| Definition | Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome. |
|---|---|
| Accession | NC_011134 |
| Length | 2,024,171 |
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The map label for this gene is ppiB [C]
Identifier: 195978568
GI number: 195978568
Start: 1506648
End: 1507454
Strand: Direct
Name: ppiB [C]
Synonym: Sez_1466
Alternate gene names: 195978568
Gene position: 1506648-1507454 (Clockwise)
Preceding gene: 195978567
Following gene: 195978572
Centisome position: 74.43
GC content: 42.75
Gene sequence:
>807_bases ATGAAAAAACTACTATCTTTTGGCTTAATCGGTCTTGCTTTGCTTAGCTTAAGTGGCTGTGAGTCTATTGATCGTGCTAT TAAAGGTGATGAATATGTCGACGAAAAAATAGCTAGAGAGGAAAGCGAGGCAGCAGCAAAGGCTTATGAAGCAAAAATCA AAAAAGCGCTCAAGGCTGACGCTGATCAGTTTCCACAATTAAATAAAGAAGTCGGCAAAGACGAAGCCAAGGTCATTATC AAAACTAATCAGGGCGATATCACCCTCAAGCTCTTCCCCAAGTATGCACCGCTTGCTGTTGAAAACTTTTTAACACACGC CAAGGAAGGCTATTACGACAAGCTTTTGTTTCATCGGGTGATTAATAACTTTATGATTCAAACTGGTGATCCAAAGGGAG ACGGATCTGGCGGAGAATCCATTTGGAAGGGCAAGGACAGCAAAAAAGATGCGGGACAAGGCTTTGCTAATGAAATCTCA CCATTTTTATATAACATTCGAGGGGCTCTTGCTATGGCAAATGCCGGTGCAGATACTAATGGCAGCCAGTTCTTCATCAA TCAAAGCAAGCTCAACCAAGCCAAGGCCTTATCAGCCGATAATTACCCTAAGCCAATCATTGACGCCTACGAAGAAGGGG GCAATCCTAGCCTAGATGGCGGCTATACCGTTTTTGGTCAGGTTATTGAGGGTATGGATATCGTTGATAAAATAGCTGCC AGCCCAGTCGGCCCAAATGACAAGCCAATAGAGAACATCACTATTAATGCCATCGACATTGTTAAGGATTACTCCTTTAA AAAATAG
Upstream 100 bases:
>100_bases TTAGAAATAGTTAAAAAATAGACTTCGTCTCAATGCCCTTTAGCTTTATTTTCCAAGTCATTTTATGTTAAAATAAAAGA AATTGTTCTAAGGAGTACAC
Downstream 100 bases:
>100_bases CCTCTAAGCTACAACAACAATAAAACGACCAGCTCCTTATCGGAAAAGCCACCGATTCAAGAGCTGGTCGTGATTTTTTG CTATCAATTAAATAAAGAAG
Product: peptidyl-prolyl cis-trans isomerase cyclophilin-type
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 268; Mature: 268
Protein sequence:
>268_residues MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEAAAKAYEAKIKKALKADADQFPQLNKEVGKDEAKVII KTNQGDITLKLFPKYAPLAVENFLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSADNYPKPIIDAYEEGGNPSLDGGYTVFGQVIEGMDIVDKIAA SPVGPNDKPIENITINAIDIVKDYSFKK
Sequences:
>Translated_268_residues MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEAAAKAYEAKIKKALKADADQFPQLNKEVGKDEAKVII KTNQGDITLKLFPKYAPLAVENFLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSADNYPKPIIDAYEEGGNPSLDGGYTVFGQVIEGMDIVDKIAA SPVGPNDKPIENITINAIDIVKDYSFKK >Mature_268_residues MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEAAAKAYEAKIKKALKADADQFPQLNKEVGKDEAKVII KTNQGDITLKLFPKYAPLAVENFLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSADNYPKPIIDAYEEGGNPSLDGGYTVFGQVIEGMDIVDKIAA SPVGPNDKPIENITINAIDIVKDYSFKK
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI24308049, Length=184, Percent_Identity=42.3913043478261, Blast_Score=139, Evalue=4e-33, Organism=Homo sapiens, GI19557636, Length=187, Percent_Identity=39.0374331550802, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI7706339, Length=179, Percent_Identity=36.8715083798883, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI64276486, Length=111, Percent_Identity=48.6486486486487, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI20911035, Length=180, Percent_Identity=36.1111111111111, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI4758950, Length=175, Percent_Identity=36.5714285714286, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI22547212, Length=199, Percent_Identity=35.678391959799, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI7657473, Length=199, Percent_Identity=35.678391959799, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI22547215, Length=199, Percent_Identity=35.678391959799, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI4505991, Length=189, Percent_Identity=37.5661375661376, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI42560244, Length=183, Percent_Identity=34.4262295081967, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5454154, Length=181, Percent_Identity=34.8066298342541, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI4826932, Length=162, Percent_Identity=34.5679012345679, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI5031987, Length=158, Percent_Identity=36.7088607594937, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI10863927, Length=158, Percent_Identity=34.8101265822785, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI303305009, Length=162, Percent_Identity=32.7160493827161, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI5174637, Length=176, Percent_Identity=32.9545454545455, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI6631100, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI45439316, Length=158, Percent_Identity=32.9113924050633, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI14277126, Length=130, Percent_Identity=36.9230769230769, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI27735045, Length=183, Percent_Identity=30.6010928961749, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI150418007, Length=166, Percent_Identity=34.9397590361446, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI310129267, Length=158, Percent_Identity=33.5443037974684, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI310120620, Length=158, Percent_Identity=33.5443037974684, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI256017253, Length=176, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI221139811, Length=176, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI256017251, Length=176, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI310127646, Length=175, Percent_Identity=32.5714285714286, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI310114371, Length=175, Percent_Identity=32.5714285714286, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI310119221, Length=175, Percent_Identity=32.5714285714286, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI310110104, Length=172, Percent_Identity=33.1395348837209, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1786736, Length=188, Percent_Identity=37.2340425531915, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1789763, Length=178, Percent_Identity=35.9550561797753, Blast_Score=89, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17506311, Length=197, Percent_Identity=41.6243654822335, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17532641, Length=167, Percent_Identity=40.1197604790419, Blast_Score=116, Evalue=2e-26, Organism=Caenorhabditis elegans, GI71980594, Length=186, Percent_Identity=38.1720430107527, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17552780, Length=176, Percent_Identity=40.3409090909091, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI71980590, Length=174, Percent_Identity=37.9310344827586, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71997782, Length=154, Percent_Identity=38.961038961039, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17506307, Length=178, Percent_Identity=40.4494382022472, Blast_Score=106, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17539496, Length=179, Percent_Identity=36.3128491620112, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI32563659, Length=188, Percent_Identity=32.4468085106383, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17539498, Length=169, Percent_Identity=35.5029585798817, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17551282, Length=184, Percent_Identity=33.1521739130435, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17551284, Length=181, Percent_Identity=33.7016574585635, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17532643, Length=174, Percent_Identity=35.632183908046, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565860, Length=165, Percent_Identity=36.3636363636364, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17566266, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17552784, Length=191, Percent_Identity=30.8900523560209, Blast_Score=77, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6321848, Length=177, Percent_Identity=37.2881355932203, Blast_Score=95, Evalue=1e-20, Organism=Saccharomyces cerevisiae, GI6320510, Length=190, Percent_Identity=34.2105263157895, Blast_Score=83, Evalue=6e-17, Organism=Saccharomyces cerevisiae, GI6320359, Length=166, Percent_Identity=36.7469879518072, Blast_Score=82, Evalue=7e-17, Organism=Saccharomyces cerevisiae, GI6323562, Length=177, Percent_Identity=36.1581920903955, Blast_Score=79, Evalue=6e-16, Organism=Saccharomyces cerevisiae, GI6323246, Length=195, Percent_Identity=32.8205128205128, Blast_Score=77, Evalue=4e-15, Organism=Drosophila melanogaster, GI19922376, Length=192, Percent_Identity=37.5, Blast_Score=133, Evalue=2e-31, Organism=Drosophila melanogaster, GI17986117, Length=179, Percent_Identity=37.4301675977654, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI19922912, Length=185, Percent_Identity=41.6216216216216, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24652460, Length=187, Percent_Identity=34.7593582887701, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI21357249, Length=111, Percent_Identity=45.945945945946, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI20130249, Length=176, Percent_Identity=36.9318181818182, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21355677, Length=187, Percent_Identity=32.620320855615, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24586038, Length=184, Percent_Identity=34.7826086956522, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI45549139, Length=172, Percent_Identity=36.046511627907, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24664125, Length=160, Percent_Identity=37.5, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21357783, Length=160, Percent_Identity=37.5, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24650807, Length=183, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI17136360, Length=177, Percent_Identity=35.0282485875706, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI17647301, Length=158, Percent_Identity=35.4430379746835, Blast_Score=78, Evalue=8e-15,
Paralogues:
None
Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 29105; Mature: 29105
Theoretical pI: Translated: 5.24; Mature: 5.24
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEAAAKAYEAKIKKALKAD CHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC ADQFPQLNKEVGKDEAKVIIKTNQGDITLKLFPKYAPLAVENFLTHAKEGYYDKLLFHRV HHHCHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHH INNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEISPFLYNIRGALAMANAGADTN HHHHEEECCCCCCCCCCCCCHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC GSQFFINQSKLNQAKALSADNYPKPIIDAYEEGGNPSLDGGYTVFGQVIEGMDIVDKIAA CCEEEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC SPVGPNDKPIENITINAIDIVKDYSFKK CCCCCCCCCCCEEEEHHHHHHHCCCCCC >Mature Secondary Structure MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESEAAAKAYEAKIKKALKAD CHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC ADQFPQLNKEVGKDEAKVIIKTNQGDITLKLFPKYAPLAVENFLTHAKEGYYDKLLFHRV HHHCHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHH INNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEISPFLYNIRGALAMANAGADTN HHHHEEECCCCCCCCCCCCCHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC GSQFFINQSKLNQAKALSADNYPKPIIDAYEEGGNPSLDGGYTVFGQVIEGMDIVDKIAA CCEEEEEHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC SPVGPNDKPIENITINAIDIVKDYSFKK CCCCCCCCCCCEEEEHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA