: 1.1

GC content: 75.53

Gene sequence:

>666_bases
GTGCCGCTGGACCTGCCGACCGTGGCCGAGGCGCGGGCCATGGTCGCGCGGCTGGGCGAGGCGGTCGGCTTCTACAAGGT
GGGGCTGGAGCTGTTCGCCAGCGACGGCATGGCGCTGGCCCGCGAGCTGAAGGGCCAGGGCAAGCAGGTGTTCCTCGACT
GGAAGCTGCACGACATCGGCACCACCGTGCAGCGCGCCGCCGCGGTGCTGGCGGGCCAGGGCTGCGACTTCCTCACCGTC
CACGGCGAACCGCAGGTGATGGCCGCCGCGGTCCGCGGCCGCGGGGACTCGGACCTGAAGGTGCTGGCGGTGACCGTGCT
CACCAGCCTCACCGACGCCGACCTGAGGGAGATGGGCTTCACCGAGACCGCCCGCGAGCTGGTCGAGCGCCGCATCCGCC
AGGCGATCGCCGCCGGCTGCGACGGGGTGATCGCCAGCCCGCACGAGGCCGAGCTGGCCCGCGCCCTGGGCGGCAAGGAC
TTCCTCGTCGTCACGCCGGGCGTGCGGCCCGAGTGGGCGGCGAAGAACGACCAGGCCCGGGCGGCGACGCCGGCTGACGC
GCTGCGCGCCGGCGCCTCGCACATCGTCTGCGGCCGCCCGATCACCGGGGCCGAGGACCCCCTGGCCGCGGCGCGGCGCA
TCGCCGCCGAGATGGCGGGCCTGTAG

Upstream 100 bases:

>100_bases
TGAATCCAACCCCGCGGACCACCCGCCTCTCCGGAGCCATGCCATGGCCGCCGCCGCCGCCGCTGCGCAAACCGCCCCCG
CCGCCGATCCGCGCCTGATC

Downstream 100 bases:

>100_bases
TCCCTTCGGGAACCCACGGCCAAGCTGGGCGTCTAGGCTTGCAGCCTGGACCCGCCATGACCGACCCACGAATGAAACCG
CTGGCCCTGCGCCGCCTGAC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MPLDLPTVAEARAMVARLGEAVGFYKVGLELFASDGMALARELKGQGKQVFLDWKLHDIGTTVQRAAAVLAGQGCDFLTV
HGEPQVMAAAVRGRGDSDLKVLAVTVLTSLTDADLREMGFTETARELVERRIRQAIAAGCDGVIASPHEAELARALGGKD
FLVVTPGVRPEWAAKNDQARAATPADALRAGASHIVCGRPITGAEDPLAAARRIAAEMAGL

Sequences:

>Translated_221_residues
MPLDLPTVAEARAMVARLGEAVGFYKVGLELFASDGMALARELKGQGKQVFLDWKLHDIGTTVQRAAAVLAGQGCDFLTV
HGEPQVMAAAVRGRGDSDLKVLAVTVLTSLTDADLREMGFTETARELVERRIRQAIAAGCDGVIASPHEAELARALGGKD
FLVVTPGVRPEWAAKNDQARAATPADALRAGASHIVCGRPITGAEDPLAAARRIAAEMAGL
>Mature_220_residues
PLDLPTVAEARAMVARLGEAVGFYKVGLELFASDGMALARELKGQGKQVFLDWKLHDIGTTVQRAAAVLAGQGCDFLTVH
GEPQVMAAAVRGRGDSDLKVLAVTVLTSLTDADLREMGFTETARELVERRIRQAIAAGCDGVIASPHEAELARALGGKDF
LVVTPGVRPEWAAKNDQARAATPADALRAGASHIVCGRPITGAEDPLAAARRIAAEMAGL

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=222, Percent_Identity=36.9369369369369, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 23191; Mature: 23060

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLDLPTVAEARAMVARLGEAVGFYKVGLELFASDGMALARELKGQGKQVFLDWKLHDIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEHHHHH
TTVQRAAAVLAGQGCDFLTVHGEPQVMAAAVRGRGDSDLKVLAVTVLTSLTDADLREMGF
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TETARELVERRIRQAIAAGCDGVIASPHEAELARALGGKDFLVVTPGVRPEWAAKNDQAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCC
AATPADALRAGASHIVCGRPITGAEDPLAAARRIAAEMAGL
CCCCHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLDLPTVAEARAMVARLGEAVGFYKVGLELFASDGMALARELKGQGKQVFLDWKLHDIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEHHHHH
TTVQRAAAVLAGQGCDFLTVHGEPQVMAAAVRGRGDSDLKVLAVTVLTSLTDADLREMGF
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
TETARELVERRIRQAIAAGCDGVIASPHEAELARALGGKDFLVVTPGVRPEWAAKNDQAR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCC
AATPADALRAGASHIVCGRPITGAEDPLAAARRIAAEMAGL
CCCCHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA