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The map label for this gene is murA [H]

Identifier: 195977930

GI number: 195977930

Start: 833695

End: 834978

Strand: Direct

Name: murA [H]

Synonym: Sez_0801

Alternate gene names: 195977930

Gene position: 833695-834978 (Clockwise)

Preceding gene: 195977929

Following gene: 195977931

Centisome position: 41.19

GC content: 48.36

Gene sequence:

>1284_bases
ATGGAGAAGCTTGTGGATAAAATAATCATAGAAGGTGGGAGCACACGTTTAGAGGGAGAGGTAACGATCGAAGGCGCTAA
AAATGCCGTTCTTCCTTTACTAGCAGCTACTATCCTCCCCTCAACTGGAAAGACTGTCTTGAGAAATGTGCCGATTCTCT
CAGATGTTTTTACGATGAACCATGTTGTGCGTGGCCTAAATATTGACGTCGACTTTGATGAGGCTGCCAACCAGATTACA
GTTGATGCCTCAGGGGACATTTTAGATGTTGCCCCGTACGAGTATGTCAGCCAAATGCGCGCCTCAATTGTGGTTTTAGG
CCCGATTTTAGCTCGTAATGGCCATGCCAAGGTATCGATGCCTGGAGGCTGTACGATTGGCAGTAGGCCGATTGATTTGC
ATTTAAAGGGTCTAGAGGCTATGGGCGCTGAGATCACCCAGCAGGGTGGTGACATCACTGCAAAGGCAGATCGCCTAAAG
GGGGCGATGATCTATATGGACTTCCCATCAGTGGGGGCTACGCAAAATTTGATGATGGCAGCGACCCTTGCTGATGGTGT
GACAGTCATTGAAAATGCTGCCCGCGAGCCTGAGATTGTTGACCTAGCCCAGCTGCTCAACAAAATGGGGGCTAAGGTTC
GTGGGGCAGGTACCGAAACCCTGACCATAACGGGTGTCACCAGTCTATGTGGTGTTGAGCATGATGTTGTTCAGGATCGT
ATCGAAGCAGGTACCTTTATGATTGCTGCAGCAATGACCTCTGGTAATGTGCTGATTAGAGATGCTGTATGGGAGCATAA
TCGGCCCTTGATTTCTAAGCTCATGGAAATGGGAGTGTCTGTTGTCGAAGAGGACGCAGGCATTAGGGTGCAGGCTGATG
TGACTAAGCTAAAGCCTGTCACTGTTAAAACCCTTCCTCACCCAGGCTTTCCAACAGATATGCAGGCTCAGTTTACAGCC
CTTATGGCCATTGTTAAGGGAGAATCTACAATGGTGGAAACAGTCTTTGAAAATCGTTTCCAGCACTTAGAAGAAATGCG
ACGCATGGGCTTACAATCTGAGGTATTGCGTGATACAGCCATGATTCATGGTGGTCATGAATTGCAGGGGGCGCCTGTGA
TGTCAACAGACCTGCGAGCTAGTGCAGCCCTCATCTTAACGGGAATGGTTGCCAAGGGCAGGACCACTGTTAATAAGTTG
AACCATTTAGATCGTGGCTATTATCAGTTTCATGAAAAGCTTGCCAAGCTAGGTGCCAACATTCAGCGAATTAGTGAGGA
GTAG

Upstream 100 bases:

>100_bases
GCTGGAATTAATTCAGATTAGTCAGTATCTGCTGTATGATTTCCACTAGAGTAGGCAGTCAGGAAGTATGATATAATATT
AGTACAATGACCAGTAGGAA

Downstream 100 bases:

>100_bases
TCAATGACTAATGGTTGGAGATATGTCATAAATCAGCTAATGCTAATCATAGCTATTGGACTGCTAGGACTCTTTTGTCT
GGCGCTGGGACTAGTGATTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MEKLVDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLRNVPILSDVFTMNHVVRGLNIDVDFDEAANQIT
VDASGDILDVAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLK
GAMIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLTITGVTSLCGVEHDVVQDR
IEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVVEEDAGIRVQADVTKLKPVTVKTLPHPGFPTDMQAQFTA
LMAIVKGESTMVETVFENRFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTTVNKL
NHLDRGYYQFHEKLAKLGANIQRISEE

Sequences:

>Translated_427_residues
MEKLVDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLRNVPILSDVFTMNHVVRGLNIDVDFDEAANQIT
VDASGDILDVAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLK
GAMIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLTITGVTSLCGVEHDVVQDR
IEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVVEEDAGIRVQADVTKLKPVTVKTLPHPGFPTDMQAQFTA
LMAIVKGESTMVETVFENRFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTTVNKL
NHLDRGYYQFHEKLAKLGANIQRISEE
>Mature_427_residues
MEKLVDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLRNVPILSDVFTMNHVVRGLNIDVDFDEAANQIT
VDASGDILDVAPYEYVSQMRASIVVLGPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLK
GAMIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLTITGVTSLCGVEHDVVQDR
IEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVVEEDAGIRVQADVTKLKPVTVKTLPHPGFPTDMQAQFTA
LMAIVKGESTMVETVFENRFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTTVNKL
NHLDRGYYQFHEKLAKLGANIQRISEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=47.877358490566, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45944; Mature: 45944

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLVDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLRNVPILSDVFTMN
CHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
HVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVLGPILARNGHAKVSM
HHHHCCCEEEEHHCCCCEEEEECCCCEEECCCHHHHHHHHHCEEEEEHHHCCCCCEEEEC
PGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLKGAMIYMDFPSVGATQNLMMA
CCCCCCCCCCEEEEECCHHHHCHHHHHCCCCEEEEHHHCCCEEEEEECCCCCCCCHHHEE
ATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLTITGVTSLCGVEHDVVQDR
HHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECHHHHHCCHHHHHHHH
IEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVVEEDAGIRVQADVTKLKPV
HHCCEEEEEEEECCCCEEEEECHHCCCCHHHHHHHHCCHHHEECCCCEEEEECHHHCCCE
TVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFENRFQHLEEMRRMGLQSEVLRDTA
EEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTTVNKLNHLDRGYYQFHEKLAKLGAN
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
IQRISEE
HHHHCCC
>Mature Secondary Structure
MEKLVDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLRNVPILSDVFTMN
CHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHH
HVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVLGPILARNGHAKVSM
HHHHCCCEEEEHHCCCCEEEEECCCCEEECCCHHHHHHHHHCEEEEEHHHCCCCCEEEEC
PGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKADRLKGAMIYMDFPSVGATQNLMMA
CCCCCCCCCCEEEEECCHHHHCHHHHHCCCCEEEEHHHCCCEEEEEECCCCCCCCHHHEE
ATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLTITGVTSLCGVEHDVVQDR
HHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCEEECCCCCEEEEECHHHHHCCHHHHHHHH
IEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVSVVEEDAGIRVQADVTKLKPV
HHCCEEEEEEEECCCCEEEEECHHCCCCHHHHHHHHCCHHHEECCCCEEEEECHHHCCCE
TVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFENRFQHLEEMRRMGLQSEVLRDTA
EEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTTVNKLNHLDRGYYQFHEKLAKLGAN
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
IQRISEE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]