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The map label for this gene is cspZ.1 [H]

Identifier: 195978898

GI number: 195978898

Start: 1866077

End: 1867450

Strand: Direct

Name: cspZ.1 [H]

Synonym: Sez_1802

Alternate gene names: 195978898

Gene position: 1866077-1867450 (Clockwise)

Preceding gene: 195978897

Following gene: 195978911

Centisome position: 92.19

GC content: 40.68

Gene sequence:

>1374_bases
ATGAATAATAGTTATAAGGAGTTATTAATGAAAAAGAATCAAGTTACCCGATACTCTTTACTTATCCCAGCTGCTTTAAT
GGCTGCTGGTTTAGCGATGTCAACTAACTCGTCAGTAGCATTTGCTGATGAATCACCAGCAGTGGATAATCACACTGTAG
TCCAACCGAGGTTAGGTGAGGATAAAGATACTGCAGATACATCTAATCAACAGTTATCTGACAGCACTGAGGTGATGGCT
GATAAACCAATTACAAAAGCATCAGAAACCGCAAATCCTGTAGCAGCAGCTGATAAATTACCGCTAGACACTAATCAATC
AGCTGAAGATATTATTGCCGTAAAAAAAGCTTATATCGCCAAAAATACAGGCTTGCCATTAGACAAGATTCAATTATTGG
ATACTTCAGAGGGTAAGGCCTTGATGTATCCACATGACGATCATCATCATGTTATTTTATTGGATAAGATTGATGTTTCT
AAGCCTTTTGACGATGGGCACAGTAGTCATCACAGTGATCATGCACACCACCATCATGATGATGTTATTGAAGGTAGCTT
TGCTTTTACCGCAACAGTTATAGACCCTGAGGGTAAAGTATTATCTGGAAAAGACGTCCAAGTGGTAGATATAACAAGTG
GCAGAAAAACACTTGCGACTGTGACAACAGATGAAAAAGGACAAGCTGTTTTTGACAAGCTTCCTTTAGGAAGAAGTTTA
TCAATTTTTGTGAATGGCGTTCCTCAAGGCTATACTGTACGAACAGGTGTTGATGGCGACAAGCATTCAGCTAGCTTTAC
TGTTGACGGAAAAGGAACAGTTGAGCCAGAATACAGTAAAACACCTTTGGTTGTTATCGTTCGTAATGAAGATGCTGAAC
CTTTATCAGGACAAGAAGTCACTCTAAAGCATAGAGTAGGTCGTGTGATAGAGAAAGTAACAACAGGAGCTGATGGCAAA
GCTGTATTTTCTAAAGGGCTTCTAGATGGCACTTTCTATGAGCTTTTTGTCAACGGCAAAAAGCTTTCTCAAGCTACAAC
AGGTGAGGAAAGAAGCGTTGCCCTAGATGCTAAAGATATTAAAAAATCAAGTCCACATTCAAAACCACAAGAAGACGCAC
CTAAAGTTCCAGAAACCAAACCAGAAACTAAGCCAGAGGCTAAACCACTCAGTCCTGAAAAAGCTGATCAAGCAGGTAAA
GTAGCAGCGCCAGCTCACACAGCTTCTAAAGCAGCAGCAGCTAAAGCTGAGATGAAGAAAACGACTAATCAATTGCCAGC
AACAGGTGAGGCTGTGAACCCATTCTTCACCGCAGCTGCACTTGCAGTTATGGCTACAGCTGGTGTAGCAGCTATAAAAC
GTAAGGAAAATTAA

Upstream 100 bases:

>100_bases
GATTTTCTTCATACGTTTGTTCTGATTAAATCACTTTAAGGGGTTGACATACTATATTTTTTTTGATAGATTGATATAGT
TAACTGGTTAATTAATTAAA

Downstream 100 bases:

>100_bases
CAAAAGTCAAACTGAGGTCAAAGGCCTTAGAAATCAAGTCCTTCTCTACCATTTGTCAAGCTGATCAAAGCTTTAGATAA
AAATGATTTTTGAGACAGTA

Product: Emm-like cell surface protein CspZ.1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNNSYKELLMKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTVVQPRLGEDKDTADTSNQQLSDSTEVMA
DKPITKASETANPVAAADKLPLDTNQSAEDIIAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVS
KPFDDGHSSHHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKGQAVFDKLPLGRSL
SIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVVIVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGK
AVFSKGLLDGTFYELFVNGKKLSQATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGK
VAAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN

Sequences:

>Translated_457_residues
MNNSYKELLMKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTVVQPRLGEDKDTADTSNQQLSDSTEVMA
DKPITKASETANPVAAADKLPLDTNQSAEDIIAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVS
KPFDDGHSSHHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKGQAVFDKLPLGRSL
SIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVVIVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGK
AVFSKGLLDGTFYELFVNGKKLSQATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGK
VAAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN
>Mature_457_residues
MNNSYKELLMKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTVVQPRLGEDKDTADTSNQQLSDSTEVMA
DKPITKASETANPVAAADKLPLDTNQSAEDIIAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVS
KPFDDGHSSHHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKGQAVFDKLPLGRSL
SIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVVIVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGK
AVFSKGLLDGTFYELFVNGKKLSQATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGK
VAAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN

Specific function: This protein is one of the different antigenic serotypes of protein M. Protein M is closely associated with virulence of the bacterium and can render the organism resistant to phagocytosis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the M protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019950
- InterPro:   IPR019931
- InterPro:   IPR003345
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00746 Gram_pos_anchor; PF02370 M; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 48701; Mature: 48701

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSYKELLMKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTVVQPRLGE
CCCHHHHHHHHCCCCEEHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEEECCCCCC
DKDTADTSNQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDIIAVKKAYIA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
KNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGHSSHHSDHAHHHHD
CCCCCCHHHEEEEECCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
DVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKGQAVFDKLPLGRSL
CCCCCCEEEEEEEECCCCCEECCCCEEEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEE
SIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVVIVRNEDAEPLSGQEV
EEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEE
TLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYELFVNGKKLSQATTGEERSVALDAKDI
EHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCEEEECHHHH
KKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKVAAPAHTASKAAAAKAEMKK
HCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCHHHHHHHHHHHHHHH
TTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNSYKELLMKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTVVQPRLGE
CCCHHHHHHHHCCCCEEHHHHHHHHHHHCCEEECCCCCEEECCCCCCCCCCEEECCCCCC
DKDTADTSNQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDIIAVKKAYIA
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHH
KNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGHSSHHSDHAHHHHD
CCCCCCHHHEEEEECCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
DVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKGQAVFDKLPLGRSL
CCCCCCEEEEEEEECCCCCEECCCCEEEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEE
SIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVVIVRNEDAEPLSGQEV
EEEEECCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEE
TLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYELFVNGKKLSQATTGEERSVALDAKDI
EHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEEECCCHHHHCCCCCCCEEEECHHHH
KKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKVAAPAHTASKAAAAKAEMKK
HCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCHHHHHHHHHHHHHHH
TTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3281944; 7891551; 6368549 [H]