Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 195977985

GI number: 195977985

Start: 900557

End: 901087

Strand: Direct

Name: infC [H]

Synonym: Sez_0857

Alternate gene names: 195977985

Gene position: 900557-901087 (Clockwise)

Preceding gene: 195977984

Following gene: 195977986

Centisome position: 44.49

GC content: 39.17

Gene sequence:

>531_bases
GTGAAGATCATAGCTAAAAAAGATCTATTCATTAATGATGAGATTCGTGTTCGCGAAGTTCGTCTCGTTGGTCTTGAAGG
TGAACAATTAGGCATTAAACCATTATCTGAAGCTCAGTCTTTAGCTGATGCTGCAAATGTAGATTTGGTTTTAATCCAGC
CGCAAGCTGTTCCTCCTGTTGCCAAGCTTATGGACTATGGAAAGTTCAAATTTGAGTATCAAAAAAAGCAAAAGGAGCAA
CGCAAAAAGCAAAGCGTTGTAACTGTAAAGGAAGTACGTCTTAGCCCAGTTATCGACAAGGGTGACTTTGAAACAAAGCT
TCGTAATGGTCGTAAGTTCCTTGAAAAGGGAAATAAGGTTAAGGTTTCTATCCGTTTTAAAGGACGTATGATTACTCACA
AGGAGATTGGTGCTAAGGTACTGGCTGATTTTGCTGAGGCAACTCAAGATATTGCTATTATTGAGCAAAGAGCAAAAATG
GATGGTCGCCAAATGTTTATGCAGCTTGCACCAATTTCAGACAAGAAGTAA

Upstream 100 bases:

>100_bases
CTAGGTTGTCTGGCCCTACATGTCAAATTCCTATGGGATATTATGTGTGCGGGCTTGATTCATTAAGTCCGCTTTCGTTT
TTCTCTAAAAAAATAAAGAG

Downstream 100 bases:

>100_bases
TTGTCATATTACACTATATGTTAAGAGGAGAATATTAAAATGCCAAAACAAAAAACACACCGCGCATCAGCTAAACGTTT
TAAACGTACAGGTTCAGGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDKK

Sequences:

>Translated_176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDKK
>Mature_176_residues
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQ
RKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
DGRQMFMQLAPISDKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=162, Percent_Identity=52.4691358024691, Blast_Score=151, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20038; Mature: 20038

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPV
CCEEECCCCEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHH
AKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKV
HHHHHCCCCCHHHHHHHHHHHHHHHCEEHHHHEECCCCCCCCHHHHHHHHHHHHHCCCEE
KVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPV
CCEEECCCCEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHH
AKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKV
HHHHHCCCCCHHHHHHHHHHHHHHHCEEHHHHEECCCCCCCCHHHHHHHHHHHHHCCCEE
KVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
EEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA