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The map label for this gene is bceR [H]

Identifier: 195978127

GI number: 195978127

Start: 1041375

End: 1042040

Strand: Direct

Name: bceR [H]

Synonym: Sez_1004

Alternate gene names: 195978127

Gene position: 1041375-1042040 (Clockwise)

Preceding gene: 195978126

Following gene: 195978128

Centisome position: 51.45

GC content: 37.24

Gene sequence:

>666_bases
ATGATTAAAGCTGGAAAAATTTATATTGTCGAAGATGACGCTGCTGTCTTAACACCCTTAAAAGAGCACCTGAGTCAGAA
CTACCAGGTTCTTACCGTCTCTAACTTTAGAGACATAAAACAAGAAGTGATTGATTATAAACCGGATCTTATTCTTATGG
ACATCACCTTACCGTTTTTTAACGGCTTTTACTGGACCACAGAAATTCGTAAAACATCAACAATGCCAATTATTTTTATC
TCAAGCAGTAATGATGAGATGGATACGGTCATGGCACTTAATATGGGAGGAGATGATTTCATCTCCAAGCCCTTTTCTCT
AACCATTTTAGACGCAAAAATCGCAGCATTTTTAAGACGCTCACAGCAATTTAGCAGTGATGATGTGACCATAGATCAAT
TTAAGCTACATTTTGATGGTACCTTATCTAATGGCACAGATAGCATTCATTTATCGCCAACAGAGCACAAAATCTTAGCG
ATTTTATTTACTCACCCACAGCAAATTGTGTCAAAGGAAGATATTCTAGCAAGGCTTTGGGAAAACGAGAGCTTTATTGA
TCAAAACACGCTCAACGTTAACATGACGCGTTTACGCAAAAAAATATCAGCTATTGGTTTTGACCGTATTCACACAGTGA
GAGGAGTAGGCTATATTATCAAATGA

Upstream 100 bases:

>100_bases
TACTTTACCATTTACAGGATAACAAGCAGAACCTATTACAATATTATTGAACGATAAGACAAGTGGCGATTTTTCGCCAC
TTTTTTGATAAAATAATATT

Downstream 100 bases:

>100_bases
TAAGAGCATTTTTTAAGGAATATTATTCCTGGTATATCCAGTATGGGGTTGTTATGGCTGGTTATCTGCTGATCTTTTGG
CTTTATAGACTGCCTCTAAG

Product: TCS response regulator BceR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVIDYKPDLILMDITLPFFNGFYWTTEIRKTSTMPIIFI
SSSNDEMDTVMALNMGGDDFISKPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILA
ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGYIIK

Sequences:

>Translated_221_residues
MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVIDYKPDLILMDITLPFFNGFYWTTEIRKTSTMPIIFI
SSSNDEMDTVMALNMGGDDFISKPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILA
ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGYIIK
>Mature_221_residues
MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVIDYKPDLILMDITLPFFNGFYWTTEIRKTSTMPIIFI
SSSNDEMDTVMALNMGGDDFISKPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILA
ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGYIIK

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.2869955156951, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=28.3783783783784, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=28.8888888888889, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.2775330396476, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=30.4545454545455, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=25.6756756756757, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=28.6343612334802, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=25.6880733944954, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=28.8990825688073, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=24.6696035242291, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=28.8793103448276, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25250; Mature: 25250

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVIDYKPDLILMDITLPFF
CCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEEEHHH
NGFYWTTEIRKTSTMPIIFISSSNDEMDTVMALNMGGDDFISKPFSLTILDAKIAAFLRR
CCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCHHHHCCCEEEEEEHHHHHHHHHH
SQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILAILFTHPQQIVSKEDILARLW
HHCCCCCCEEEEEEEEEECCEECCCCCEEEECCCCCEEEEEEEECCHHHHCHHHHHHHHH
ENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGYIIK
CCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCEEEEC
>Mature Secondary Structure
MIKAGKIYIVEDDAAVLTPLKEHLSQNYQVLTVSNFRDIKQEVIDYKPDLILMDITLPFF
CCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCEEEEEEEEHHH
NGFYWTTEIRKTSTMPIIFISSSNDEMDTVMALNMGGDDFISKPFSLTILDAKIAAFLRR
CCEEEEEEEECCCCCEEEEEECCCCCCEEEEEEECCCHHHHCCCEEEEEEHHHHHHHHHH
SQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILAILFTHPQQIVSKEDILARLW
HHCCCCCCEEEEEEEEEECCEECCCCCEEEECCCCCEEEEEEEECCHHHHCHHHHHHHHH
ENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGYIIK
CCCCCCCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]