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The map label for this gene is argG [H]

Identifier: 197103514

GI number: 197103514

Start: 38611

End: 39885

Strand: Reverse

Name: argG [H]

Synonym: PHZ_c0048

Alternate gene names: 197103514

Gene position: 39885-38611 (Counterclockwise)

Preceding gene: 197103515

Following gene: 197103512

Centisome position: 1.0

GC content: 67.61

Gene sequence:

>1275_bases
ATGGCCGACAAGAAGCCCGTCAAGAAGGTCGTGCTCGCCTACTCCGGCGGCCTCGACACCTCGATCATCCTGAAGTGGCT
GCAGACCGAGTACCGCGCCGAGGTGGTCACCTTCACCGCCGACCTCGGCCAGGGCGAGGAGCTGACCCCCGCCCGCGAGA
AGGCGCTGATGCTGGGCATCAAGCCCGAGAACATCTTCATCGACGACCTGCGCGAGGAGTTCGTCCGGGACTTCGTCTTC
CCGATGTTCCGCGCCAACACCGTCTACGAGGGCCAGTACCTGCTCGGCACCTCGATCGCCCGGCCGCTGATCGCCAAGCG
CCAGATCGAGATCGCCCGCCAGGTTGGCGCCGACGCCGTCTGCCACGGCGCCACGGGCAAGGGGAACGACCAGGTCCGCT
TCGAGCTGGGCTACTACGCCCTCGAGCCCGACATCCGGGTGATCGCCCCCTGGCGCGAATGGGACTTCCGCAGCCGCGAG
GCCCTGATCGACTTCGCCGAGAAGCACCAGATCCCGATCAGCAAGGACAAGCGCGGCGAGGCGCCGTTCAGCGTGGACGC
CAACCTGCTGCACTCCTCCTCGGAAGGTAAGGTGCTGGAAGACCCTTCGGTCGAGGCCCCCGAGTTCGTGCACATGCGCA
CGATCGCCCCCGAGGACGCGCCCGACAAGGCGACCGTCATCACCATCGACTTCGAGAAGGGCGACCCCGTCGCCATCGAC
GGCCAGAAGCTGTCGCCCGCCGCCCTGCTGGCGAGGCTGAACGAGCTCGGCCACGACAATGGGATCGGCCGCCTCGACCT
GGTGGAGAATCGCTTCGTCGGCATGAAGTCGCGCGGCGTCTACGAGACGCCCGGCGGGACCATCCTGCTCGCCGCCCACC
GCGGCATCGAGAGCATCACCCTCGACCGGGGCGCCATGCACCTGAAGGACGAGCTGATGCCGAAGTACGCCGGCCTGATC
TACAACGGCTTCTGGTTCTCGGCCGAGCGCGAGATGCTGCAGGCGGCCATCGACAAGAGCCAGGAGCCGGTGGCCGGCCA
GGTGCGGGTCAAGCTCTACAAGGGCAATGTCACGGTCATCGGCCGCACCAGCCCCTACTCGCTCTACGACCAGGAGCTGG
TGACCTTCGAGGAAGGCGCGGTCGCCTACGACCACCGCGACGCCGAGGGCTTCATCAAGCTGAACGCCCTGCGCCTGCGG
GTCATGGCCAATCGCGACCGCCGCCGGGGCAAGCCGCTGGCGGAGATCCCCGACGGCGAACACTTCACGGGCTAG

Upstream 100 bases:

>100_bases
GGAGGACGAAGGCGCACTCAGGCCTTGAACCGCAGAGCCGCGTGCCCTTAAAGGCGCGCGACCGTTCCTCCGCACCTCAT
TTCGCAAGGTCCCAGCCCCG

Downstream 100 bases:

>100_bases
CCGTCCAGGCGGTTGTAAGGATAGCGGTCGCGGATCTCGGCCTGGAAGAACCGCCCCTTCGACGGGGCGTCCAGGAACGA
GCGGTGCACCTCGCCCGGCA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MADKKPVKKVVLAYSGGLDTSIILKWLQTEYRAEVVTFTADLGQGEELTPAREKALMLGIKPENIFIDDLREEFVRDFVF
PMFRANTVYEGQYLLGTSIARPLIAKRQIEIARQVGADAVCHGATGKGNDQVRFELGYYALEPDIRVIAPWREWDFRSRE
ALIDFAEKHQIPISKDKRGEAPFSVDANLLHSSSEGKVLEDPSVEAPEFVHMRTIAPEDAPDKATVITIDFEKGDPVAID
GQKLSPAALLARLNELGHDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESITLDRGAMHLKDELMPKYAGLI
YNGFWFSAEREMLQAAIDKSQEPVAGQVRVKLYKGNVTVIGRTSPYSLYDQELVTFEEGAVAYDHRDAEGFIKLNALRLR
VMANRDRRRGKPLAEIPDGEHFTG

Sequences:

>Translated_424_residues
MADKKPVKKVVLAYSGGLDTSIILKWLQTEYRAEVVTFTADLGQGEELTPAREKALMLGIKPENIFIDDLREEFVRDFVF
PMFRANTVYEGQYLLGTSIARPLIAKRQIEIARQVGADAVCHGATGKGNDQVRFELGYYALEPDIRVIAPWREWDFRSRE
ALIDFAEKHQIPISKDKRGEAPFSVDANLLHSSSEGKVLEDPSVEAPEFVHMRTIAPEDAPDKATVITIDFEKGDPVAID
GQKLSPAALLARLNELGHDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESITLDRGAMHLKDELMPKYAGLI
YNGFWFSAEREMLQAAIDKSQEPVAGQVRVKLYKGNVTVIGRTSPYSLYDQELVTFEEGAVAYDHRDAEGFIKLNALRLR
VMANRDRRRGKPLAEIPDGEHFTG
>Mature_423_residues
ADKKPVKKVVLAYSGGLDTSIILKWLQTEYRAEVVTFTADLGQGEELTPAREKALMLGIKPENIFIDDLREEFVRDFVFP
MFRANTVYEGQYLLGTSIARPLIAKRQIEIARQVGADAVCHGATGKGNDQVRFELGYYALEPDIRVIAPWREWDFRSREA
LIDFAEKHQIPISKDKRGEAPFSVDANLLHSSSEGKVLEDPSVEAPEFVHMRTIAPEDAPDKATVITIDFEKGDPVAIDG
QKLSPAALLARLNELGHDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESITLDRGAMHLKDELMPKYAGLIY
NGFWFSAEREMLQAAIDKSQEPVAGQVRVKLYKGNVTVIGRTSPYSLYDQELVTFEEGAVAYDHRDAEGFIKLNALRLRV
MANRDRRRGKPLAEIPDGEHFTG

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=400, Percent_Identity=48.25, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI16950633, Length=400, Percent_Identity=48.25, Blast_Score=357, Evalue=1e-98,
Organism=Escherichia coli, GI1789563, Length=417, Percent_Identity=26.378896882494, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324514, Length=421, Percent_Identity=43.4679334916865, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI21358151, Length=408, Percent_Identity=45.0980392156863, Blast_Score=338, Evalue=3e-93,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 47343; Mature: 47211

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKPVKKVVLAYSGGLDTSIILKWLQTEYRAEVVTFTADLGQGEELTPAREKALMLGI
CCCCCCHHHEEEEECCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCHHCCEEEEEC
KPENIFIDDLREEFVRDFVFPMFRANTVYEGQYLLGTSIARPLIAKRQIEIARQVGADAV
CCCCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHHHHHHCCCCCE
CHGATGKGNDQVRFELGYYALEPDIRVIAPWREWDFRSREALIDFAEKHQIPISKDKRGE
EECCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
APFSVDANLLHSSSEGKVLEDPSVEAPEFVHMRTIAPEDAPDKATVITIDFEKGDPVAID
CCCEECHHHEECCCCCCEECCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCEEEC
GQKLSPAALLARLNELGHDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESIT
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEEEECCCCCEEE
LDRGAMHLKDELMPKYAGLIYNGFWFSAEREMLQAAIDKSQEPVAGQVRVKLYKGNVTVI
ECCCCHHHHHHHHHHHHCEEEECEEEHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEEEE
GRTSPYSLYDQELVTFEEGAVAYDHRDAEGFIKLNALRLRVMANRDRRRGKPLAEIPDGE
ECCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEEEEEEEEECCHHHCCCCCCCCCCCC
HFTG
CCCC
>Mature Secondary Structure 
ADKKPVKKVVLAYSGGLDTSIILKWLQTEYRAEVVTFTADLGQGEELTPAREKALMLGI
CCCCCHHHEEEEECCCCCHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCHHCCEEEEEC
KPENIFIDDLREEFVRDFVFPMFRANTVYEGQYLLGTSIARPLIAKRQIEIARQVGADAV
CCCCEEHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHHHHHHCCCCCE
CHGATGKGNDQVRFELGYYALEPDIRVIAPWREWDFRSREALIDFAEKHQIPISKDKRGE
EECCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
APFSVDANLLHSSSEGKVLEDPSVEAPEFVHMRTIAPEDAPDKATVITIDFEKGDPVAID
CCCEECHHHEECCCCCCEECCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCEEEC
GQKLSPAALLARLNELGHDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESIT
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEEEECCCCCEEE
LDRGAMHLKDELMPKYAGLIYNGFWFSAEREMLQAAIDKSQEPVAGQVRVKLYKGNVTVI
ECCCCHHHHHHHHHHHHCEEEECEEEHHHHHHHHHHHCCCCCCCCCEEEEEEEECCEEEE
GRTSPYSLYDQELVTFEEGAVAYDHRDAEGFIKLNALRLRVMANRDRRRGKPLAEIPDGE
ECCCCCCCCCCCEEEEECCCEEECCCCCCCEEEEEEEEEEEEECCHHHCCCCCCCCCCCC
HFTG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA