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The map label for this gene is kdgR [H]

Identifier: 195978414

GI number: 195978414

Start: 1344058

End: 1345059

Strand: Direct

Name: kdgR [H]

Synonym: Sez_1309

Alternate gene names: 195978414

Gene position: 1344058-1345059 (Clockwise)

Preceding gene: 195978413

Following gene: 195978415

Centisome position: 66.4

GC content: 41.72

Gene sequence:

>1002_bases
ATGCAGCGCAAAGTAACCATCAATGATATTGCTGACTTAGCTAAAACTTCAAAAACAACTGTTTCTTTCTACCTCAACGG
TCGATTTGATAAAATGTCTCAGGAGACAAAAAGCCGGATCAAGGAGGCTATTGAAGCCACCAACTACAAGCCTAGCATTG
CAGCTCGCAGTCTCAATGCCAAGGCTACCAAATTGATTGGTGTGGTTATCGGTGACATCACCAATAGCTTTTCCAACCAG
ATTGTCAAAGGTATTGAAAGCAAGGCGCAAGAATTTGGTTATCAGATTATCATCGGCAACAGCAACTATGATCCTTCACG
TGAGGACGAATTGATTGAAAAAATGCTTAACCTAGGTGTAGATGGTTTTATCATTCAACCAACCTCTAACTTTAGAAAGT
ATTCACGCATCATCGAAGTGAAAAAAAAGCGCATGGTTTTCTTTGACAGTCAGCTCTATGAGCATCGTACAAACTGGGTC
AAGACCAACAATTATGACGCTGTTTATGACACCATTCAGCAATGCATCACCAAAGGCTATCAAAGCTTTATCATGGTTAC
TGGCAATCCTAATTTGCTGAGCACACGCATCGAGCGTGCTTCTGGTTTTATTGACGTTTTAGAGGCTAACCAGCTCCAGT
ATCGTCAAATGATCATCGATGAAAACCAAACCAGCTCTCAAGAAATTGCTCAGTTTCTACAAGGCGCATTTGATAAGGAA
CGTCACAATCTGGTATTTGTCCCAAACTGCTGGGCTCTGCCTAAGGTTTTTACTGCCATGAAGGCACTAAAGGTGTCATT
GCCAGAAACTGGTCTAGTTGGCTTTGATAACATCGAATGGACTCGCTTGTCATCACCAAGTATTACCACTATTATCCAGC
CTGCTTACGAAGAAGGGGAGCAAGCAACCAGCATTTTGATTGATGATATCGAAGGGCATAGCAAGGAAGCCAAGCAACAA
ATTTTTGATTGTCAGGTTAATTGGCAAGAATCGACCTTTTAA

Upstream 100 bases:

>100_bases
ACCTCTTCAAAGGTCATATTCTTGGACTGAAATATTAAAACAATTACCATTCCATATGTTATAATAAAACTACCAATGAT
GACAAAAAGGGGTCTATGCA

Downstream 100 bases:

>100_bases
CAGGATTTTTTTTATCTTCTAGACCTTAAAAAATCAGCCATTCTAATAACGATGACAAAACAACACGAGGCTTAACGCTT
GTTTGCTAGCATCAGAAAAA

Product: transcriptional regulator LacI family

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAIEATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQ
IVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMIIDENQTSSQEIAQFLQGAFDKE
RHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFDNIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQ
IFDCQVNWQESTF

Sequences:

>Translated_333_residues
MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAIEATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQ
IVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMIIDENQTSSQEIAQFLQGAFDKE
RHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFDNIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQ
IFDCQVNWQESTF
>Mature_333_residues
MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAIEATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQ
IVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMIIDENQTSSQEIAQFLQGAFDKE
RHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFDNIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQ
IFDCQVNWQESTF

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=25.3776435045317, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=27.6729559748428, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789068, Length=317, Percent_Identity=24.6056782334385, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787948, Length=310, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790715, Length=319, Percent_Identity=27.5862068965517, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=22.8125, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=22.8956228956229, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787906, Length=313, Percent_Identity=24.6006389776358, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=123, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788474, Length=322, Percent_Identity=21.4285714285714, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=25.0755287009063, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786540, Length=329, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37924; Mature: 37924

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAIEATNYKPSIAARSLNA
CCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
KATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCC
DGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWVKTNNYDAVYDTIQQCITKGY
CCEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCC
QSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMIIDENQTSSQEIAQFLQGAFDKE
CEEEEEECCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
RHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFDNIEWTRLSSPSITTIIQPAYEEGE
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHCCC
QATSILIDDIEGHSKEAKQQIFDCQVNWQESTF
HHHHHEEECCCCCHHHHHHHHHCCEECCCCCCC
>Mature Secondary Structure
MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAIEATNYKPSIAARSLNA
CCCEEEHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCC
KATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSNYDPSREDELIEKMLNLGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCC
DGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWVKTNNYDAVYDTIQQCITKGY
CCEEECCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCC
QSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMIIDENQTSSQEIAQFLQGAFDKE
CEEEEEECCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
RHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFDNIEWTRLSSPSITTIIQPAYEEGE
CCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEECCCHHCCC
QATSILIDDIEGHSKEAKQQIFDCQVNWQESTF
HHHHHEEECCCCCHHHHHHHHHCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]